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CAS 75-56-9 - Data Package > 1000 t/a

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Includes:

Product Name Short Description Data Owner
Melting point/freezing point Robust Study Summary - Title: Low-Temperature Heat Capacity and Related Thermodynamic Functions of Propylene Oxide; Author: Oetting FL; Year: 1964; Guideline: 102; Klimisch score: 2 (reliable with restrictions) Consortium
Melting point/freezing point Right to refer to study - Title: Low-Temperature Heat Capacity and Related Thermodynamic Functions of Propylene Oxide; Author: Oetting FL; Year: 1964; Guideline: 102; Klimisch score: 2 (reliable with restrictions) public
Boiling point Robust Study Summary - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 103; Klimisch score: 1 (reliable without restriction) Consortium
Boiling point Right to refer to study - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 103; Klimisch score: 1 (reliable without restriction) Consortium
Density Robust Study Summary - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 109; Klimisch score: 1 (reliable without restriction) Consortium
Density Right to refer to study - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 109; Klimisch score: 1 (reliable without restriction) Consortium
Vapour pressure Robust Study Summary - Title: Determination of hazardous physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 104; Klimisch score: 1 (reliable without restriction) Consortium
Vapour pressure Right to refer to study - Title: Determination of hazardous physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 104; Klimisch score: 1 (reliable without restriction) Consortium
Water solubility Robust Study Summary - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 105; Klimisch score: 1 (reliable without restriction) Consortium
Water solubility Right to refer to study - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 105; Klimisch score: 1 (reliable without restriction) Consortium
Partition coefficient Robust Study Summary - Title: Propylene Oxide: Acute toxicity (Salmo Gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient; Author: Shell Research Ltd.; Year: 1986; Guideline: 107/117; Klimisch score: 2 (reliable with restrictions) Consortium
Partition coefficient Right to refer to study - Title: Propylene Oxide: Acute toxicity (Salmo Gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient; Author: Shell Research Ltd.; Year: 1986; Guideline: 107/117; Klimisch score: 2 (reliable with restrictions) Shell
Flash point Robust Study Summary - Title: Determination of hazardous physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: ; Klimisch score: 1 (reliable without restriction) Consortium
Flash point Right to refer to study - Title: Determination of hazardous physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: ; Klimisch score: 1 (reliable without restriction) POPG Consortium
Skin irritation / corrosion Robust Study Summary - Title: propylene oxide: in vitro skin corrosion in the Episkin reconstituted human epidermis model; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 404; Klimisch score: 1 (reliable without restriction) Consortium
Skin irritation / corrosion Right to refer to study - Title: propylene oxide: in vitro skin corrosion in the Episkin reconstituted human epidermis model; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 404; Klimisch score: 1 (reliable without restriction) Consortium
eye irritation assessment Robust Study Summary - Title: Chemical burns of the rabbit cornea.; Author: Carpenter CP and Smyth HF Jr.; Year: 1946; Guideline: ; Klimisch score: 3 Consortium
eye irritation assessment Right to refer to study - Title: Chemical burns of the rabbit cornea.; Author: Carpenter CP and Smyth HF Jr.; Year: 1946; Guideline: ; Klimisch score: 3 public
Skin sensitisation Robust Study Summary - Title: Propylene Oxide: Skin Sensitization Potential; Author: Dow Chemical Company; Year: 1982; Guideline: 406, 429; Klimisch score: 2 (reliable with restrictions) Consortium
Skin sensitisation Right to refer to study - Title: Propylene Oxide: Skin Sensitization Potential; Author: Dow Chemical Company; Year: 1982; Guideline: 406, 429; Klimisch score: 2 (reliable with restrictions) Dow
Genetic toxicity in vitro Robust Study Summary - Title: Short-term mutation test with industrial chemicals: propylene oxide. ; Author: Shell Research Ltd.; Year: 1976; Guideline: 471; Klimisch score: 2 (reliable with restrictions) Consortium
Genetic toxicity in vitro Right to refer to study - Title: Short-term mutation test with industrial chemicals: propylene oxide. ; Author: Shell Research Ltd.; Year: 1976; Guideline: 471; Klimisch score: 2 (reliable with restrictions) Shell
in vitro gene mutation study in bacteria (Ames) Robust Study Summary - Title: Comparative mutagenicity of aliphatic epoxides in Salmonella; Author: Canter DA, Zeiger E., Haworth S., Lawlor T, Mortelmans K and Speck W; Year: 1986; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
in vitro gene mutation study in bacteria (Ames) Right to refer to study - Title: Comparative mutagenicity of aliphatic epoxides in Salmonella; Author: Canter DA, Zeiger E., Haworth S., Lawlor T, Mortelmans K and Speck W; Year: 1986; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Acute toxicity: oral Robust Study Summary - Title: A collaborative exercise in acute oral toxicity testing; Author: Shell Research Ltd.; Year: 1968; Guideline: 420, 423, 425; Klimisch score: 2 (reliable with restrictions) Consortium
Acute toxicity: oral Right to refer to study - Title: A collaborative exercise in acute oral toxicity testing; Author: Shell Research Ltd.; Year: 1968; Guideline: 420, 423, 425; Klimisch score: 2 (reliable with restrictions) Shell
Short-term toxicity to aquatic invertebrates Robust Study Summary - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 202; Klimisch score: 2 (reliable with restrictions) Consortium
Short-term toxicity to aquatic invertebrates Right to refer to study - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 202; Klimisch score: 2 (reliable with restrictions) Shell
Short-term toxicity to fish Robust Study Summary - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 203; Klimisch score: 2 (reliable with restrictions) Consortium
Short-term toxicity to fish Right to refer to study - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 203; Klimisch score: 2 (reliable with restrictions) Shell
Biodegradation in water: screening tests Robust Study Summary - Title: Biodegradation and bioaccumulation testing results on existing chemical substances. ; Author: MITI (Ministry of International Trade and Industry) Japan; Year: 1988; Guideline: 301C; Klimisch score: 2 (reliable with restrictions) Consortium
Biodegradation in water: screening tests Right to refer to study - Title: Biodegradation and bioaccumulation testing results on existing chemical substances. ; Author: MITI (Ministry of International Trade and Industry) Japan; Year: 1988; Guideline: 301C; Klimisch score: 2 (reliable with restrictions) Japan MITI
Genetic toxicity in vitro Robust Study Summary - Title: Short-term mutation test with industrial chemicals: propylene oxide. ; Author: Shell Research Ltd.; Year: 1976; Guideline: 473, 485; Klimisch score: 2 (reliable with restrictions) Consortium
Genetic toxicity in vitro Right to refer to study - Title: Short-term mutation test with industrial chemicals: propylene oxide. ; Author: Shell Research Ltd.; Year: 1976; Guideline: 473, 485; Klimisch score: 2 (reliable with restrictions) Shell
Genetic toxicity in vitro Robust Study Summary - Title: Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapours. ; Author: McGregor D, Brown AG, Cattanach P, Edwards I, McBride D, Riach C, Shepherd W, Caspary WJ; Year: 1991; Guideline: 476, 474, 475; Klimisch score: 2 (reliable with restrictions) Consortium
Genetic toxicity in vitro Right to refer to study - Title: Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapours. ; Author: McGregor D, Brown AG, Cattanach P, Edwards I, McBride D, Riach C, Shepherd W, Caspary WJ; Year: 1991; Guideline: 476, 474, 475; Klimisch score: 2 (reliable with restrictions) public
in vitro gene mutation study in bacteria (Ames) Robust Study Summary - Title: Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals.; Author: Gulati DK, Witt K, Anderson B, Zeiger E, Shelby MD; Year: 1989; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
in vitro gene mutation study in bacteria (Ames) Right to refer to study - Title: Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals.; Author: Gulati DK, Witt K, Anderson B, Zeiger E, Shelby MD; Year: 1989; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Acute toxicity: inhalation Robust Study Summary - Title: Toxicity studies on propyle oxide: acute inhalation toxicity and 10 day repeated exposure study; Author: Shell Research Ltd.; Year: 1977; Guideline: 403; Klimisch score: 2 (reliable with restrictions) Consortium
Acute toxicity: inhalation Right to refer to study - Title: Toxicity studies on propyle oxide: acute inhalation toxicity and 10 day repeated exposure study; Author: Shell Research Ltd.; Year: 1977; Guideline: 403; Klimisch score: 2 (reliable with restrictions) Shell
Acute toxicity: dermal Robust Study Summary - Title: Range finding toxicity data. (List VII).; Author: Smyth HF, Carpenter CP, Weil CS, Pozzani US, Striegel JA and Nycum JS.; Year: 1969; Guideline: 402; Klimisch score: 2 (reliable with restrictions) Consortium
Acute toxicity: dermal Right to refer to study - Title: Range finding toxicity data. (List VII).; Author: Smyth HF, Carpenter CP, Weil CS, Pozzani US, Striegel JA and Nycum JS.; Year: 1969; Guideline: 402; Klimisch score: 2 (reliable with restrictions) public
Repeated dose toxicity: inhalation Robust Study Summary - Title: chronic (28-month) inhalation toxicity/carcinogenicity study of 1, 2-propylene oxide in rats; Author: TNO; Year: 1984; Guideline: 407, 410, 412; Klimisch score: 1 (reliable without restriction) Consortium
Repeated dose toxicity: inhalation Right to refer to study - Title: chronic (28-month) inhalation toxicity/carcinogenicity study of 1, 2-propylene oxide in rats; Author: TNO; Year: 1984; Guideline: 407, 410, 412; Klimisch score: 1 (reliable without restriction) Joint Industry Committee on Propylene Oxide
Hydrolysis Robust Study Summary - Title: Chemicals of current interest. Propylene oxide: health and environmental effects profile ; Author: Meylan W, Papa L, De Rosa CT and Stara JF ; Year: 1986; Guideline: 111; Klimisch score: 2 (reliable with restrictions) Consortium
Hydrolysis Right to refer to study - Title: Chemicals of current interest. Propylene oxide: health and environmental effects profile ; Author: Meylan W, Papa L, De Rosa CT and Stara JF ; Year: 1986; Guideline: 111; Klimisch score: 2 (reliable with restrictions) public
Viscosity Robust Study Summary - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 114; Klimisch score: 1 (reliable without restriction) Consortium
Viscosity Right to refer to study - Title: Determination of general physico-chemical properties; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 114; Klimisch score: 1 (reliable without restriction) Consortium
Genetic toxicity in vivo Robust Study Summary - Title: Effects of inhaled prolyene oxide an nasal cell proliferation biomarkers of exposure, and DNA lesions in male Fischer 344 rats abd B6C3F1 mice. Phase 1 Inhalation exposure, in-life observations, necropsy, tissue sample isolation ; Author: Dow Chemical Company; Year: 2009; Guideline: 486; Klimisch score: 2 (reliable with restrictions) Consortium
Genetic toxicity in vivo Right to refer to study - Title: Effects of inhaled prolyene oxide an nasal cell proliferation biomarkers of exposure, and DNA lesions in male Fischer 344 rats abd B6C3F1 mice. Phase 1 Inhalation exposure, in-life observations, necropsy, tissue sample isolation ; Author: Dow Chemical Company; Year: 2009; Guideline: 486; Klimisch score: 2 (reliable with restrictions) TWO owners: ACC PO/PG Panel and Propylene oxide and Glycols sector Group Cefic
Cytogenicitic assay / chromosomal abberation test (in vivo) Robust Study Summary - Title: Sister-chromatid exchanges and chromosome aberrations in lymphocytes from monkeys exposed to ethylene oxide and propylene oxide by inhalation.; Author: Lynch DW, Lewis TR, Moorman WJ, Burg JR, Gulati DK, Kaur P and Sabharwal PS; Year: 1984; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
Cytogenicitic assay / chromosomal abberation test (in vivo) Right to refer to study - Title: Sister-chromatid exchanges and chromosome aberrations in lymphocytes from monkeys exposed to ethylene oxide and propylene oxide by inhalation.; Author: Lynch DW, Lewis TR, Moorman WJ, Burg JR, Gulati DK, Kaur P and Sabharwal PS; Year: 1984; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Cytogenicitic assay / chromosomal abberation test (in vivo) Robust Study Summary - Title: Genotoxic effects of inhaled ethylene oxide, propylene oxide and butylene oxide on germ cells: sensitivity of genetic endpoints in relation to dose and repair status; Author: Vogel EW and Nivard MJ; Year: 1988; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
Cytogenicitic assay / chromosomal abberation test (in vivo) Right to refer to study - Title: Genotoxic effects of inhaled ethylene oxide, propylene oxide and butylene oxide on germ cells: sensitivity of genetic endpoints in relation to dose and repair status; Author: Vogel EW and Nivard MJ; Year: 1988; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Cytogenicitic assay / chromosomal abberation test (in vivo) Robust Study Summary - Title: The response of germ cell s to Ethylene oxide , propylene oxide, propylene imine and methyl methanesulfonate is a matter of cell stage-related DNArepair.; Author: Vogel EW and Nivard MJ; Year: 1997; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
Cytogenicitic assay / chromosomal abberation test (in vivo) Right to refer to study - Title: The response of germ cell s to Ethylene oxide , propylene oxide, propylene imine and methyl methanesulfonate is a matter of cell stage-related DNArepair.; Author: Vogel EW and Nivard MJ; Year: 1997; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Cytogenicitic assay / chromosomal abberation test (in vivo) Robust Study Summary - Title: Mutagenic activity of propylene oxide in bacterial and mammalian systems; Author: Bootman J, Lodge DC and Whalley HE; Year: 1979; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
Cytogenicitic assay / chromosomal abberation test (in vivo) Right to refer to study - Title: Mutagenic activity of propylene oxide in bacterial and mammalian systems; Author: Bootman J, Lodge DC and Whalley HE; Year: 1979; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Cytogenicitic assay / chromosomal abberation test (in vivo) Robust Study Summary - Title: Propylene oxide: Genotoxicity profile of a rodent nasal carcinogen; Author: Albertini RJ and Sweeney LM; Year: 2007; Guideline: ; Klimisch score: 2 (reliable with restrictions) Consortium
Cytogenicitic assay / chromosomal abberation test (in vivo) Right to refer to study - Title: Propylene oxide: Genotoxicity profile of a rodent nasal carcinogen; Author: Albertini RJ and Sweeney LM; Year: 2007; Guideline: ; Klimisch score: 2 (reliable with restrictions) public
Toxicity to aquatic algae and cyanobacteria Robust Study Summary - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 221; Klimisch score: 2 (reliable with restrictions) Consortium
Toxicity to aquatic algae and cyanobacteria Right to refer to study - Title: Propylene oxide: acute toxicity (Salmo gairdneri, Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient ; Author: Shell Research Ltd.; Year: 1986; Guideline: 221; Klimisch score: 2 (reliable with restrictions) Shell
Toxicity to microorganisms Robust Study Summary - Title: Activated sludge respiration inhibition test Project Nr. 2972/0005; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 209; Klimisch score: 2 (reliable with restrictions) Consortium
Toxicity to microorganisms Right to refer to study - Title: Activated sludge respiration inhibition test Project Nr. 2972/0005; Author: Harlan Laboratories Ltd.; Year: 2010; Guideline: 209; Klimisch score: 2 (reliable with restrictions) Consortium - not feasable to perform study
Developmental toxicity / teratogenicity Robust Study Summary - Title: Inhalation developmental toxicity study in rats; Author: International Research and Development Corporation; Year: 1987; Guideline: 414; Klimisch score: 1 (reliable without restriction) Consortium
Developmental toxicity / teratogenicity Right to refer to study - Title: Inhalation developmental toxicity study in rats; Author: International Research and Development Corporation; Year: 1987; Guideline: 414; Klimisch score: 1 (reliable without restriction) two dataowner: LyondellBasell & Dow
Toxicity to reproduction Robust Study Summary - Title: Propylene oxide: two-generation inhalation reproduction study in Fischer 344 Rats; Author: Dow Chemical Company; Year: 1985; Guideline: 416; Klimisch score: 1 (reliable without restriction) Consortium
Toxicity to reproduction Right to refer to study - Title: Propylene oxide: two-generation inhalation reproduction study in Fischer 344 Rats; Author: Dow Chemical Company; Year: 1985; Guideline: 416; Klimisch score: 1 (reliable without restriction) "three data owners: LyondellBasell, DOW, Shell"
Carcinogenicity Robust Study Summary - Title: chronic (28-month) inhalation toxicity/carcinogenicity study of 1, 2-propylene oxide in rats; Author: TNO; Year: 1984; Guideline: 451; Klimisch score: 1 (reliable without restriction) Consortium
Carcinogenicity Right to refer to study - Title: chronic (28-month) inhalation toxicity/carcinogenicity study of 1, 2-propylene oxide in rats; Author: TNO; Year: 1984; Guideline: 451; Klimisch score: 1 (reliable without restriction) Joint Industry Committee on Propylene Oxide
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