You are here: Home> South Korea>K-REACH>CAS 109-99-9> CAS 109-99-9 | Data Package > 1000 t/a + CSR
| Study name | Short Description | Data Owner |
|---|---|---|
| CSR | Chemical Safety Report | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Description of appearance/physical state/colour of tetrahydrofuran | Author: LyondellBasell Industries | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Description of appearance/physical state/colour of tetrahydrofuran | Author: LyondellBasell Industries | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 2009 on CD-ROM | Author: Lide D.R. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: The Merck Index eleventh edition | Author: Budavari S. O'Neil M.J. Smith A. Heckelman P.E. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics on CD-ROM | Author: Lide D.R. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Hawleys condensed chemical dictionary 15th edition | Author: Lewis R.J. | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: The Merck Index eleventh edition | Author: Budavari S. O'Neil M.J. Smith A. Heckelman P.E. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Kirk-Othmer concise encyclopedia of chemical technolgy. 4th Edition. | Author: Kroschwitz J. Kirk R.E. Othmer D.F. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of environmetal fate and exposure data for organic chemicals: Solvent v2. | Author: Howard P.H. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Bestimmung des Verteilungskoeffizienten log Pow von Tetrahydrofuran in 1-Octanol/Wasser bei 25 C | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Bestimmung des Verteilungskoeffizienten log Pow von Tetrahydrofuran in 1-Octanol/Wasser bei 25 C | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics on CD-ROM | Author: Lide D.R. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Kirk-Othmer encylcopedia of chemical technology. 5 edition. 2004. | Author: Kirk R.E. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Handbook of environmental fate and exposure data for organic chemicals: solvents v2 | Author: Howard P.H. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Dangerous properties of Industrial Materials 8th Edition. | Author: Sax N.I. Lewis R.J. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Simple method to prolong the closed bottle test for the determination of the inherent biodegradability | Author: Van Ginkel C.G. Stroo C.A. | Year: 1992 | Guideline: 301 D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Final report - Respirometric test | Author: BASF AG | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Final report - Respirometric test | Author: BASF AG | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Final Report - Determination of the Biodegradability of Tetrahydrofuran in the Manometric Respirometry Test (EU Document 89/436/XI OECD 301F/1991-draft ISO 9408:1981) | Author: BASF AG | Year: 1992 | Guideline: 301 F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Final Report - Determination of the Biodegradability of Tetrahydrofuran in the Manometric Respirometry Test (EU Document 89/436/XI, OECD 301F/1991-draft, ISO 9408:1981) | Author: BASF AG | Year: 1992 | Guideline: 301 F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Soil sorption of volatile and semivolatile organic compounds in a mixture. | Author: Walton B.T. et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicities of organic chemicals to Fathead Minnows (Pimephales promelas) | Author: Brooke L.T. Call D.J. Geiger D.L. Northcott C.E. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: 96-hour LC50 to Fathead Minnow | Author: Haskell Laboratory | Year: 1982 | Guideline: 203 | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: 96-hour LC50 to Fathead Minnow | Author: Haskell Laboratory | Year: 1982 | Guideline: 203 | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: 48-hour LC50 to Daphnia magna | Author: Haskell Laboratory | Year: 1980 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: 48-hour LC50 to Daphnia magna | Author: Haskell Laboratory | Year: 1980 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Results of toxic action of water pollutants on Daphnia magna Straus tested by an improved standardized procedure. | Author: Bringmann V.G. Kuhn R. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefahrdender stoffe gegen bakterien (Pseudomonas putida) und Grunalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann V.G. Kuhn R. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute toxicity and limits of solvent residue for sixteen organic solvents | Author: Kimura E.T. Ebert D.M. and Dodge P.W. | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute Inhalation Toxicity in Rats | Author: E.I. du Pont de Nemours and Company | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Acute Inhalation Toxicity in Rats | Author: E.I. du Pont de Nemours and Company | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Tetrahydrofuran: Acute Dermal Toxicity in Rats | Author: BASF | Year: 2009 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Tetrahydrofuran: Acute Dermal Toxicity in Rats | Author: BASF | Year: 2009 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Tetrahydrofuran: Acute dermal toxicity study in rats | Author: BASF study director | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Tetrahydrofuran: Acute dermal toxicity study in rats | Author: BASF study director | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Federal Hazardous Substances Act Test - Rabbit Eye Irritation | Author: E.I. du Pont de Nemours and Company | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Federal Hazardous Substances Act Test - Rabbit Eye Irritation | Author: E.I. du Pont de Nemours and Company | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: H-7170: Federal Hazardous Substances Act Test - Rabbit Eye Irritation | Author: DuPont Study Director | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Review of Available Data | Author: Harlan Laboratories Ltd. | Year: 2008 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Review of Available Data | Author: Harlan Laboratories Ltd. | Year: 2008 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Results of a Short-Term Toxicity Study for Three Organic Chemicals Found in Niagara River Drinking Water | Author: Komsta E. Chu I. Secours V.E. Valli V.E. and Villeneuve D.C. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Tetrahydrofuran: in vitro gene mutation test in CHO cells (HPRT locus assay) | Author: BASF SE | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Tetrahydrofuran: in vitro gene mutation test in CHO cells (HPRT locus assay) | Author: BASF SE | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: II Results from the testing of 270 chemicals | Author: Mortelmans K. Haworth S. Lawlor T. Speck W. Tainer B. and Zeiger E. | Year: 1986 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberrations and sister chromatid exchange tests in vitro in Chinese hamster ovary cells: Evaluations of 108 chemicals | Author: Galloway S.M. et al. | Year: 1987 | Guideline: 479 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Ames test for Tetrahydrofuran | Author: BASF AG | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Ames test for Tetrahydrofuran | Author: BASF AG | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Ames test for Tetrahydrofuran stabilized by BHT | Author: BASF AG | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Ames test for Tetrahydrofuran stabilized by BHT | Author: BASF AG | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: f | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Tetrahydrofuran - Two-Generation Reproduction Toxicity Study in Wistar Rats Continuous Administration in the Drinking Water | Author: BASF | Year: 1996 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Tetrahydrofuran - Two-Generation Reproduction Toxicity Study in Wistar Rats Continuous Administration in the Drinking Water | Author: BASF | Year: 1996 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: One-generation reproduction Toxicity Study of Tetrahydrofuran in rats. Administration in the drinking water | Author: BASF AG | Year: 1994 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: One-generation reproduction Toxicity Study of Tetrahydrofuran in rats. Administration in the drinking water | Author: BASF AG | Year: 1994 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Evaluation of the Potential for Developmental Toxicity in Rats and Mice following Inhalation Exposure to Tetrahydrofurn | Author: Mast T.J. Weigel R.J. Westerberg R.B. Schwetz B.A. and Morrissey R.E. | Year: 1992 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Evaluation of the Potential for Developmental Toxicity in Rats and Mice following Inhalation Exposure to Tetrahydrofurn | Author: Mast T.J. Weigel R.J. Westerberg R.B. Schwetz B.A. and Morrissey R.E. | Year: 1992 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics on CD-ROM | Author: Lide D.R. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Tetrahydrofuran Teratogenicity - Results of Pilot Study (Part I) | Author: E.I. du Pont de Nemours & Company | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Tetrahydrofuran Teratogenicity - Results of Pilot Study (Part I) | Author: E.I. du Pont de Nemours & Company | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Kirk-Othmer concise encyclopedia of chemical technology. 4th Edition. | Author: Kroschwitz J.I. Kirk R.E. Othmer D.F. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law | Author: National Institute of Technology and Evaluation | Year: 2002 | Guideline: 302 C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Fish subchronic toxicity prediction model for industrial organic chemicals that produce narcosis. | Author: Call D.J. Brooke L.T. Knuth M.L. Poirer S.H. Hoglund M.D. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Oxygen uptake rate inhibition test: A modified method for priority pollutants | Author: Talinli I. Tokta S. | Year: 1994 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Unpublished report | Author: BASF AG | Year: 1992 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Unpublished report | Author: BASF AG | Year: 1992 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Unpublished report | Author: BASF AG | Year: 1991 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Unpublished report | Author: BASF AG | Year: 1991 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Chemical Mutagenesis Testing in Drosophila. III. Results of 48 Coded Compounds Tested for the National Toxicology Program | Author: Valencia R. Mason J.M. Woodruff R.C. and Zimmering S. | Year: 1985 | Guideline: 477 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Tetrahydrofuran (CAS No. 109-99-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) | Author: NTP | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |