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| Product Name | Short Description | Data Owner |
|---|---|---|
| Acute toxicity: oral | Robust Study Summary - Title: Nitrobenzol II. Akute orale Toxizität.; Author: Bayer AG data; Year: 1978; Guideline: 420, 423, 425; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Acute toxicity: oral | Right to refer to study - Title: Nitrobenzol II. Akute orale Toxizität.; Author: Bayer AG data; Year: 1978; Guideline: 420, 423, 425; Klimisch score: 2 (reliable with restrictions) | Bayer AG |
| Short-term toxicity to aquatic invertebrates | Robust Study Summary - Title: Toxicity, biodegradability, and accumulation of a number of CI/N-containing compounds for classification and establishing Water Quality Criteria; Author: Canton JH et al. ; Year: 1985; Guideline: 202; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Short-term toxicity to aquatic invertebrates | Right to refer to study - Title: Toxicity, biodegradability, and accumulation of a number of CI/N-containing compounds for classification and establishing Water Quality Criteria; Author: Canton JH et al. ; Year: 1985; Guideline: 202; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Boiling point | Robust Study Summary - Title: nItrobenzene; Author: Lide, D.R. (ed.); Year: 1996; Guideline: 103; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Boiling point | Right to refer to study - Title: nItrobenzene; Author: Lide, D.R. (ed.); Year: 1996; Guideline: 103; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Short-term toxicity to fish | Robust Study Summary - Title: Testung wassergefährdender Stoffe als Grundlage für Wasserqualitätsstandards; Author: Roederer G.; Year: 1990; Guideline: 203; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Short-term toxicity to fish | Right to refer to study - Title: Testung wassergefährdender Stoffe als Grundlage für Wasserqualitätsstandards; Author: Roederer G.; Year: 1990; Guideline: 203; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Melting point/freezing point | Robust Study Summary - Title: Bestimmung des Erstarrungspunktes der Probe: Nitrobenzol v. 28.09.86; Author: BASF AG ; Year: 1986; Guideline: 102; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Melting point/freezing point | Right to refer to study - Title: Bestimmung des Erstarrungspunktes der Probe: Nitrobenzol v. 28.09.86; Author: BASF AG ; Year: 1986; Guideline: 102; Klimisch score: 2 (reliable with restrictions) | BASF AG |
| Partition coefficient | Robust Study Summary - Title: Bestimmung des Verteilungskoeffizienten Pow von Nitrobenzol in n-Octanol/Wasser; Author: BASF AG; Year: 1987; Guideline: 107/117; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Partition coefficient | Right to refer to study - Title: Bestimmung des Verteilungskoeffizienten Pow von Nitrobenzol in n-Octanol/Wasser; Author: BASF AG; Year: 1987; Guideline: 107/117; Klimisch score: 2 (reliable with restrictions) | BASF SE |
| Biodegradation in water: screening tests | Robust Study Summary - Title: Biodegradability in the Respirometric Test (Oxi Top Control Testsystem); Author: BASF AG; Year: 2000; Guideline: 301C; Klimisch score: 1 (reliable without restriction) | Consortium |
| Biodegradation in water: screening tests | Right to refer to study - Title: Biodegradability in the Respirometric Test (Oxi Top Control Testsystem); Author: BASF AG; Year: 2000; Guideline: 301C; Klimisch score: 1 (reliable without restriction) | BASF SE |
| Density | Robust Study Summary - Title: nitrobenzene; Author: European Chemicals Bureau; Year: 2007; Guideline: 109; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Density | Right to refer to study - Title: nitrobenzene; Author: European Chemicals Bureau; Year: 2007; Guideline: 109; Klimisch score: 2 (reliable with restrictions) | Consortium |
| in vitro gene mutation study in bacteria (Ames) | Robust Study Summary - Title: Use of Primary Cultures of Human Hepatocytes in Toxicology Studies; Author: Butterworth, B. E. et al. ; Year: 1989; Guideline: 471; Klimisch score: 2 (reliable with restrictions) | Consortium |
| in vitro gene mutation study in bacteria (Ames) | Right to refer to study - Title: Use of Primary Cultures of Human Hepatocytes in Toxicology Studies; Author: Butterworth, B. E. et al. ; Year: 1989; Guideline: 471; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Skin sensitisation | Robust Study Summary - Title: Nitrobenzene: Local lymph node assay in mice (LLNA/IMDS); Author: Vohr HW; Year: 2008; Guideline: 406, 429; Klimisch score: 1 (reliable without restriction) | Consortium |
| Skin sensitisation | Right to refer to study - Title: Nitrobenzene: Local lymph node assay in mice (LLNA/IMDS); Author: Vohr HW; Year: 2008; Guideline: 406, 429; Klimisch score: 1 (reliable without restriction) | "ISOPA, Brussels, Belgium" |
| Skin irritation / corrosion | Robust Study Summary - Title: Nitrobenzol II. Untersuchung zur Haut- und Schleimheutvertträglichkeit.; Author: Thyssen, J.; Year: 1979; Guideline: 404; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Skin irritation / corrosion | Right to refer to study - Title: Nitrobenzol II. Untersuchung zur Haut- und Schleimheutvertträglichkeit.; Author: Thyssen, J.; Year: 1979; Guideline: 404; Klimisch score: 2 (reliable with restrictions) | Bayer AG |
| Vapour pressure | Robust Study Summary - Title: Nitrobenzene; Author: Beilstein; Year: 2007; Guideline: 104; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Vapour pressure | Right to refer to study - Title: Nitrobenzene; Author: Beilstein; Year: 2007; Guideline: 104; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Water solubility | Robust Study Summary - Title: Nitrobenzene; Author: Bayer AG; Year: 1998; Guideline: 105; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Water solubility | Right to refer to study - Title: Nitrobenzene; Author: Bayer AG; Year: 1998; Guideline: 105; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Acute toxicity: dermal | Robust Study Summary - Title: Toxicological and skin corrosion testing of selected hazardous materials.; Author: Harton, E. E. and Rawl, R. R. ; Year: 1976; Guideline: 402; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Acute toxicity: dermal | Right to refer to study - Title: Toxicological and skin corrosion testing of selected hazardous materials.; Author: Harton, E. E. and Rawl, R. R. ; Year: 1976; Guideline: 402; Klimisch score: 2 (reliable with restrictions) | "Office of Hazardous Materials Operations, U. S. Department of Transportation" |
| Acute toxicity: inhalation | Robust Study Summary - Title: Bericht über die Prüfung der akuten Inhalationsgefahr von Nitrobenzol an der Ratte; Author: Freisberg; Year: 1977; Guideline: 403; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Acute toxicity: inhalation | Right to refer to study - Title: Bericht über die Prüfung der akuten Inhalationsgefahr von Nitrobenzol an der Ratte; Author: Freisberg; Year: 1977; Guideline: 403; Klimisch score: 2 (reliable with restrictions) | BASF AG |
| Flammability | Robust Study Summary - Title: NIzrobenzene; Author: BAM; Year: 1997; Guideline: A 10; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Flammability | Right to refer to study - Title: NIzrobenzene; Author: BAM; Year: 1997; Guideline: A 10; Klimisch score: 2 (reliable with restrictions) | Consortium |
| oxidising properties test | Robust Study Summary - Title: Nitrobenzene; Author: European Chemicals Bureau; Year: 2007; Guideline: A 17; Klimisch score: 1 (reliable without restriction) | Consortium |
| oxidising properties test | Right to refer to study - Title: Nitrobenzene; Author: European Chemicals Bureau; Year: 2007; Guideline: A 17; Klimisch score: 1 (reliable without restriction) | Consortium |
| Eye irritation | Robust Study Summary - Title: Nitrobenzol II. Untersuchung zur Haut- und Schleimheutvertträglichkeit.; Author: Thyssen, J.; Year: 1979; Guideline: 405; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Eye irritation | Right to refer to study - Title: Nitrobenzol II. Untersuchung zur Haut- und Schleimheutvertträglichkeit.; Author: Thyssen, J.; Year: 1979; Guideline: 405; Klimisch score: 2 (reliable with restrictions) | Bayer AG |
| in vitro gene mutation study in mammalian cells (MLA) | Robust Study Summary - Title: Salmonella mutagenicity test results for 250 chemicals.; Author: Haworth, S. et al. ; Year: 1983; Guideline: 476, 474, 475; Klimisch score: 2 (reliable with restrictions) | Consortium |
| in vitro gene mutation study in mammalian cells (MLA) | Right to refer to study - Title: Salmonella mutagenicity test results for 250 chemicals.; Author: Haworth, S. et al. ; Year: 1983; Guideline: 476, 474, 475; Klimisch score: 2 (reliable with restrictions) | Consortium |
| in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary - Title: Cytogenetic study in vivo of Nitrobenzene in mice - Micronucleus test.; Author: Adler, I.; Year: 1996; Guideline: 473, 485; Klimisch score: 1 (reliable without restriction) | Consortium |
| in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study - Title: Cytogenetic study in vivo of Nitrobenzene in mice - Micronucleus test.; Author: Adler, I.; Year: 1996; Guideline: 473, 485; Klimisch score: 1 (reliable without restriction) | "BASF AG, Bayer AG and Zeneca" |
| screening test for reproductive/developmental toxicity (OECD 421) - inhalation | Robust Study Summary - Title: Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.; Author: Dodd, D.E. et al.; Year: 1987; Guideline: 421, 422; Klimisch score: 2 (reliable with restrictions) | Consortium |
| screening test for reproductive/developmental toxicity (OECD 421) - inhalation | Right to refer to study - Title: Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation.; Author: Dodd, D.E. et al.; Year: 1987; Guideline: 421, 422; Klimisch score: 2 (reliable with restrictions) | Consortium |
| short term repeated dose toxicity study (28 days) | Robust Study Summary - Title: A 28-day repeated dose toxicity study of nitrobenzene in F344 rats.; Author: Shimo, T. et al.; Year: 1994; Guideline: 407, 410, 412; Klimisch score: 2 (reliable with restrictions) | Consortium |
| short term repeated dose toxicity study (28 days) | Right to refer to study - Title: A 28-day repeated dose toxicity study of nitrobenzene in F344 rats.; Author: Shimo, T. et al.; Year: 1994; Guideline: 407, 410, 412; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to soil macroorganisms except arthropods | Robust Study Summary - Title: Comparative toxicity of ten organic chemicals to four earthworm species; Author: Neuhauser et al.; Year: 1986; Guideline: 207; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to soil macroorganisms except arthropods | Right to refer to study - Title: Comparative toxicity of ten organic chemicals to four earthworm species; Author: Neuhauser et al.; Year: 1986; Guideline: 207; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to aquatic algae and cyanobacteria | Robust Study Summary - Title: Aquatic toxicity Of aromatic nitro compounds and anilines to several freshwater species; Author: Maas-Diepeveen J.L. & van Leeuwen C.J.; Year: 1986; Guideline: 221; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to aquatic algae and cyanobacteria | Right to refer to study - Title: Aquatic toxicity Of aromatic nitro compounds and anilines to several freshwater species; Author: Maas-Diepeveen J.L. & van Leeuwen C.J.; Year: 1986; Guideline: 221; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Genetic toxicity in vivo | Robust Study Summary - Title: Cytogenetic study in vivo of Nitrobenzene in mice - Micronucleus test.; Author: Adler, I.; Year: 1996; Guideline: 486; Klimisch score: 1 (reliable without restriction) | Consortium |
| Genetic toxicity in vivo | Right to refer to study - Title: Cytogenetic study in vivo of Nitrobenzene in mice - Micronucleus test.; Author: Adler, I.; Year: 1996; Guideline: 486; Klimisch score: 1 (reliable without restriction) | "BASF AG, Bayer AG and Zeneca" |
| Long-term toxicity to fish | Robust Study Summary - Title: The Aquatic Toxicity of Organic Compounds t o Embryo-Larval Stages of Fish and Amphibians; Author: Black et al. ; Year: 1982; Guideline: 210; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Long-term toxicity to fish | Right to refer to study - Title: The Aquatic Toxicity of Organic Compounds t o Embryo-Larval Stages of Fish and Amphibians; Author: Black et al. ; Year: 1982; Guideline: 210; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Long-term toxicity to aquatic invertebrates | Robust Study Summary - Title: Schadstoffwirkungen von Umwekchemikalkn im Daphnien-Reproduktions-Test als Grundlage für die Bewertung der Umwekgefährlichkeit in aquatischen Systemen; Author: Kuehn R. et al; Year: 1988; Guideline: 211; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Long-term toxicity to aquatic invertebrates | Right to refer to study - Title: Schadstoffwirkungen von Umwekchemikalkn im Daphnien-Reproduktions-Test als Grundlage für die Bewertung der Umwekgefährlichkeit in aquatischen Systemen; Author: Kuehn R. et al; Year: 1988; Guideline: 211; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to aquatic algae and cyanobacteria | Robust Study Summary - Title: Aquatic toxicity Of aromatic nitro compounds and anilines to several freshwater species; Author: Maas-Diepeveen J.L. & van Leeuwen C.J.; Year: 1986; Guideline: 201; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to aquatic algae and cyanobacteria | Right to refer to study - Title: Aquatic toxicity Of aromatic nitro compounds and anilines to several freshwater species; Author: Maas-Diepeveen J.L. & van Leeuwen C.J.; Year: 1986; Guideline: 201; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to microorganisms | Robust Study Summary - Title: A database of chemical toxicity to environmental bacteria and its use in interspecies comparisons and correlations; Author: Blum D.J.W. and Speece R.E.; Year: 1991; Guideline: 209; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Toxicity to microorganisms | Right to refer to study - Title: A database of chemical toxicity to environmental bacteria and its use in interspecies comparisons and correlations; Author: Blum D.J.W. and Speece R.E.; Year: 1991; Guideline: 209; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Viscosity | Robust Study Summary - Title: Nitrobenzene; Author: Weast, R.C. (ed.) ; Year: 1987; Guideline: 114; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Viscosity | Right to refer to study - Title: Nitrobenzene; Author: Weast, R.C. (ed.) ; Year: 1987; Guideline: 114; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Adsorption / desorption | Robust Study Summary - Title: European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3; Author: European Chemicals Bureau; Year: 2007; Guideline: ; Klimisch score: 1 (reliable without restriction) | Consortium |
| Adsorption / desorption | Right to refer to study - Title: European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3; Author: European Chemicals Bureau; Year: 2007; Guideline: ; Klimisch score: 1 (reliable without restriction) | Consortium |
| Phototransformation in air | Robust Study Summary - Title: Atmospheric chemistry of aniline, N,N-dimethylaniline, pyridine, 1,3,5-triazine and nitrobenzene; Author: Atkinson R. et al.; Year: 1987; Guideline: 312; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Phototransformation in air | Right to refer to study - Title: Atmospheric chemistry of aniline, N,N-dimethylaniline, pyridine, 1,3,5-triazine and nitrobenzene; Author: Atkinson R. et al.; Year: 1987; Guideline: 312; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Adsorption / desorption | Robust Study Summary - Title: European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3; Author: European Chemicals Bureau; Year: 2007; Guideline: 106; Klimisch score: 0 | Consortium |
| Adsorption / desorption | Right to refer to study - Title: European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3; Author: European Chemicals Bureau; Year: 2007; Guideline: 106; Klimisch score: 0 | Consortium |
| Bioaccumulation: aquatic / sediment | Robust Study Summary - Title: Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan; Author: MITI; Year: 1992; Guideline: 305; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Bioaccumulation: aquatic / sediment | Right to refer to study - Title: Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan; Author: MITI; Year: 1992; Guideline: 305; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Carcinogenicity | Robust Study Summary - Title: A chronic inhalation toxicity study of nitrobenzene in B6C3F1 mice, Fischer 344 rats and Sprague-Dawley (CD) rats. Volume I and II.; Author: Popp, J.A.; Year: 1993; Guideline: 451; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Carcinogenicity | Right to refer to study - Title: A chronic inhalation toxicity study of nitrobenzene in B6C3F1 mice, Fischer 344 rats and Sprague-Dawley (CD) rats. Volume I and II.; Author: Popp, J.A.; Year: 1993; Guideline: 451; Klimisch score: 2 (reliable with restrictions) | Chemical Industry Institute of Toxicology |
| Carcinogenicity | Robust Study Summary - Title: A chronic inhalation toxicity study of nitrobenzene in B6C3F1 mice, Fischer 344 rats and Sprague-Dawley (CD) rats. Volume I and II.; Author: Popp, J.A.; Year: 1993; Guideline: 453; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Carcinogenicity | Right to refer to study - Title: A chronic inhalation toxicity study of nitrobenzene in B6C3F1 mice, Fischer 344 rats and Sprague-Dawley (CD) rats. Volume I and II.; Author: Popp, J.A.; Year: 1993; Guideline: 453; Klimisch score: 2 (reliable with restrictions) | Chemical Industry Institute of Toxicology |
| sub-chronic toxicity study (90 days; oral route) (rat) | Robust Study Summary - Title: Immunotoxicity of nitrobenzene in female B6C3F1 mice; Author: Burns et al.; Year: 1994; Guideline: 408, 409, 411, 413; Klimisch score: 2 (reliable with restrictions) | Consortium |
| sub-chronic toxicity study (90 days; oral route) (rat) | Right to refer to study - Title: Immunotoxicity of nitrobenzene in female B6C3F1 mice; Author: Burns et al.; Year: 1994; Guideline: 408, 409, 411, 413; Klimisch score: 2 (reliable with restrictions) | Consortium |
| two-generation reproductive toxicity study (one species; oral route) | Robust Study Summary - Title: Confirmation study, using nitrobenzene, of the combined repat dose and reproductive/developmental toxicity test protocol proposed by the Organization for Economic Cooperation and Development (OECD).; Author: Mitsumori, K. et al.; Year: 1994; Guideline: 416; Klimisch score: 2 (reliable with restrictions) | Consortium |
| two-generation reproductive toxicity study (one species; oral route) | Right to refer to study - Title: Confirmation study, using nitrobenzene, of the combined repat dose and reproductive/developmental toxicity test protocol proposed by the Organization for Economic Cooperation and Development (OECD).; Author: Mitsumori, K. et al.; Year: 1994; Guideline: 416; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Developmental toxicity / teratogenicity | Robust Study Summary - Title: An inhalation teratology study in rabbits with nitrobenzene. Final Report; Author: Bio/dynamics Inc.; Year: 1984; Guideline: 414; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Developmental toxicity / teratogenicity | Right to refer to study - Title: An inhalation teratology study in rabbits with nitrobenzene. Final Report; Author: Bio/dynamics Inc.; Year: 1984; Guideline: 414; Klimisch score: 2 (reliable with restrictions) | "Nitrobenzene Association Toxicology Task Group, Wilmington, Delaware, USA" |
| Developmental toxicity / teratogenicity | Robust Study Summary - Title: Developmental toxicity of inhaled nitrobenzene in CD rats.; Author: Tyl, R.W. et al.; Year: 1987; Guideline: 414; Klimisch score: 2 (reliable with restrictions) | Consortium |
| Developmental toxicity / teratogenicity | Right to refer to study - Title: Developmental toxicity of inhaled nitrobenzene in CD rats.; Author: Tyl, R.W. et al.; Year: 1987; Guideline: 414; Klimisch score: 2 (reliable with restrictions) | Consortium |