You are here: Home> Turkey>TR-REACH>CAS 105-60-2> CAS 105-60-2 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: NIOSH Pocket Guide to Chemical Hazard | Author: NIOSH | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: epsilon-Caprolactam | Author: BGIA GESTIS | Year: 2019 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide D.R. | Year: 1998 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 6-caprolactam | Author: Beilstein | Year: 2006 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Lide D.R. | Year: 1998 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physikalisch-chemische Konstanten | Author: BASF AG | Year: 1988 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Physikalisch-chemische Konstanten | Author: BASF AG | Year: 1988 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physico-chemical properties of "Caprolactam Tabletten" for REACH | Author: BASF SE | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physico-chemical properties of "Caprolactam Tabletten" for REACH | Author: BASF SE | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physikalische Chemie Dampfdruck von Epsilon- Caprolactam | Author: BASF AG | Year: 1992 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physikalische Chemie Dampfdruck von Epsilon- Caprolactam | Author: BASF AG | Year: 1992 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Caprolactam | Author: Jones A.H. | Year: 1960 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physikalisch-chemische Konstanten | Author: BASF AG | Year: 1988 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physikalisch-chemische Konstanten | Author: BASF AG | Year: 1988 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | HLC | Robust Study Summary -- Title: SRC HENRY v3.10 | Author: BASF SE | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | HLC | Right to refer to study -- Title: SRC HENRY v3.10 | Author: BASF SE | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: epsilon - Caprolactam | Author: BGIA GESTIS | Year: 2019 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Caprolactam | Author: Husigen Brade | Year: 1957 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: no title | Author: Loewengart G. | Year: 1984 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Caprolactam | Author: BASF AG | Year: 2007 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Bestimmung des Verteilungscoeffizienten log POW von Caprolactam in 1-Octanol/Wasser bei Raumtemperatur | Author: BASF AG | Year: 1988 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Bestimmung des Verteilungscoeffizienten log POW von Caprolactam in 1-Octanol/Wasser bei Raumtemperatur | Author: BASF AG | Year: 1988 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Physico-chemical properties of "Caprolactam Tabletten" for REACH | Author: BASF SE | Year: 2009 | Guideline: 110 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Physico-chemical properties of "Caprolactam Tabletten" for REACH | Author: BASF SE | Year: 2009 | Guideline: 110 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Abbrandgeschwindigkeit von Caprolactam | Author: BASF SE | Year: 2009 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Abbrandgeschwindigkeit von Caprolactam | Author: BASF SE | Year: 2009 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Dermal Sensitization studies in Guinea pigs with Caprolactam. | Author: Springborn Laboratories Inc. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosomal analyses of human lymphocytes exposed in vitro to caprolactam. | Author: Kristiansen E. & Scott D. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture. | Author: Myhr B. et al. | Year: 1985 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome Aberration and Sister Chromatid Exchange Tests in Chinese Hamster Ovary Cells In Vitro III: Results With 27 Chemicals | Author: Gulati D.K. et al. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Tests for the induction of chromosomal aberrations and sister chromatid exchanges in cultured Chinese hamster ovary (CHO) cells. | Author: Gulati D.K. et al. | Year: 1985 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Tests for mutagenic activity at the HGPRT locus in Chinese hamster V79 cells in culture. | Author: Fox M. & Delow G.F. | Year: 1985 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Alkaline sucrose sedimentation sister-chromatid exchange and micronucleus assays in CHO cells | Author: Douglas G.R. et al. | Year: 1985 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Evaluation of Mutagenicity Testing with Salmonella typhimurium TA102 in Three Different Laboratories. | Author: Mueller W. et al. | Year: 1993 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Collaborative study of mutagenicity with Salmonella typhimurium TA102. | Author: Jung R. et al. | Year: 1992 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Induction of chromosome aberrations and sister-chromatid exchanges by caprolactam in vitro. | Author: Norppa H. & Jaerventaus H. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Tests for the induction of chromosomal aberrations in human peripheral lymphocytes in culture. | Author: Howard C.A. et al. | Year: 1985 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Tests for the induction of DNA-repair synthesis in primary cultures of adult rat hepatocytes. | Author: Probst G.S. & Hill L.E. | Year: 1985 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosomal damage induced by caprolactam in human lymphocytes | Author: Sheldon T. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome Aberration and Sister Chromatid Exchange Tests in Chinese Hamster Ovary Cells In Vitro III: Results With 27 Chemicals | Author: Gulati D.K. et al. