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CAS 637-92-3 | Data Package 100 - 1000 t/a

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Includes:

Study name Short Description Data Owner
Appearance/physical state/colour Robust Study Summary -- Title: n-Octanol/water partition coefficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 C +/- 1C. | Author: Montgomery CR | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Appearance/physical state/colour Right to refer to study -- Title: n-Octanol/water partition coefficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 C +/- 1C. | Author: Montgomery CR | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: No information | Author: SRC EPIWIN | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: No information | Author: SRC EPIWIN | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Robust Study Summary -- Title: ETBE as a gasoline blending component: the experience of Elf Aquataine. | Author: Chatin L Fombarlet C Bernasconi C Gauthier A and Schmelzle P. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Robust Study Summary -- Title: Volatility characteristics of blends of gasoline with ethyl tertiary butyl ether (ETBE). | Author: Furey RL and Perry KL | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Density Robust Study Summary -- Title: ETBE as a gasoline blending component: the experience of Elf Aquataine. | Author: Chatin L Fombarlet C Bernasconi C Gauthier A and Schmelzle P. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Robust Study Summary -- Title: Volatility characteristics of blends of gasoline with ethyl tertiary butyl ether (ETBE). | Author: Furey RL and Perry KL | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Vapour pressure Robust Study Summary -- Title: ETBE: determination of the vapour pressure. | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Vapour pressure Right to refer to study -- Title: ETBE: determination of the vapour pressure. | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: ETBE as a gasoline blending component: the experience of Elf Aquataine. | Author: Chatin L Fombarlet C Bernasconi C Gauthier A and Schmelzle P. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Vapour pressure Robust Study Summary -- Title: Volatility characteristics of blends of gasoline with ethyl tertiary butyl ether (ETBE). | Author: Furey RL and Perry KL | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Partition coefficient Robust Study Summary -- Title: n-Octanol/water partition coefficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 C +/- 1C. | Author: Biodevelopment Laboratories Inc. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Partition coefficient Right to refer to study -- Title: n-Octanol/water partition coefficient (Kow) for ethyl tertiary butyl ether (ETBE) at 25 C +/- 1C. | Author: Biodevelopment Laboratories Inc. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Partition coefficient Robust Study Summary -- Title: Relationship between lipophilic character and anesthetic activity. | Author: Glave WR and Hansch C | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Robust Study Summary -- Title: Study of fuel oxygenates solubility in aqueous media as a function of temperature and tert-butyl alcohol concentration | Author: Gonzales-Olmos R. Iglesias M. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Water solubility Robust Study Summary -- Title: ETBE as a gasoline blending component: the experience of Elf Aquitaine. | Author: Chatin L Fombarlet C Bernasconi C Gauthier A and Schmelzle P. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Right to refer to study -- Title: ETBE as a gasoline blending component: the experience of Elf Aquitaine. | Author: Chatin L Fombarlet C Bernasconi C Gauthier A and Schmelzle P. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Appearance/physical state/colour Robust Study Summary -- Title: ETBE: Determination of physico-chemical properties | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Appearance/physical state/colour Right to refer to study -- Title: ETBE: Determination of physico-chemical properties | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Flash point Robust Study Summary -- Title: 8.1-EXL-4900.2006 "Empfohlene Sicherheitstechnische Kenngroessen" | Author: PTB-Laboratorium 3.43 | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Auto-ignition temperature Robust Study Summary -- Title: ETBE: Determination of physico-chemical properties. | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Auto-ignition temperature Right to refer to study -- Title: ETBE: Determination of physico-chemical properties. | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Viscosity Robust Study Summary -- Title: ETBE: Determination of physico-chemical properties. | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Viscosity Right to refer to study -- Title: ETBE: Determination of physico-chemical properties. | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Viscosity Robust Study Summary -- Title: Volatility characteristics of blends of gasoline with ethyl tertiary butyl ether (ETBE). | Author: Furey RL and Perry KL | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Ready Biodegradability 'Determination of BOD - Closed Bottle Test' Test substance: TAME (tert-amyl methyl ether) In comparison with: MTBE (Methyl tert-butyl ether) a ETBE (Ethyl tert-butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Guideline: 301 D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Ready Biodegradability 'Determination of BOD - Closed Bottle Test' Test substance: TAME (tert-amyl methyl ether) In comparison with: MTBE (Methyl tert-butyl ether) a ETBE (Ethyl tert-butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Guideline: 301 D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Aerobic degradation of ethyl-tert-butyl ether by a microbial consortium: selection and evaluation of biodegradation ability | Author: Kharoune M Kharoune L Lebault J-M and Pauss A | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation of the gasoline oxygenates MTBE ETBE TAME TBA and TAA by aerobic mixed cultures | Author: Cowan RM and Park K | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Isolation of two aerobic bacterial strains that degrade efficiently ethyl tert-butyl ether (ETBE) | Author: Fayolle F Hernandez G Le Roux F and Vandecasteele J-P | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Isolation and characterisation of a bacterial consortium that mineralises ethyl tert-butyl ether | Author: Kharoune M Kharoune T Ribero T Pauss A and Lebeault JM | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Ethyl tert-butyl ether biodegradation in aerobic upflow fixed-bed biofilm reactor | Author: Kharoune M Pauss A and Lebeault JM | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Isolation and characterization of two aerobic bacterial strains that completely degrade ethyl tert-butyl ether (ETBE) | Author: Kharoune M Kharoune L Lebeault JM and Pauss A | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation of the gasoline oxygenates methyl tert-butyl ether ethyl-tert butyl ether and tert-amyl methyl ether by propane oxidizing bacteria | Author: Steffan RJ McClay K Vainberg S Condee CW and Zhang D | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Anaerobic degradation of gasoline oxygenates: extrapolation of information to multiple sites and redox conditions | Author: Mormile M Liu S and Sulfita JM | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Anaerobic biodegradation of known and potential gasoline oxygenates in the terrestrial subsurface | Author: Sulfita JM and Mormille MR | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Short-term toxicity to fish Robust Study Summary -- Title: Acute lethal toxicity with Poecilia reticulata | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to fish Right to refer to study -- Title: Acute lethal toxicity with Poecilia reticulata | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Acute Toxicity of Methyl-Tertiary Butyl Ether (MTBE) to Aquatic Organisms | Author: BenKinney MT Barbieri JF Gross JS & Naro PA | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Cranofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME. | Author: Bonventre JA White LA Cooper KR | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Long-term toxicity to fish Robust Study Summary -- Title: Cranofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME. | Author: Boventre JA White LA Cooper KR | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Ethyl tert-butyl ether (ETBE): acute toxicity to Daphnia magna | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Ethyl tert-butyl ether (ETBE): acute toxicity to Daphnia magna | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute toxicity of ethyl tertiary butyl ether to the mysid Mysidopsis bahia | Author: T.R. Wilbury Laboratories Inc. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Acute toxicity of ethyl tertiary butyl ether to the mysid Mysidopsis bahia | Author: T.R. Wilbury Laboratories Inc. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute immobilization test with Daphnia magna | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Acute immobilization test with Daphnia magna | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Methyl tertiary-butyl ether a flow-through life-cycle toxicity test with the cladoceran (Daphnia magna) | Author: Wildlife International Ltd. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: TAME: Flow-through chronic toxicity to the mysid Americamysis bahia | Author: T.R. Wilbury Laboratories Inc. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: TAME: Flow-through chronic toxicity to the mysid Americamysis bahia | Author: T.R. Wilbury Laboratories Inc. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Ethyl tert-butyl ether (ETBE): algal inhibition test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Ethyl tert-butyl ether (ETBE): algal inhibition test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Alga growth inhibition test | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Alga growth inhibition test | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicity to microorganisms Robust Study Summary -- Title: 2-Methoxy-methylbutane (TAME): Acute Toxicity to Bacteria (Pseudomonas putida) | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to microorganisms Right to refer to study -- Title: 2-Methoxy-methylbutane (TAME): Acute Toxicity to Bacteria (Pseudomonas putida) | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Basic toxicokinetics Robust Study Summary -- Title: Biotransformation of MTBE ETBE and TAME after inhalation or ingestion in rats and humans | Author: Dekant W Bernauer U Rosner E Amberg A | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetic study in rats treated with single dose of [14C] ETBE (translation) | Author: Mitsubishi Chemical Safety Institute Ltd | Year: 2008 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetic study in rats treated with [14C] ETBE repeatedly for 14 days (translation) | Author: Mitsubishi Chemical Safety Institute Ltd | Year: 2008 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Robust Study Summary -- Title: Test article: ETBE. Test to evaluate the acute toxicity following a single oral administration (limit test) in the rat. | Author: Pharmakon Europe | Year: 1994 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Right to refer to study -- Title: Test article: ETBE. Test to evaluate the acute toxicity following a single oral administration (limit test) in the rat. | Author: Pharmakon Europe | Year: 1994 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Robust Study Summary -- Title: Etude de toxicite aigue aux doses limites (seion CEE annexe VI J 08-7-92) par voie orale chez le rat: Ether ETBE. | Author: Institut Pasteur de Lille | Year: 1992 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: oral Right to refer to study -- Title: Etude de toxicite aigue aux doses limites (seion CEE annexe VI J 08-7-92) par voie orale chez le rat: Ether ETBE. | Author: Institut Pasteur de Lille | Year: 1992 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: oral Robust Study Summary -- Title: Test article: ethyl tertiary butyl ether; single dose oral toxicity in rats/LD50 in rats | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: oral Right to refer to study -- Title: Test article: ethyl tertiary butyl ether; single dose oral toxicity in rats/LD50 in rats | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: inhalation Robust Study Summary -- Title: Acute inhalation toxicity study of ethyl-t-butyl ether (ETBE) in rats | Author: IIT Research Institute | Year: 1989 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Right to refer to study -- Title: Acute inhalation toxicity study of ethyl-t-butyl ether (ETBE) in rats | Author: IIT Research Institute | Year: 1989 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Acute dermal toxicity study of ethyl-tert-butyl ether (ETBE) in rabbits | Author: IIT Research Institute | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Right to refer to study -- Title: Acute dermal toxicity study of ethyl-tert-butyl ether (ETBE) in rabbits | Author: IIT Research Institute | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Test substance: ethyl tertiary butyl ether; acute dermal toxicity in rabbits/LD50 in rabbits. | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: dermal Right to refer to study -- Title: Test substance: ethyl tertiary butyl ether; acute dermal toxicity in rabbits/LD50 in rabbits. | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Robust Study Summary -- Title: Test article: ETBE. Test to evaluate the acute primary cutaneous irritation and corrosivity in the rabbit (3 animals). | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Right to refer to study -- Title: Test article: ETBE. Test to evaluate the acute primary cutaneous irritation and corrosivity in the rabbit (3 animals). | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: Test substance ethyl tertiary butyl ether. Primary Dermal Irritation in rabbits. | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Right to refer to study -- Title: Test substance ethyl tertiary butyl ether. Primary Dermal Irritation in rabbits. | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Robust Study Summary -- Title: Ether effet irritant aigu sur la peau chez le lapin | Author: Centre International de Toxicologie | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Right to refer to study -- Title: Ether effet irritant aigu sur la peau chez le lapin | Author: Centre International de Toxicologie | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Robust Study Summary -- Title: Test article: ETBE. Test to evaluate the acute ocular irritation and reversibility in the rabbit (3 animals). | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: Test article: ETBE. Test to evaluate the acute ocular irritation and reversibility in the rabbit (3 animals). | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: Ether irritation oculaire aigue chez le lapin | Author: Centre International de Toxicologie | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Right to refer to study -- Title: Ether irritation oculaire aigue chez le lapin | Author: Centre International de Toxicologie | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Robust Study Summary -- Title: Test substance: ethyl tertiary butyl ether; eye irritation in rabbits | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Right to refer to study -- Title: Test substance: ethyl tertiary butyl ether; eye irritation in rabbits | Author: MB Research Laboratories | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin sensitisation Robust Study Summary -- Title: Test article: ETBE. Test to evaluate sensitising potential in the guinea pig.Guinea pig Maximization test | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin sensitisation Right to refer to study -- Title: Test article: ETBE. Test to evaluate sensitising potential in the guinea pig.Guinea pig Maximization test | Author: Pharmakon Europe | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Repeated dose toxicity: oral Robust Study Summary -- Title: Pathology working group review of selected histopathologic changes in the kidneys of rats assigned to toxicology and carcinogenicity studies of ethyl tertiary butyl ether (ETBE) | Author: Research Pathology Associates LLC | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: oral Right to refer to study -- Title: Pathology working group review of selected histopathologic changes in the kidneys of rats assigned to toxicology and carcinogenicity studies of ethyl tertiary butyl ether (ETBE) | Author: Research Pathology Associates LLC | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: Ethyl tertiary butyl ether (ETBE): ninety-day vapor inhalation toxicity study with neurotoxicity evaluations in Fischer 344 rats | Author: Chemical Industry Institute of Toxicology (CIIT) | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Repeated dose toxicity: inhalation Right to refer to study -- Title: Ethyl tertiary butyl ether (ETBE): ninety-day vapor inhalation toxicity study with neurotoxicity evaluations in Fischer 344 rats | Author: Chemical Industry Institute of Toxicology (CIIT) | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: Four-week inhalation toxicity study of ethyl-tert-butyl ether (ETBE) in rats. | Author: IIT Research Institute | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Right to refer to study -- Title: Four-week inhalation toxicity study of ethyl-tert-butyl ether (ETBE) in rats. | Author: IIT Research Institute | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: Health effects of inhaled tertiary amyl methyl ether and ethyl tertiary butyl ether. | Author: White RD Daughtrey WC and Wells MS | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: No information | Author: Ryan BM Ferguson JS Hatoum NS Klan MJ Farmer RG. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Test article: ETBE. Salmonella typhimurium/mammalian microsome plate incorporation assay (Ames test). | Author: Pharmakon Europe | Year: 1994 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Test article: ETBE. Salmonella typhimurium/mammalian microsome plate incorporation assay (Ames test). | Author: Pharmakon Europe | Year: 1994 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Genetic Toxicology: Salmonella typhimurium Reverse Mutation Assay - Ames test | Author: SLOVNAFT VÚRUP a.s | Year: 2006 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Genetic Toxicology: Salmonella typhimurium Reverse Mutation Assay - Ames test | Author: SLOVNAFT VÚRUP a.s | Year: 2006 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Recherche de mutagenicite sur Salmonella typhimurium His selon la technique de BN Ames. | Author: Institut Pasteur de Lille | Year: 1992 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Recherche de mutagenicite sur Salmonella typhimurium His selon la technique de BN Ames. | Author: Institut Pasteur de Lille | Year: 1992 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Salmonella Mutagenicity Tests: V. Results from the testing of 311 chemicals. | Author: Zeiger E Anderson B Haworth S Lawlor T and Mortelmans K | Year: 1992 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Ethyl tertiary butyl ether: mutagenic potential in the CHO/HGPRT forward mutation assay | Author: Bushy Run Research Center | Year: 1995 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Right to refer to study -- Title: Ethyl tertiary butyl ether: mutagenic potential in the CHO/HGPRT forward mutation assay | Author: Bushy Run Research Center | Year: 1995 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Ethyl tertiary butyl ether: in vitro Chromosome aberrations assay in Chinese Hamster Ovary Cells. | Author: Bushy Run Research Center | Year: 1995 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: Ethyl tertiary butyl ether: in vitro Chromosome aberrations assay in Chinese Hamster Ovary Cells. | Author: Bushy Run Research Center | Year: 1995 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Genetic Toxicology: Micronucleus Test. Cytogenetic analysis of human blood lymphocytes in vitro. | Author: SLOVNAFT VÚRUP a.s. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: Genetic Toxicology: Micronucleus Test. Cytogenetic analysis of human blood lymphocytes in vitro. | Author: SLOVNAFT VÚRUP a.s. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Genetic toxicology: DNA damage and repair | Author: SLOVNAFT VÚRUP a.s. | Year: 2006 | Guideline: 482 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in mammalian cells Right to refer to study -- Title: Genetic toxicology: DNA damage and repair | Author: SLOVNAFT VÚRUP a.s. | Year: 2006 | Guideline: 482 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Ethyl tertiary butyl ether: bone marrow micronucleus test in mice | Author: Bushy Run Research Centre | Year: 1995 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Right to refer to study -- Title: Ethyl tertiary butyl ether: bone marrow micronucleus test in mice | Author: Bushy Run Research Centre | Year: 1995 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Micronucleus test of 2-ethoxy-2-methylpropane (ETBE) using bone marrow in rats administered ETBE intraperitoneally (translation) | Author: Japan Bioassay Research Center | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Micronucleus test of 2-ethoxy-2-methylpropane (ETBE) using bone marrow in rats administered ETBE by gavage (translation) | Author: Japan Bioassay Research Center | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Micronucleus test of ETBE using bone marrow of rats of the "13-week toxicity study of 2-ethoxy-2-methylpropane in F344 rats (drinking water study) [preliminary carcinogenicity study]" (translation) | Author: Japan Bioassay Research Center | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Micronucleus test of ETBE using bone marrow of rats of the '13-week toxicity study of 2-ethoxy-2-methylpropane in F344 rats (inhalation study) [preliminary carcinogenicity study]' (translation) | Author: Japan Bioassay Research Center | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Etude de l'activite|genotoxique par la technique du micronucleus chez la souris|sur le produit ether ETBE. | Author: Institut Pasteur de Lille | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Right to refer to study -- Title: Etude de l'activite|genotoxique par la technique du micronucleus chez la souris|sur le produit ether ETBE. | Author: Institut Pasteur de Lille | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Differential genotoxic effects of subchronic exposure to ethyl tertiary butyl ether in the livers of Aldh2 knockout and wild-type mice. | Author: Weng Z Suda M Ohtani K Mei N Kawamoto T Nakajima T Wang RS | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Subchronic exposure to ethyl tertiary butyl ether resulting in genetic damage in Aldh2 knockout mice. | Author: Weng Z Suda M Ohtani K Mei N Kawamoto T Nakajima T Wang RS | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Aldh2 knockout mice were more sensitive to DNA damage in Leukocytes due to ethyl tertiary butyl ether exposure. | Author: Weng Z Suda M Ohtani K Mei N Kawamoto T Nakajima T Wang RS | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Subchronic exposure to ethyl tertiary butyl ether resulting in genetic damage in Aldh2 knockout mice. | Author: Weng Z Suda M Ohtani K Mei N Kawamoto T Nakajima T Wang RS | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicity to reproduction Robust Study Summary -- Title: Ethyl tertiary butyl ether (ETBE) CAS No. 637-92-3: Reproduction/developmental toxicity dose-range finding/probe study by the oral (gavage) route in two strains of rat. | Author: Centre International de Toxicologie | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicity to reproduction Right to refer to study -- Title: Ethyl tertiary butyl ether (ETBE) CAS No. 637-92-3: Reproduction/developmental toxicity dose-range finding/probe study by the oral (gavage) route in two strains of rat. | Author: Centre International de Toxicologie | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicity to reproduction Robust Study Summary -- Title: A one-generation reproduction toxicity study of ETBE in rats (translation) | Author: Safety Research Institute for Chemical Compounds | Year: 2008 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: A one-generation reproductive toxicity study of ethyl tertiary butyl ether in rats | Author: Fujii S Yabe K Furukawa M Matsuura M and Aoyama H | Year: 2010 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -