You are here: Home> South Korea>K-REACH>CAS 994-05-8> CAS 994-05-8 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Additional information to the Finnish Environmental Institute regarding TAME risk assessment | Author: Fortum - Perander J. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Additional information to the Finnish Environmental Institute regarding TAME risk assessment | Author: Fortum (2001) Perander J. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Odor and Taste Threshold studies Performed with Tertiary-Amyl Methyl Ether (TAME). | Author: Vetrano K | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: TAME: determination of melting point/melting range | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: TAME: determination of melting point/melting range | Author: Harlan Laboratories Ltd. | Year: 2009 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Hellenic Petroleum S.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: No information | Author: Hellenic Petroleum S.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D et al. (eds.) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline. | Author: Huttunen H | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Identification of the environmental hazards of gasoline oxygenate tert-amyl methyl ether (TAME). | Author: Huttunen H Wyness LE and Kalliokoski P | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide DR (ed.) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: TAME: determination of vapour pressure. | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: TAME: determination of vapour pressure. | Author: Harlan Laboratories Ltd. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor pressures of methyl tert-butyl ether ethyl tert-butyl ether isopropyl tert-butyl ether tert-amyl methyl ether and tert-amyl ethyl ether | Author: Krahenbuhl MA and Gmehling J | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Identification of the environmental hazards of gasoline oxygenate tert-amyl methyl ether (TAME) | Author: Huttunen H Wyness LE Kalliokoski P | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline. | Author: Huttunen H | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline. | Author: Huttunen H | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Identification of the environmental hazards of gasoline oxygenate tert-amyl methyl ether (TAME). | Author: Huttunen H Wyness LE and Kalliokoski P | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of the water-solubility of gasolines containing ethers | Author: Oil Product Research | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of the water-solubility of gasolines containing ethers | Author: Oil Product Research | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Identification of the environmental hazards of gasoline oxygenate tert-amyl methyl ether (TAME) | Author: Huttunen H Wyness LE Kalliokoski P | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline | Author: Huttunen H | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Mutual solubilities : water-ketones water-ethers and water-gasoline-alcohols. | Author: Stephenson RM | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Study of fuel oxygenates solubility in aqueous media as a function of temperature and tert-butyl alcohol concentration | Author: Gonzalez-Olmos R Iglesias M | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: TAME: Determination of viscosity and surface tension | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: TAME: Determination of viscosity and surface tension | Author: SafePharm Laboratories Ltd. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Empfohlene Sicherheitstechnische Kenngroessen | Author: PTB-Laboratorium 3.43 | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Sicherheitstechnische Kennzahlen brennbarer Gase und Daempfe (mit 6. Nachtrag) | Author: Nabert K Schoen G | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline | Author: Huttunen H | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Risk assessment of complex petroleum substances: hazard identification of NExTAME and re-formulated gasoline | Author: Huttunen H | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Identification of the environmental hazards of gasoline oxygenate tert-amyl methyl ether (TAME) | Author: Huttunen H Wyness LE Kalliokoski P | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Tertiary amyl methyl ether (TAME):assessment of ready biodegradability by measurement of oxygen uptake | Author: Hazleton Europe | Year: 1995 | Guideline: 301 D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Tertiary amyl methyl ether (TAME):assessment of ready biodegradability by measurement of oxygen uptake | Author: Hazleton Europe | Year: 1995 | Guideline: 301 D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Risk assessment of complex petroleum substances : hazard identification of NExTAME and re-formulated gasoline | Author: Huttunen H | Year: 1996 | Guideline: 301 D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Risk assessment of complex petroleum substances : hazard identification of NExTAME and re-formulated gasoline | Author: Huttunen H | Year: 1996 | Guideline: 301 D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ready Biodegradability 'Determination of BOD - Closed Bottle Test' Test substance: TAME (tert-amyl methyl ether) In comparison with: MTBE (Methyl tert-butyl ether) a ETBE (Ethyl tert-butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Guideline: 301 D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ready Biodegradability 'Determination of BOD - Closed Bottle Test' Test substance: TAME (tert-amyl methyl ether) In comparison with: MTBE (Methyl tert-butyl ether) a ETBE (Ethyl tert-butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Guideline: 301 D | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Aerobic degradation of ethyl-tert-butyl ether by a microbial consortium: selection and evaluation of biodegradation ability | Author: Kharoune M Kharoune L Lebault J-M and Pauss A | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Solubility and degradability of the gasoline additive MTBE methyl tert butyl ether and gasoline compounds in water. | Author: Jensen HM and Arvin E | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of ethyl t-butyl ether (ETBE) methyl t-butyl ether (MTBE) and t-amyl methyl ether (TAME) by Gordonia terrae. | Author: Hernandez-Perez G Fayolle F and Vandecastelee J-P | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: MTBE biodegradation in the presence of other gasoline components | Author: Eweis JB Watanabe NC Schroeder ED Chang DPY and Scow KM | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of the gasoline oxygenates MTBE ETBE TAME TBA and TAA by aerobic mixed cultures | Author: Cowan R Park K | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Aerobic biodegradation of an oxygenates mixture: ETBE MTBE and TAME in an upflow fixed-bed reactor | Author: Kharoune M Pauss A and Lebeault JM | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of the gasoline oxygenates methyl tert-butyl ether ethyl tert-butyl ether and tert-amyl methyl ether by propane oxidising bacteria | Author: Steffan RJ McClay K Vainberg S Condee CW and Zhang D | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Tert amyl methyl ether (TAME) - acute toxicity to rainbow trout (Oncorhynchus mykiss) under flow-through conditions | Author: Springborn Laboratories Inc. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicity of Methyl-Tertiary Butyl Ether (MTBE) to Aquatic Organisms | Author: BenKinney MT Barbieri JF Gross JS & Naro PA | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: TAME : Acute toxicity to Oncorhynchus mykiss | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: TAME : Acute toxicity to Oncorhynchus mykiss | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute lethal toxicity with Poecilia reticulata Test substance: TAME (tert-amyl butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute lethal toxicity with Poecilia reticulata Test substance: TAME (tert-amyl butyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Cranofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME. | Author: Boventre JA White LA Cooper KR | Year: 2012 | Guideline: 212 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Cranofacial abnormalities and altered wnt and mmp mRNA expression in zebrafish embryos exposed to gasoline oxygenates ETBE and TAME. | Author: Bonventre JA White LA Cooper KR | Year: 2012 | Guideline: 212 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Tert amyl methyl ether (TAME) - acute toxicity to Mysid shrimp (Mysidopsis bahia) under static renewal conditions | Author: Springborn Laboratories Inc. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Tert amyl methyl ether (TAME) - acute toxicity to Daphnids (Daphnia magna) under flow-through conditions | Author: Springborn Laboratories Inc. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | - | |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute immobilization test with Daphnia magna Test substance: TAME (tert-amyl methyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: TAME : Acute toxicity to Daphnia magna | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: TAME : Acute toxicity to Daphnia magna | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: 2-Methoxy-methylbutane (TAME): Algal Inhibition Test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: 2-Methoxy-methylbutane (TAME): Algal Inhibition Test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: TAME : Inhibition of growth to the alga Selenastrum capricornutum | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: TAME : Inhibition of growth to the alga Selenastrum capricornutum | Author: Corning Hazleton | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: 2-Methoxy-methylbutane (TAME): Algal Inhibition Test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: 2-Methoxy-methylbutane (TAME): Algal Inhibition Test | Author: SafePharm Laboratories | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga growth inhibition test Test substance: TAME (tert-amyl methyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga growth inhibition test Test substance: TAME (tert-amyl methyl ether) | Author: Slovnaft VÚRUP a.s. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Biotransformation of MTBE ETBE and TAME after inhalation or ingestion in rats and humans | Author: Dekant W Bernauer U Rosner E Amberg A | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity test in the rat final report test material MRD-89-374 | Author: Exxon Biomedical Sciences Inc. | Year: 1989 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity test in the rat final report test material MRD-89-374 | Author: Exxon Biomedical Sciences Inc. | Year: 1989 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute inhalation toxicity study of tert-amyl methyl ether (TAME) in rats final report | Author: IIT Research Institute | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Acute inhalation toxicity study of tert-amyl methyl ether (TAME) in rats final report | Author: IIT Research Institute | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute dermal toxicity of tert-Amyl Methyl ether (TAME) in rabbits final report | Author: IIT Research Institute | Year: 1991 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute dermal toxicity of tert-Amyl Methyl ether (TAME) in rabbits final report | Author: IIT Research Institute | Year: 1991 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: TAME (2-methyl-2-methoxybutan) - study for skin and eye irritation / corrosion in rabbits. | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: TAME (2-methyl-2-methoxybutan) - study for skin and eye irritation / corrosion in rabbits. | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: TAME (2-methyl-2-methoxybutan) - study for skin and eye irritation / corrosion in rabbits. | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: TAME (2-methyl-2-methoxybutan) - study for skin and eye irritation / corrosion in rabbits. | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Closed patch repeated insult dermal sensitisation study of tertiary amyl methyl ether (TAME) in guinea pigs (Buehler method) | Author: Pharmaco LSR | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Genotoxicity and twenty-eight day subchronic toxicity studies on tertiary amylmethyl ether | Author: Daughtrey WC and Bird MG | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 13 week inhalation toxicity/neurotoxicity study of tert-amyl methyl ether(TAME) in the rat and mouse via whole-body exposures with a 4-week recovery period. | Author: Huntingdon Life Sciences | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Four-week inhalation toxicity study of tert-Amyl Methyl Ether (TAME) in rats | Author: IIT Research Institute (IITRI) | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Four-week inhalation toxicity study of tert-Amyl Methyl Ether (TAME) in rats | Author: IIT Research Institute (IITRI) | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Health effects of inhaled tertiary amyl methyl ether and ethyl tertiary butyl ether | Author: White RD Daughtrey WC and Wells MS | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: TAME - salmonella/microsome test | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: TAME - salmonella/microsome test | Author: Bayer AG | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Microbial mutagenesis in Salmonella mammalian microsome plate incorporation assay | Author: Exxon Biomedical Sciences Inc | Year: 1989 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Microbial mutagenesis in Salmonella mammalian microsome plate incorporation assay | Author: Exxon Biomedical Sciences Inc | Year: 1989 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Genotoxicity and twenty-eight day subchronic toxicity studies on tertiary amylmethyl ether | Author: Daughtrey WC and Bird MG | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosomal aberrations in chinese hamster ovary (CHO) cells | Author: Microbiological Associates Inc. | Year: 1996 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: CHO/HGPRT mutation assay amended final report | Author: Microbiological Associates Inc. | Year: 1996 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: In vivo mammalian bone marrow micronucleus assay | Author: Exxon Biomedical Sciences Inc | Year: 1989 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Genotoxicity and twenty-eight day subchronic toxicity studies on tertiary amylmethyl ether | Author: Daughtrey WC and Bird MG | Year: 1995 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Two-generation reproductive toxicity evaluation of inhaled tertiary amyl methyl ether (TAME) vapor in CD(Sprague-Dawley) rats. | Author: Chemical Industry Institute of Toxicology(CIIT) | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Two-generation Reproductive Toxicity Study of Inhaled tertiary Amyl Methyl Ether (TAME) Vapor in CD Rats | Author: Tyl RW Myers CB Marr MC Fail PA Seely JC Elswick B James A and Welsch F | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |