You are here: Home> South Korea>K-REACH>CAS 110-17-8> CAS 110-17-8 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: A ready-reference book of chemical and physical data | Author: Weast RC (Ed) | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: An encyclopedia of chemicals and drugs | Author: Stecher PG et al. | Year: 1968 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: An encyclopedia of chemicals and drugs | Author: Stecher PG et al. | Year: 1968 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Year: 1974-1975 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Particle Size Distribution I CIPAC MT 187 | Author: Smeykal H. | Year: 2010 | Guideline: 110 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Particle Size Distribution I CIPAC MT 187 | Author: Smeykal H. | Year: 2010 | Guideline: 110 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Chemical Data Records | Author: Howard PH, Meylan WM (Eds) | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Chemical Data Records | Author: Howard PH, Meylan WM (Eds) | Year: 1997 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Partition Coefficient n-octanol/water | Author: Kainzbauer J. | Year: 2013 | Guideline: 107 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Partition Coefficient n-octanol/water | Author: Kainzbauer J. | Year: 2013 | Guideline: 107 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Chemical Data Records | Author: Howard PH, Meylan WM (Eds) | Year: 1997 | Guideline: A.6 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Hommel - Handbuch der gefährlichen Güter | Author: Anonymous | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Flammability | Author: Wenighofer T. | Year: 2010 | Guideline: A.10 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Flammability | Author: Wenighofer T. | Year: 2010 | Guideline: A.10 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: An encyclopedia of chemicals and drugs | Author: Stecher PG et al. | Year: 1968 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Fumaric acid: Carbon dioxide evolution test for ready biodegradability | Author: Ipser A | Year: 2010 | Guideline: 301B | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: FUMARIC ACID: Carbon Dioxide Evolution Test for Ready Biodegradability | Author: Ipser A. | Year: 2010 | Guideline: 301B | Klimisch score: 1 - Reliable without restriction. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fumaric acid: acute toxicity to fish | Author: Ipser A | Year: 2010 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fumaric acid: acute toxicity to fish | Author: Ipser A. | Year: 2010 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Detoxification of specific organic substances by wet oxidation | Author: Randall TL, Knopp PV | Year: 1980 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Fumaric acid: Acute toxicity study for Daphnia magna | Author: Ipser A | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Fumaric acid: Acute toxicity study for Daphnia magna | Author: Ipser A. | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Fumaric acid: algae (Pseudokirchneriella subcapitata) growth inhibition test | Author: Ipser A. | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Fumaric acid: algae (Pseudokirchneriella subcapitata) growth inhibition test | Author: Ipser A. | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction. | - |
| Eco-Tox | Toxicity to aquatic plants other than algae | Robust Study Summary -- Title: Inhibition of Salvinia (Salvinia molesta Mitchell) by Parthenium (Parthenium hysterophorus L.) I. Effect of Leaf Residue and Allelochemicals | Author: Pandey DK. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Fumaric acid: Activated sludge respiration inhibition test | Author: Ipser A. | Year: 2010 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Fumaric acid: Activated sludge respiration inhibition test | Author: Ipser A. | Year: 2010 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The fumarate content of certain tissues of the rat as determined by partition chromatography. | Author: Marshall et al. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Report of the Scientific Committee on Animal Nutrition on the safety of fumaric acid | Author: Scientific Committee for Animal Nutrition (SCAN) of the European Commission | Year: 2003 | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on Food Additives | Author: Joint FAO/WHO Expert Committee on Food Additives | Year: 1999 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions | Author: Vernot et al. | Year: 1977 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Fumaric acid: Acute Inhalation Toxicity in Rats | Author: Wuschko S. | Year: 2010 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: FUMARIC ACID: Acute Inhalation Toxicity in Rats | Author: Wuschko, S. | Year: 2010 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions | Author: Vernot et al. | Year: 1977 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT) | Author: Kreiling R et al. | Year: 2008 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Comparison of the skin sensitizing potential of unsaturated compounds as assessed by the murine local lymph node assay (LLNA) and the guinea pig maximization test (GPMT) | Author: Kreiling R. | Year: 2008 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals | Author: Zeiger E et al. | Year: 1988 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Primary mutagenicity screening of food additives currently used in Japan | Author: Ishidate M. et al. | Year: 1984 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays | Author: Seifried HE et al. | Year: 2006 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: A compilation of two decades of mutagenicity test results with the Ames Salmonella typhimurium and L5178Y mouse lymphoma cell mutation assays | Author: Seifried et al. | Year: 2006 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Primary mutagenicity screening of food additives currently used in Japan | Author: Ishidate et al. | Year: 1984 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Cell mutation assay at the thymidine kinase locus (TK+/-) in mouse lymphoma L5178Y cells with fumaric acid | Author: Wollny, H-E. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Cell mutation assay at the thymidine kinase locus (TK+/-) in mouse lymphoma L5178Y cells with fumaric acid | Author: Wollny, H-E. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Final report on the safety assessment of malic acid and sodium malate | Author: Fiume MZ | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. Read-Across (CAS 6915-15-7 | EC 230-022-8 | malic acid). |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: A study to determine the toxicity of fumaric acid | Author: Levey S et al. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |