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CAS 999-97-3 | Data Package 10 - 100 t/a

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Includes:

Study name Short Description Data Owner
Acute toxicity: inhalation Robust Study Summary -- Title: An Acute Whole Body Inhalation Toxicity Study of Hexamethyldisilazane in Sprague-Dawley Rats; | Author: Dow Corning Corporation | Year: 2007 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Acute toxicity: inhalation Right to refer to study -- Title: An Acute Whole Body Inhalation Toxicity Study of Hexamethyldisilazane in Sprague-Dawley Rats; | Author: Dow Corning Corporation | Year: 2007 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: An acute eye irritation study of Dow Corning z-6079 in albino rats | Author: Dow Corning Corporation | Year: 1993 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: An acute eye irritation study of Dow Corning z-6079 in albino rats | Author: Dow Corning Corporation | Year: 1993 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Final Report induction of chromosome aberrations in cultured human peripheral blood lymphocytes, with cover letter dated 1/19/1998 (sanitized) | Author: Covance Laboratories Ltd | Year: 1997 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: Final Report induction of chromosome aberrations in cultured human peripheral blood lymphocytes, with cover letter dated 1/19/1998 (sanitized) | Author: Covance Laboratories Ltd | Year: 1997 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Hydrolysis Robust Study Summary -- Title: Hydrolysis of Hexamethyldisilazane (HMDZ) | Author: Miller J A | Year: 2006 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Hydrolysis Right to refer to study -- Title: Hydrolysis of Hexamethyldisilazane (HMDZ) | Author: Miller J A | Year: 2006 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: Determination of the Freezing Point / Freezing Range | Author: Franke J | Year: 2008 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: Determination of the Freezing Point / Freezing Range | Author: Franke J | Year: 2008 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Determination of the biodegradability of DYNASYLAN HMDS in a closed bottle test (in accordance with EEC 92/69 C4-E); | Author: Schoberl; Huls AG | Year: 1994 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Determination of the biodegradability of DYNASYLAN HMDS in a closed bottle test (in accordance with EEC 92/69 C4-E); | Author: Schoberl; Huls AG | Year: 1994 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: An Acute Skin Irritation/Corrosion Study in Albino Rabbits | Author: Dow Corning Corporation | Year: 1993 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Right to refer to study -- Title: An Acute Skin Irritation/Corrosion Study in Albino Rabbits | Author: Dow Corning Corporation | Year: 1993 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Hexamethyldisilazane in Sprague-Dawley Rats via Inhalation Exposure (Draft Report) | Author: Dow Corning Corporation | Year: 2008 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Hexamethyldisilazane in Sprague-Dawley Rats via Inhalation Exposure (Draft Report) | Author: Dow Corning Corporation | Year: 2008 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: Critical Point and Vapor Pressure Measurements on Hexamethyldisilazane by Means of a Flow Method with Ultralow Residence Times; The Properties of Gases and Liquids 51st Edition; review article or handbook; | Author: VonNiederhausern D M; Design Institute for Physical Property Research; Wiltec Research Company; Poling B E et al. | Year: 2003; 2003; 2001 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Right to refer to study -- Title: Critical Point and Vapor Pressure Measurements on Hexamethyldisilazane by Means of a Flow Method with Ultralow Residence Times; The Properties of Gases and Liquids 51st Edition; review article or handbook; | Author: VonNiederhausern D M; Design Institute for Physical Property Research; Wiltec Research Company; Poling B E et al. | Year: 2003; 2003; 2001 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Robust Study Summary -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates - I | Author: Dow Corning Corporation | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flash point Right to refer to study -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates - I | Author: Dow Corning Corporation | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Robust Study Summary -- Title: The Merck Index, An Encyclopedia Of Chemicals, Drugs, And Biologicals | Author: O'Neil M J (ed) | Year: 2006 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Mouse Lymphoma assay Microbiological Associates; study report; Study No. ML-NCI #259;Chemical Carcinogenesis Research Information System ;other: | Author: Microbiological Associates Inc.; CCRIS | Year: 1991; 1991 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Final report; reverse mutation in five hisitidine-requiring strains of Salmonella typhimurium | Author: Covance; Degussa-Huls AG | Year: 1997 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Final report; reverse mutation in five hisitidine-requiring strains of Salmonella typhimurium | Author: Covance; Degussa-Huls AG | Year: 1997 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Organofunctional Silane A-166: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Right to refer to study -- Title: Organofunctional Silane A-166: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: The effect of Trimethylsilanol on the incidence of Chromosome Breaks and Aberrations in Rat Bone Marrow Cells | Author: Bioassay Systems Corporation | Year: 1982 | Guideline: 475 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Genetic toxicity in vivo Robust Study Summary -- Title: Evaluation of Trimethylsilanol in the Rodent Dominant Lethal Assay | Author: Dow Corning Corporation | Year: 1983 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Genetic toxicity in vivo Right to refer to study -- Title: Evaluation of Trimethylsilanol in the Rodent Dominant Lethal Assay | Author: Dow Corning Corporation | Year: 1983 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physic | Author: Lide D R | Year: 2007 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Determination of the acute effects of DYNASYLAN HMDS On the swimming behavior of Daphnia magna (in accordance with EG 92/69/EEC); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Determination of the acute effects of DYNASYLAN HMDS On the swimming behavior of Daphnia magna (in accordance with EG 92/69/EEC); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Robust Study Summary -- Title: Determination of the acute effects of DYNASIL 40 On fish (in accordance with EEC 92/69 C 1); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to fish Right to refer to study -- Title: Determination of the acute effects of DYNASIL 40 On fish (in accordance with EEC 92/69 C 1); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Determination of the acute effects of DYNASYLAN HMDS On the growth of Scenedesmus subspicatus 86.81.SAG (algae growth test per Guideline 92/69/EEC); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Determination of the acute effects of DYNASYLAN HMDS On the growth of Scenedesmus subspicatus 86.81.SAG (algae growth test per Guideline 92/69/EEC); | Author: Hüls Aktiengesellschaft | Year: 1994 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -