You are here: Home> South Korea>K-REACH>CAS 75-78-5> CAS 75-78-5 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physical Properties Database | Author: AIChE | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physical Properties Database | Author: AIChE | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | trimethoxy(methyl)silane) |
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| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | trimethoxy(methyl)silane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol) |
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| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 90-day inhalation toxicity study of hydrogen chloride gas in B6C3F1 mice, Sprague-Dawley rats and Fischer-344 rats. | Author: Toxigenics Inc | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 7647-01-0 | EC 231-595-7 | Hydrogen chloride) |
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