You are here: Home> South Korea>K-REACH>CAS 9048-57-1> CAS 9048-57-1 | Data Package 100 - 1000 t/a (Read-Across)
| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Identification of chemical respiratory allergens: dose-response relationships in the mouse IgE test. | Author: Hilton J et al. | Year: 1995 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Characterization of murine immune responses to allergenic diisocyanates. | Author: Dearman RJ Spence LM & Kimber I | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 9016-87-9 | Polymeric MDI) |
- |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 9016-87-9 | Polymeric MDI) |
- |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicity Test with 4,4'-MDI/DPG, Study no. 2018/0095/01 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-040-8 | 4,4'-MDI / DPG) |
- |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute Toxicity Test with 4,4'-MDI/DPG, Study no. 2018/0095/01 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-040-8 | 4,4'-MDI | DPG) |
- |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/03 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/03 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2019/0023/02 | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2019/0023/02 | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2018/0095/03DA) | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2018/0095/03DA) | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted)Author,Study no. 2019/0023/02 | Author: CURRENTA GmbH & Co. OHG | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted)Author,Study no. 2019/0023/02 | Author: CURRENTA GmbH & Co. OHG | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: CURRENTA GmbH & Co. OHG, 2020, Daphnia sp., Acute Immobilisation Test with MDI/PPG4000, Study no. 2020/0030/01 | Author: CURRENTA GmbH & Co. OHG | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: CURRENTA GmbH & Co. OHG, 2020, Daphnia sp., Acute Immobilisation Test with MDI/PPG4000, Study no. 2020/0030/01 | Author: CURRENTA GmbH & Co. OHG | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |