You are here: Home> Taiwan>TW-REACH>CAS 872-50-4> CAS 872-50-4 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Appearance/physical state/colour | Robust Study Summary -- Title: Analytical Report - Characterization of N-Methylpyrrolidon for toxicological studies | Author: BASF AG | Year: 1997 | Klimisch score: 1 - Reliable without restriction. | - |
| Appearance/physical state/colour | Right to refer to study -- Title: Analytical Report - Characterization of N-Methylpyrrolidon for toxicological studies | Author: BASF AG | Year: 1997 | Klimisch score: 1 - Reliable without restriction. | - |
| Melting point/freezing point | Robust Study Summary -- Title: Schmelzpunkt von 1-Methylpyrrolidon- 2 | Author: BASF AG | Year: 1984 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Melting point/freezing point | Right to refer to study -- Title: Schmelzpunkt von 1-Methylpyrrolidon- 2 | Author: BASF AG | Year: 1984 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Boiling point | Robust Study Summary -- Title: Dampfdruck und Verdampfungsenthalpie von 1-Methylpyrrolidon-2 | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions. | - |
| Boiling point | Right to refer to study -- Title: Dampfdruck und Verdampfungsenthalpie von 1-Methylpyrrolidon-2 | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions. | - |
| Density | Robust Study Summary -- Title: Physical Properties of Aqueous N-Methyl Pyrrolidone at Different Temperatures | Author: Maloka IE and Ibrahim SY | Year: 2004 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Vapour pressure | Robust Study Summary -- Title: Dampfdruck 1-METHYL-2-PYRROLIDON | Author: BASF AG | Year: 1989 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions. | - |
| Vapour pressure | Right to refer to study -- Title: Dampfdruck 1-METHYL-2-PYRROLIDON | Author: BASF AG | Year: 1989 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions. | - |
| Water solubility | Robust Study Summary -- Title: Techniques of Chemistry. Volume 2: Organic Solvents. 4th edition | Author: Riddick JA Bunger WB and Sakano TK | Year: 1986 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Partition coefficient | Robust Study Summary -- Title: Bestimmung des Verteilungskoeffizienten Pow von N-Methylpyrrolidon in 1-Octanol/Wasser bei Raumtemperatur (25 °C) | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions. | - |
| Partition coefficient | Right to refer to study -- Title: Bestimmung des Verteilungskoeffizienten Pow von N-Methylpyrrolidon in 1-Octanol/Wasser bei Raumtemperatur (25 °C) | Author: BASF AG | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions. | - |
| Flash point | Robust Study Summary -- Title: Sicherheitstechnische Kenndaten | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions. | - |
| Flash point | Right to refer to study -- Title: Sicherheitstechnische Kenndaten | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions. | - |
| Auto-ignition temperature | Robust Study Summary -- Title: Sicherheitstechnische Kenndaten | Author: BASF AG | Year: 2018 | Klimisch score: 2 - Reliable with restrictions. | - |
| Auto-ignition temperature | Right to refer to study -- Title: Sicherheitstechnische Kenndaten | Author: BASF AG | Year: 2018 | Klimisch score: 2 - Reliable with restrictions. | - |
| Viscosity | Robust Study Summary -- Title: Physical Properties of Aquaeous N-Methyl Pyrrolidone at Different Temperatures | Author: Maloka IE and Ibrahim SY | Year: 2004 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Skin irritation / corrosion | Robust Study Summary -- Title: Skin irritation (indicate if in vitro) | Author: Ansell & Fowler JA/Fd | Year: 1988 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction. | Consortium |
| Eye irritation | Robust Study Summary -- Title: Eye irritation (indicate if in vitro) | Author: Ansell & Fowler JA/Fd | Year: 1988 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Skin sensitisation | Robust Study Summary -- Title: Skin sensitisation | Year: 2005 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions. | - |
| Skin sensitisation | Right to refer to study -- Title: Skin sensitisation | Year: 2005 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions. | - |
| in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity test: II. Results from the testing of 270 chemicals | Author: Mortelmans K. Haworth S. Lawlor T. Speck W. Tainer B. Zeiger E. | Year: 1986 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Chemical Effects in Biological Systems (CEBS): N-Methyl-2-pyrrolidone | Author: National Institute of Environmental Health Sciences | Year: 2015 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Ames test for N-methylpyrrolidone | Author: BASF AG Department of Toxicology | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions. | - |
| in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Ames test for N-methylpyrrolidone | Author: BASF AG Department of Toxicology | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions. | - |
| Genetic toxicity in vivo | Robust Study Summary -- Title: 1-Methyl-2-pyrrolidone (NMP)|does not induce structural and numerical chromosomal aberrations in vivo | Author: Engelhardt G. Fleig H. | Year: 1993 | Guideline: 475 | Klimisch score: 1 - Reliable without restriction. | Consortium |
| Genetic toxicity in vivo | Robust Study Summary -- Title: Cytogenetic study in vivo of N-methylpyrrolidone in mice micronucleus test single oral administration | Author: BASF AG Department of Toxicology | Year: 1989 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction. | - |
| Genetic toxicity in vivo | Right to refer to study -- Title: Cytogenetic study in vivo of N-methylpyrrolidone in mice micronucleus test single oral administration | Author: BASF AG Department of Toxicology | Year: 1989 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction. | - |
| Acute toxicity: oral | Robust Study Summary -- Title: The acute oral toxicity and primary ocular and dermal irritation of selected N-alkyl-2-pyrrolidones | Author: Ansell JM & Fowler JA | Year: 1988 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Acute toxicity: inhalation | Robust Study Summary -- Title: Evaluation in rats of acute inhalation toxicity (LC50) of N-methylpyrrolidone as an aerosol liquid. Four-hour exposure | Author: BASF AG | Year: 1988 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction. | - |
| Acute toxicity: inhalation | Right to refer to study -- Title: Evaluation in rats of acute inhalation toxicity (LC50) of N-methylpyrrolidone as an aerosol liquid. Four-hour exposure | Author: BASF AG | Year: 1988 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction. | - |
| Acute toxicity: dermal | Robust Study Summary -- Title: Dermal toxicity of dimethyl acetylene dicarboxylate N-methyl pyrrolidone triethylene glycol dimethyl ether dioxane and tetralin in the rat | Author: Clark B Furlong JW Ladner A & Slovak AJM | Year: 1984 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Repeated dose toxicity: oral | Robust Study Summary -- Title: Subchronic oral toxicity: 28-day feeding study in rats with N-methylpyrrolidone (NMP) | Author: Haskell laboratories | Year: 1994 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: oral | Right to refer to study -- Title: Subchronic oral toxicity: 28-day feeding study in rats with N-methylpyrrolidone (NMP) | Author: Haskell laboratories | Year: 1994 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: oral | Robust Study Summary -- Title: Subchronic oral toxicity: 90-day feeding and neurotoxicity study in rats with N-methylpyrrolidone (NMP) | Author: Haskell Laboratory | Year: 1995 | Guideline: 408 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: oral | Right to refer to study -- Title: Subchronic oral toxicity: 90-day feeding and neurotoxicity study in rats with N-methylpyrrolidone (NMP) | Author: Haskell Laboratory | Year: 1995 | Guideline: 408 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Study on the inhalation toxicity of N-methylpyrrolidon as a liquid aerosol in rats - 90-day-test including an about 4-week post-exposure observation period | Author: BASF AG | Year: 1994 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: inhalation | Right to refer to study -- Title: Study on the inhalation toxicity of N-methylpyrrolidon as a liquid aerosol in rats - 90-day-test including an about 4-week post-exposure observation period | Author: BASF AG | Year: 1994 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction. | - |
| Repeated dose toxicity: oral | Robust Study Summary -- Title: | Guideline: 408. | - |
| Repeated dose toxicity: oral | Right to refer to study -- Title: | Guideline: 408. | - |
| Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity of N-methyl-2-pyrrolidone administered by gavage or inhalation to rats. | Author: Saillenfait AM et al. | Year: 2001 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction. | Consortium |
| Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Study of the prenatal toxicity of N-Methylpyrrolidon in rabbits after inhalation of vapor-aerosol-mi… | Year: 1993 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction. | - |
| Developmental toxicity/teratogenicity | Right to refer to study -- Title: Study of the prenatal toxicity of N-Methylpyrrolidon in rabbits after inhalation of vapor-aerosol-mi… | Year: 1993 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction. | - |
| Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity study, rabbits, | Guideline: 414. | - |
| Developmental toxicity/teratogenicity | Right to refer to study -- Title: Developmental toxicity study, rabbits, | Guideline: 414. | - |
| Basic toxicokinetics | Robust Study Summary -- Title: Oral dermal and inhalation pharmacokinetics and disposition of [2-14C] NMP in the rat | Author: Haskell Laboratory for Toxicology and Industrial Medicine USA | Year: 1995 | Klimisch score: 1 - Reliable without restriction. | - |
| Basic toxicokinetics | Right to refer to study -- Title: Oral dermal and inhalation pharmacokinetics and disposition of [2-14C] NMP in the rat | Author: Haskell Laboratory for Toxicology and Industrial Medicine USA | Year: 1995 | Klimisch score: 1 - Reliable without restriction. | - |
| Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: SIDS Initial Assessment Report For SIAM 24 (1-METHYL-2-PYRROLIDONE) 19-20 April 2007 Paris France | Author: OECD SIDS | Year: 2007 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Bestimmung der akuten Wirkung von N-Methylpyrrolidon-2 (NMP) gegenüber dem Wasserfloh Daphnia magna Straus. | Author: BASF AG | Year: 1982 | Klimisch score: 2 - Reliable with restrictions. | - |
| Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Bestimmung der akuten Wirkung von N-Methylpyrrolidon-2 (NMP) gegenüber dem Wasserfloh Daphnia magna Straus. | Author: BASF AG | Year: 1982 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Growth inhibition study on algae | Guideline: 201. | - |
| Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Growth inhibition study on algae | Guideline: 201. | - |
| Short-term toxicity to fish | Robust Study Summary -- Title: Short-term toxicity to fish | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions. | - |
| Short-term toxicity to fish | Right to refer to study -- Title: Short-term toxicity to fish | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions. | - |
| Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Long-term toxicity testing on Daphnia, 21-days | Guideline: 211. | - |
| Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Long-term toxicity testing on Daphnia, 21-days | Guideline: 211. | - |
| Long-term toxicity to fish | Waiver | - |
| Long-term toxicity to fish | Waiver | - |
| Long-term toxicity to fish | Waiver | - |
| Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals | Author: MITI | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Biodegradation in water: screening tests | Robust Study Summary -- Title: Ready biodegradability - Closed bottle test | Guideline: 302B. | Consortium |
| Hydrolysis | Waiver | - |
| Adsorption/desorption | Robust Study Summary -- Title: Adsorption/desorption screening study (HPLC method) | Year: 2018 | Klimisch score: 2 - Reliable with restrictions. | - |
| Adsorption/desorption | Right to refer to study -- Title: Adsorption/desorption screening study (HPLC method) | Year: 2018 | Klimisch score: 2 - Reliable with restrictions. | - |
| Adsorption/desorption | Robust Study Summary -- Title: Further studies on adsorption/desorption | Year: 2012 | Klimisch score: 2 - Reliable with restrictions. | Consortium |
| Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: N-Methylpyrrolidon - Determination of the chronic effect on the reproduction of the water flea Daphnia magna STRAUS | Year: 2001 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction. | - |
| Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: N-Methylpyrrolidon - Determination of the chronic effect on the reproduction of the water flea Daphnia magna STRAUS | Year: 2001 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction. | - |