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Tests for the induction of chromosomal aberrations and sister chromatid exchanges in cultured Chinese hamster ovary (CHO) cells. | Author: Gulati D.K. et al. | Year: 1985 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: In Vitro Mutagenicity and Cell Transformation Screening of Caprolactam. | Author: Allied Chemical Corp. (ACC) | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: In Vitro Mutagenicity and Cell Transformation Screening of Caprolactam. | Author: Greene E.J. et al. | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: NTP technical report on the carcinogenesis bioassay of Carpolactam (Cas No. 105-60-2) in F344 rats and B6C3F1 mice. | Author: National Toxicology Program (NTP) | Year: 1982 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Industrial Hygiene Orientating Investigation | Author: BASF AG Department of Toxicology | Year: 1965 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Industrial Hygiene Orientating Investigation | Author: BASF AG Department of Toxicology | Year: 1965 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Report on the testing of oral toxicity of Laurinlactam in rabbits and cats in comparison to Caprolactam. | Author: BASF AG Department of Toxicology | Year: 1965 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report on the testing of oral toxicity of Laurinlactam in rabbits and cats in comparison to Caprolactam. | Author: BASF AG Department of Toxicology | Year: 1965 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: epsilon-Caprolactam: Testing of acute oral toxicity in male and female Wistar rats. | Author: Bayer AG Institute of Toxicology | Year: 1987 | Guideline: B.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: epsilon-Caprolactam: Testing of acute oral toxicity in male and female Wistar rats. | Author: Bayer AG Institute of Toxicology | Year: 1987 | Guideline: B.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute inhalation toxicity LC50 4 h (rat) Liquid-aerosol-test from Caprolactam. | Author: BASF AG Department Toxicology | Year: 1985 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Acute inhalation toxicity LC50 4 h (rat) Liquid-aerosol-test from Caprolactam. | Author: BASF AG Department Toxicology | Year: 1985 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: E-Caprolactam: Testing of acute dermal toxicity in male and female Wistar rats. | Author: Bayer AG Institute of Toxicology | Year: 1987 | Guideline: 84/449/EW | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: E-Caprolactam: Testing of acute dermal toxicity in male and female Wistar rats. | Author: Bayer AG Institute of Toxicology | Year: 1987 | Guideline: 84/449/EW | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Examination of the absorption and elimination kinetics of e-Caprolactam after inhalation in rats. | Author: Bayer AG Institute of Toxicology | Year: 1977 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Examination of the absorption and elimination kinetics of e-Caprolactam after inhalation in rats. | Author: Bayer AG Institute of Toxicology | Year: 1977 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The Distribution of 14C-Caprolactam in Male Female and Pregnant Mice. | Author: Department of Pharmacology and Toxicology University of Louisville Kentucky | Year: 1981 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The distribution of [14C]caprolactam in male female and pregnant mice. | Author: Waddell W.J. et al. | Year: 1984 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition of (14C) Caprolactam in the rat. | Author: Unger P.D., Salerno A.J. & Friedman M.A. | Year: 1981 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition of (14C) Caprolactam in the rat. | Author: Unger P.D., Salerno A.J. & Friedman M.A. | Year: 1981 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Subchronic Inhalation Toxicity Study of Caprolactam (with a 4-Week Recovery) in the Rat via Whole-Body Exposures. | Author: Reinhold R.W. et al. | Year: 1988 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Report on the study of acute toxicity of Caprolactam to Rainbow trout | Author: BASF AG | Year: 1987 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Report on the study of acute toxicity of Caprolactam to Rainbow trout | Author: BASF AG | Year: 1987 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicity test of epsilon-Caprolactam with Medaka (Oryzias latipes) | Author: Japanese Ministry of Environment | Year: 2002 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute immobilisation test of e-Caprolactam with Daphnia magna | Author: Japanese Ministry of Environment | Year: 2002 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Determination of the acute toxicity of Caprolactam to the water flea Daphnia magna Straus | Author: BASF SE | Year: 1988 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Determination of the acute toxicity of Caprolactam to the water flea Daphnia magna Straus | Author: BASF SE | Year: 1988 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Growt inhibition of e-Caprolactam with Selenastrum capricornutum | Author: Japanese Ministry of Environment | Year: 2002 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Growth inhibiton test with Pseudomonas putida | Author: BASF SE | Year: 1988 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Growth inhibiton test with Pseudomonas putida | Author: BASF SE | Year: 1988 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan | Author: Japan Chemical Industry Ecology-Toxicology & Information Center | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |