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CAS 75-79-6 | Data Package 10 - 100 t/a

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Includes:

Study name Short Description Data Owner
Explosive properties Robust Study Summary -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Explosive properties Right to refer to study -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Robust Study Summary -- Title: An Acute Whole Body Inhalation Toxicity Study of Methyltrichlorosilane in Fischer 344 Rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Right to refer to study -- Title: An Acute Whole Body Inhalation Toxicity Study of Methyltrichlorosilane in Fischer 344 Rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: Design Institute for Physical Property Data (DIPPR) | Author: American Institute of Chemical Engineers (AIChE) | Year: 1946 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Trichloromethylsilane salmonella/microsome test to evaluate for point mutagenic effects | Author: Bayer AG | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Trichloromethylsilane salmonella/microsome test to evaluate for point mutagenic effects | Author: Bayer AG | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Mutagenicity evaluation of Methyltrichlorosilane | Author: Litton Bionetics | Year: 1978 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: Organochlorosilane A-154 Primary Skin Irritancy Study in the Rabbit. | Author: Myers R C, Christopher S M | Year: 1989 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin irritation / corrosion Right to refer to study -- Title: Organochlorosilane A-154 Primary Skin Irritancy Study in the Rabbit. | Author: Myers R C, Christopher S M | Year: 1989 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: Design Institute for Physical Property Data (DIPPR) | Author: American Institute of Chemical Engineers (AIChE) | Year: 2003 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Weast, R. C. (ed.) | Year: 1988 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Robust Study Summary -- Title: Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silcones Health Council | Year: 1987 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Right to refer to study -- Title: Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silcones Health Council | Year: 1987 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: BRRC | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: BRRC | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Mutagenicity evaluation of Methyltrichlorosilane | Author: Litton Bionetics | Year: 1978 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity Evaluation of methyltrichlorosilane MeSiCl3 | Author: Litton Bonetics | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Appearance/physical state/colour Robust Study Summary -- Title: Methyl Trichlorosilane and its Fluorination Products. | Author: Booth H S, Martin W F III | Year: 1946; 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Appearance/physical state/colour Right to refer to study -- Title: Methyl Trichlorosilane and its Fluorination Products. | Author: Booth H S, Martin W F III | Year: 1946; 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Robust Study Summary -- Title: The Sigma Aldrich Library of Chemical Safety Data, | Author: Sigma Aldrich | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: oral Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies. | Author: BRRC | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: oral Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies. | Author: BRRC | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: BRRC | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: BRRC | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Assessment of Ready Biodegradability. CO2 in Sealed Vessels (CO2 Headspace Test) | Year: 2008 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Assessment of Ready Biodegradability. CO2 in Sealed Vessels (CO2 Headspace Test) | Year: 2008 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Jean PA | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Jean PA | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Jean PA | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Jean PA | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Methyltrimethoxysilane: Freshwater Algal, Pseudokirchneriella subcapitata, Growth Inhibition Test | Author: Dow Corning | Year: 2007 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Methyltrimethoxysilane: Freshwater Algal, Pseudokirchneriella subcapitata, Growth Inhibition Test | Author: Dow Corning | Year: 2007 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish) | Author: Hazleton | Year: 1994; 1997 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish) | Author: Hazleton | Year: 1994; 1997 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Water solubility Waiver -
Partition coefficient Robust Study Summary -- Title: KOWWIN v. 1.67a; USEPA; other:; Atom/fragment contribution method for estimating octanol-water partition coefficients; Reconsile REACH Registration: Background to property prediction for Partition coefficient n-octanol/water Reconsile; | Author: Meylan WM and Howard PH; Peter Fisk Associates | Year: 2009; 1995; 2009 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Partition coefficient Right to refer to study -- Title: KOWWIN v. 1.67a; USEPA; other:; Atom/fragment contribution method for estimating octanol-water partition coefficients; Reconsile REACH Registration: Background to property prediction for Partition coefficient n-octanol/water Reconsile; | Author: Meylan WM and Howard PH; Peter Fisk Associates | Year: 2009; 1995; 2009 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: A two-week repeated dose inhalation toxicity study of hydrogen chloride and selected chlorosilanes in albino rats. ; study report; | Author: Dow Corning Corporation | Year: 1993 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Repeated dose toxicity: inhalation Right to refer to study -- Title: A two-week repeated dose inhalation toxicity study of hydrogen chloride and selected chlorosilanes in albino rats. ; study report; | Author: Dow Corning Corporation | Year: 1993 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Genetic toxicity in vivo Robust Study Summary -- Title: The effect of methyltrichlorosilane on the incidence of chromosome breaks and aberrations in rat bone marrow cells; study report; Bioassay Systems Corporation | Author: Gerlach R; IHF | Year: 1982 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -