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CAS 22984-54-9 | Data Package 10 - 100 t/a

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Study name Short Description Data Owner
Repeated dose toxicity: oral Robust Study Summary -- Title: 2-Butanone, O,O',O''-(methylsilylidyne) trioxime. Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in the Rat; | Author: RCC | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Repeated dose toxicity: oral Right to refer to study -- Title: 2-Butanone, O,O',O''-(methylsilylidyne) trioxime. Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in the Rat; | Author: RCC | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: 2-Butanone, O,O',O''-(methylsilylidyne) trioxime. Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in the Rat; | Author: RCC | Year: 2008 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Right to refer to study -- Title: 2-Butanone, O,O',O''-(methylsilylidyne) trioxime. Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in the Rat; | Author: RCC | Year: 2008 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: Butan-2-one-O, O',O"-(methylsilyldyne)trioxime (CAS No: 22984-54-9): Determination of vapour pressure; | Author: Tremain S P | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Vapour pressure Right to refer to study -- Title: Butan-2-one-O, O',O"-(methylsilyldyne)trioxime (CAS No: 22984-54-9): Determination of vapour pressure; | Author: Tremain S P | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: In vitro Mammalian Cell Gene Mutation Assay (Thymidine Kinase Locus/TK+/-) in Mouse Lymphoma L5178Y Cells with Butan-2-one O,O',O''-(methylsilylidyne)trioxime; | Author: BSL BIOSERVICE | Year: 2011 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Right to refer to study -- Title: In vitro Mammalian Cell Gene Mutation Assay (Thymidine Kinase Locus/TK+/-) in Mouse Lymphoma L5178Y Cells with Butan-2-one O,O',O''-(methylsilylidyne)trioxime; | Author: BSL BIOSERVICE | Year: 2011 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: In Vitro Mammalian Chromosome Aberration Test with Methyltris (methylethylketoxime)silane (CAS number 22984-54-9); | Author: BioReliance | Year: 2004 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: In Vitro Mammalian Chromosome Aberration Test with Methyltris (methylethylketoxime)silane (CAS number 22984-54-9); | Author: BioReliance | Year: 2004 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Appearance/physical state/colour Robust Study Summary -- Title: Determination of the freezing point/freezing range and of the boiling point/boiling range with 2-butanone, O, O',O"-(methylsilylidyne)trioxime (CAS No: 22984-54-9); ; | Author: Franke J | Year: 2009 | Guideline: 0 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Appearance/physical state/colour Right to refer to study -- Title: Determination of the freezing point/freezing range and of the boiling point/boiling range with 2-butanone, O, O',O"-(methylsilylidyne)trioxime (CAS No: 22984-54-9); ; | Author: Franke J | Year: 2009 | Guideline: 0 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Test pour l'évaluation de la toxicité aiguë par administration cutan´e unique (LD50), chez le rat.; | Author: Hazleton-IFT | Year: 1987 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: dermal Right to refer to study -- Title: Test pour l'évaluation de la toxicité aiguë par administration cutanée unique (LD50), chez le rat.; | Author: Hazleton-IFT | Year: 1987 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Robust Study Summary -- Title: Test pour l'évaluation de la toxicité aiguë par administration orale unique (DL 50), chez le rat (Test to evaluate acute toxicity using a single oral administration (LD 50), in the rat). ; | Author: Hazleton-IFT | Year: 1987 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Right to refer to study -- Title: Test pour l'évaluation de la toxicité aiguë par administration orale unique (DL 50), chez le rat (Test to evaluate acute toxicity using a single oral administration (LD 50), in the rat). ; | Author: Hazleton-IFT | Year: 1987 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Explosive properties Robust Study Summary -- Title: DETERMINATION OF THE EXPLOSIVE PROPERTIES OF BUTAN-2-ONE O,O',O''-(METHYLSILYLIDYNE)TRIOXIME ; | Author: Baltussen, E. | Year: 2012 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Explosive properties Right to refer to study -- Title: DETERMINATION OF THE EXPLOSIVE PROPERTIES OF BUTAN-2-ONE O,O',O''-(METHYLSILYLIDYNE)TRIOXIME ; | Author: Baltussen, E. | Year: 2012 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Methyltris(methylethylketoxime)silane: Toxicity to the Green Alga (Selenastrum capricornutum) Under Static Test Conditions.; | Year: 2007 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Methyltris(methylethylketoxime)silane: Toxicity to the Green Alga (Selenastrum capricornutum) Under Static Test Conditions.; | Year: 2007 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin sensitisation Robust Study Summary -- Title: Guinea pig maximization test of Tetraoximino Silane (TOS).; | Author: Allied Corporation | Year: 1985 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Methyltris(methylethylketoxime)silane: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions. ; | Year: 2007 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to fish Right to refer to study -- Title: Methyltris(methylethylketoxime)silane: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions. ; | Year: 2007 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Methyltris (methylethylketoxime)silane: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions. ; | Year: 2007 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Methyltris (methylethylketoxime)silane: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions. ; | Year: 2007 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Hydrolysis Robust Study Summary -- Title: Hydrolysis of methyltris(methylethylketoxime)-silane (CAS 22984-54-9); | Author: Miller J A | Year: 2004 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Hydrolysis Right to refer to study -- Title: Hydrolysis of methyltris(methylethylketoxime)-silane (CAS 22984-54-9); | Author: Miller J A | Year: 2004 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Robust Study Summary -- Title: Flash Point, Autoignition temperature, and lower and upper flammability limits of selected silicon intermediates - III; | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Right to refer to study -- Title: Flash Point, Autoignition temperature, and lower and upper flammability limits of selected silicon intermediates - III; | Author: Dow Corning Corporation | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: Test pour l'éevaluation de l'irritation et de la corrosion oculaires aiguës, chez le lapin. ; | Author: Hazleton-IFT | Year: 1987 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: Test pour l'evaluation de l'irritation et de la corrosion oculaires aiguës, chez le lapin. ; | Author: Hazleton-IFT | Year: 1987 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Guideline: 301 A-F | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Dichloro(methyl)(vinyl)silane: Determining the Ready Biodegradability; | Author: Baumgartner D | Year: 2009 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Dichloro(methyl)(vinyl)silane: Determining the Ready Biodegradability; | Author: Baumgartner D | Year: 2009 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Density Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions; | Author: Peter Fisk Associates | Year: 2011; 2011 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions; | Author: Peter Fisk Associates | Year: 2011; 2011 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Oxidising properties Waiver -
Boiling point Robust Study Summary -- Title: Determination of the freezing point/freezing range and of the boiling point/boiling range with 2-butanone, O, O',O"-(methylsilylidyne)trioxime (CAS No: 22984-54-9); | Author: Franke J | Year: 2009 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -
Boiling point Right to refer to study -- Title: Determination of the freezing point/freezing range and of the boiling point/boiling range with 2-butanone, O, O',O"-(methylsilylidyne)trioxime (CAS No: 22984-54-9); | Author: Franke J | Year: 2009 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -
Skin irritation / corrosion Robust Study Summary -- Title: Silane 196-methyltis(methylethylcetiminoxy)Silane. Test pour l'evaluation de l'irritation primaire det de la corrosion cutanees aiguës, chez le lapin.; | Author: Hazleton-IFT | Year: 1987 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Skin irritation / corrosion Right to refer to study -- Title: Silane 196-methyltis(methylethylcetiminoxy)Silane. Test pour l'evaluation de l'irritation primaire det de la corrosion cutanees aiguës, chez le lapin.; | Author: Hazleton-IFT | Year: 1987 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Water solubility Robust Study Summary -- Title: Screening Assessment for the Challenge 2-Butanone, oxime (Butanone oxime) Chemical Abstracts Service Registry Number 96-29-7; Handbook of environmental data on organic chemicals; | Author: Environment Canada; Verschueren K | Year: 2010; 1977 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Partition coefficient Robust Study Summary -- Title: Screening Assessment for the Challenge 2-Butanone, oxime (Butanone oxime) Chemical Abstracts Service Registry Number 96-29-7; | Year: 2010 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -