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CAS 78-10-4 | Data Package 10 - 100 t/a

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Study name Short Description Data Owner
Hydrolysis Robust Study Summary -- Title: The Hydrolysis of Tetraethoxysilane (CAS# 78-10-4); | Author: Dow Corning Corporation | Year: 2003 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Hydrolysis Right to refer to study -- Title: The Hydrolysis of Tetraethoxysilane (CAS# 78-10-4); | Author: Dow Corning Corporation | Year: 2003 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: In Vitro Mammalian Chromosome Aberration Test. Test article Tetraethyl orthosilicate CAS 87-10-4 | Author: Gudi R, Brown C | Year: 2002 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: In Vitro Mammalian Chromosome Aberration Test. Test article Tetraethyl orthosilicate CAS 87-10-4 | Author: Gudi R, Brown C | Year: 2002 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: Test for acute eye and mucous membrane tissue irritation by DYNASIL A in rabbits | Author: Degussa-Huls AG | Year: 1992 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: Test for acute eye and mucous membrane tissue irritation by DYNASIL A in rabbits | Author: Degussa-Huls AG | Year: 1992 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Tetraethyl Orthosilicate: Combined Repeated Dose Toxicity Study with Reproductive/Developmental Toxicity Screening Test | Author: CIT Safety & Health Research Laboratories | Year: 2002 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Right to refer to study -- Title: Tetraethyl Orthosilicate: Combined Repeated Dose Toxicity Study with Reproductive/Developmental Toxicity Screening Test | Author: CIT Safety & Health Research Laboratories | Year: 2002 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Ethyl Silicate -Acute Toxicity to Water Fleas, (Daphnia magna) Under Flow-Through Conditions | Author: Springborn Smithers Laboratories | Year: 2006 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Ethyl Silicate -Acute Toxicity to Water Fleas, (Daphnia magna) Under Flow-Through Conditions | Author: Springborn Smithers Laboratories | Year: 2006 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Ethyl Silicate -Acute Toxicity to the Freshwater Green Alga, Pseudokirchneriella subcapitata | Author: Springborn Laboratories, Inc., | Year: 2006 | Guideline: 221 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Ethyl Silicate -Acute Toxicity to the Freshwater Green Alga, Pseudokirchneriella subcapitata | Author: Springborn Laboratories, Inc., | Year: 2006 | Guideline: 221 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: Test for skin irritation by DYNASYL A In rabbits | Author: Degussa-Huls AG | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Right to refer to study -- Title: Test for skin irritation by DYNASYL A In rabbits | Author: Degussa-Huls AG | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1) | Author: Hüls AG | Year: 1993 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Right to refer to study -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1) | Author: Hüls AG | Year: 1993 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Determination of the biodegradability of DYNASIL A In DOC-DIE AWAY TEST | Author: Schoeberl | Year: 1993 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Determination of the biodegradability of DYNASIL A In DOC-DIE AWAY TEST | Author: Schoeberl | Year: 1993 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Robust Study Summary -- Title: SPLG 396 Acute oral toxicity study in male and female Wistar rats | Author: Krotlinger, F | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: oral Right to refer to study -- Title: SPLG 396 Acute oral toxicity study in male and female Wistar rats | Author: Krotlinger, F | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Robust Study Summary -- Title: Test of the acute toxicity of the inhaled aerosol content of Wacker Ethyl Silicate TES 28 in male and female SPF Wistar rats- 4 hours, LC50 | Author: Hoechst | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Right to refer to study -- Title: Test of the acute toxicity of the inhaled aerosol content of Wacker Ethyl Silicate TES 28 in male and female SPF Wistar rats- 4 hours, LC50 | Author: Hoechst | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Boiling point Robust Study Summary -- Title: The Merck index, 12th Edition | Author: Budavari S. | Year: 1996 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Robust Study Summary -- Title: Saftey Data Sheet Dynasylan A | Author: Evonik | Year: 2007 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Appearance/physical state/colour Robust Study Summary -- Title: Handbook of Chemistry and Physics. 64th ed. | Author: Weast R.C.; Budavari S. | Year: 1983; 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Appearance/physical state/colour Right to refer to study -- Title: Handbook of Chemistry and Physics. 64th ed. | Author: Weast R.C.; Budavari S. | Year: 1983; 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Robust Study Summary -- Title: Saftey Data Sheet Dynasylan A EC 1907 / 2006 | Author: Evonik | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Determination of mutations caused by DYNASIL A In Salmonella/microsome test based on Ames mutation test under Guideline 84/449/EEC B. 14. Certified translation from German; | Author: Schroeberl; Huls AG | Year: 1993 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Determination of mutations caused by DYNASIL A In Salmonella/microsome test based on Ames mutation test under Guideline 84/449/EEC B. 14. Certified translation from German; | Author: Schroeberl; Huls AG | Year: 1993 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Tetraethyl orthosilicates: in vitro mutagenesis studies | Author: Slesinski RS et al. | Year: 1981 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Right to refer to study -- Title: Tetraethyl orthosilicates: in vitro mutagenesis studies | Author: Slesinski RS et al. | Year: 1981 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin sensitisation Robust Study Summary -- Title: Test for skin sensitization by DYNASIL A In guinea pigs.; | Author: Degussa-Huls AG | Year: 1992 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin sensitisation Right to refer to study -- Title: Test for skin sensitization by DYNASIL A In guinea pigs.; | Author: Degussa-Huls AG | Year: 1992 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: Handbook of Chemistry and Physics. 64th ed | Author: Weast R.C. | Year: 1983 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: Handbook of Chemistry and Physics. 64th ed | Author: Weast R.C. | Year: 1983 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: No-effect level of subacute tetraethoxysilane inhalation on the mouse kidney | Author: Omae K et al. | Year: 1995 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Safety of the metal scavengers sodium metasilicate and sodium polyphosphate. Soluble Silicates. CAS No. 1344-09-8, 6834-92-0, 10213-79-3, 13517-24-3 and 1312-76-1.; OECD SIDS | Author: Saiwai, K. et al. | Year: 1980; 2004 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: QMRF for QSAR model for the prediction of the vapour pressure of organosillicon compounds; QPRF for Tetraethyl orthosilicate using the QSAR model for the prediction of the vapour pressure of organosilicon compounds; | Author: Peter Fisk Associates | Year: 2009; 2009 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Right to refer to study -- Title: QMRF for QSAR model for the prediction of the vapour pressure of organosillicon compounds; QPRF for Tetraethyl orthosilicate using the QSAR model for the prediction of the vapour pressure of organosilicon compounds; | Author: Peter Fisk Associates | Year: 2009; 2009 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Partition coefficient Robust Study Summary -- Title: Partition Coefficient (Cas 78-10-4) | Author: Altmann S | Year: 2001 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Partition coefficient Right to refer to study -- Title: Partition Coefficient (Cas 78-10-4) | Author: Altmann S | Year: 2001 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Robust Study Summary -- Title: ANNEX TO ETHYL SILICATE ROBUST SUMMARIES, CAS NO. 78-10-4 | Author: Dr Altmann. S. | Year: 2002 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Right to refer to study -- Title: ANNEX TO ETHYL SILICATE ROBUST SUMMARIES, CAS NO. 78-10-4 | Author: Dr Altmann. S. | Year: 2002 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Robust Study Summary -- Title: The Hydrolysis of Tetraethoxysilane (CAS# 78-10-4) | Author: Dow Corning Corporation | Year: 2003 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Right to refer to study -- Title: The Hydrolysis of Tetraethoxysilane (CAS# 78-10-4) | Author: Dow Corning Corporation | Year: 2003 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: inhalation Robust Study Summary -- Title: Test of the acute toxicity of the inhaled aerosol content of Wacker Ethyl Silicate TES 40 in male and female SPF Wistar rats- 4 hours, LC50. | Author: Hoechst | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Acute toxicity: inhalation Right to refer to study -- Title: Test of the acute toxicity of the inhaled aerosol content of Wacker Ethyl Silicate TES 40 in male and female SPF Wistar rats- 4 hours, LC50. | Author: Hoechst | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Acute toxicity: inhalation Robust Study Summary -- Title: Acute and subchronic inhalation toxicity of tetraethoxysilane (TEOS) in mice. | Author: Nakashima H et al. | Year: 1994 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Robust Study Summary -- Title: Wacker Ethylsilikat TES 28 Prufung auf Augenreizung am Kaninchen; | Author: Hoechst | Year: 1991 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eye irritation Right to refer to study -- Title: Wacker Ethylsilikat TES 28 Prufung auf Augenreizung am Kaninchen; | Author: Hoechst | Year: 1991 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eye irritation Robust Study Summary -- Title: Summary of the Acute Response of Guinea Pigs and Rats to Inhalation of the Vapors of Tetraethyl Orthosilicate; | Author: Smyth, HF | Year: 1940 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -