You are here: Home> South Korea>K-REACH>CAS 9016-87-9> CAS 9016-87-9 | Data Package 1 - 10 t/a
Study name | Short Description | Data Owner |
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Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: GESTIS Substance Database Polymeric diphenylmethane diisocyanate CAS: 9016-87-9 | Author: Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA) | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Polymeric diphenylmethane 4,4'-diisocyanate (PMDI): determination of physicochemical properties | Author: Fisk PR & Langner EJ | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Polymeric diphenylmethane 4,4'-diisocyanate (PMDI): determination of physicochemical properties | Author: Fisk PR & Langner EJ | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
Phys-Chem | Boiling point | Robust Study Summary -- Title: Monographs on the Evaluation of the Carcinogenic Risk of Chemicals | Author: IARC | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
Phys-Chem | Density | Robust Study Summary -- Title: GESTIS Substance Database Polymeric diphenylmethane diisocyanate, CAS: 9016-87-9 | Author: Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA) | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor pressure of PMDI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapor pressure of PMDI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Yakabe | Year: 1997 | Adequacy: key study. | - |
Phys-Chem | Water solubility | Right to refer to study -- Title: No information | Author: Yakabe | Year: 1997 | Adequacy: key study. | - |
Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX, Buller RH, & Geil RG | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX, Buller RH, & Geil RG | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Toxicological | Skin sensitisation | Robust Study Summary -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS, and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
Toxicological | Skin sensitisation | Right to refer to study -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS, and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
Toxicological | Skin sensitisation | Robust Study Summary -- Title: Identification of chemical respiratory allergens: dose-response relationships in the mouse IgE test. | Author: Hilton J et al. | Year: 1995 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 101-68-8 | 4,4'-MDI) |
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Toxicological | Skin sensitisation | Robust Study Summary -- Title: Characterization of murine immune responses to allergenic diisocyanates. | Author: Dearman RJ, Spence LM, & Kimber I | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 101-68-8 | 4,4'-MDI) |
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Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B et al. | Year: 1998 | Guideline: EU Method B.12/B.13 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B et al. | Year: 1998 | Guideline: EU Method B.12/B.13 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N et al. | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N et al. | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with Polymeric MDI | Author: Neuhahn A | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with Polymeric MDI | Author: Neuhahn A | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |