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CAS 70131-67-8 | Data Package 1 - 10 t/a (Polymers)

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Includes:

Study name Short Description Data Owner
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: XIAMETER PMX-0930 - Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions | Author: Smithers | Year: 2024 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: XIAMETER PMX-0930 - Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions | Author: Smithers | Year: 2024 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute Toxicity Tests of Water Soluble Fractions and Water Accommodated Fractions of Polydimethylsiloxane Fluids with Daphnia magna under Static Exposures | Author: Dow Corning Corporation | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 63148-62-9 | POLYSILOXANES, DI-METHYL)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Acute Toxicity Tests of Water Soluble Fractions and Water Accommodated Fractions of Polydimethylsiloxane Fluids with Daphnia magna under Static Exposures | Author: Dow Corning Corporation | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 63148-62-9 | POLYSILOXANES, DI-METHYL)
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Toxicological | Acute toxicity: oral Robust Study Summary -- Title: An Acute Oral Toxicity Study of XIAMETER™ PMX-0930 Silanol Fluid in Sprague Dawley Rats (Acute Toxic Class) | Author: Charles River Laboratories Ashland | Year: 2024 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: An Acute Oral Toxicity Study of XIAMETER™ PMX-0930 Silanol Fluid in Sprague Dawley Rats (Acute Toxic Class) | Author: Charles River Laboratories Ashland | Year: 2024 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: XIAMETER PMX-0930 Silanol Fluid: Skin Irritation Test (SIT) Using the EpiDerm Skin Model | Author: Institute for In Vitro Sciences | Year: 2023 | Guideline: 439 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: XIAMETER PMX-0930 Silanol Fluid: Skin Irritation Test (SIT) Using the EpiDerm Skin Model | Author: Institute for In Vitro Sciences | Year: 2023 | Guideline: 439 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Guinea Pig Skin Sensitization Study | Author: Toxikon Corporation | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Right to refer to study -- Title: Guinea Pig Skin Sensitization Study | Author: Toxikon Corporation | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Skin Sensitization Study of Dow Corning 2008 Fluid 10cSt using the Guinea Pig Maximization Test | Author: Huntingdon Life Sciences Ltd. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 63148-62-9 | POLYSILOXANES, DI-METHYL)
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Toxicological | Skin sensitisation Right to refer to study -- Title: Skin Sensitization Study of Dow Corning 2008 Fluid 10cSt using the Guinea Pig Maximization Test | Author: Huntingdon Life Sciences Ltd. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 63148-62-9 | POLYSILOXANES, DI-METHYL)
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity Evaluation of Dow Corning 200 Fluid in the Ames Bacterial Assay | Author: Dow Corning | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Mutagenicity Evaluation of Dow Corning 200 Fluid in the Ames Bacterial Assay | Author: Dow Corning | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -