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CAS 108-31-6 | Data Package 100 - 1000 t/a

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Includes:

Study name Short Description Data Owner
Appearance/physical state/colour Robust Study Summary -- Title: The Merck Index - An Encyclopedia of Chemicals Drugs and Biologicals.13th Edition | Author: O'Neil M.J. (ed.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (92nd Edition) | Author: Haynes W.M. (Ed.) Lide D.R. (Associate Editor) | Year: 2011 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Melting point/freezing point Robust Study Summary -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2001 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2001 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2003 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2003 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Robust Study Summary -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2006 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Melting point/freezing point Right to refer to study -- Title: Dynamische Differenzkalorimetrie (DSC) | Author: BASF AG | Year: 2006 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Right to refer to study -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 1983 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Boiling point Robust Study Summary -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 2006 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Boiling point Right to refer to study -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 2006 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Density Robust Study Summary -- Author: Gevorkyan A.A. et al | Year: 1983 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Density Robust Study Summary -- Title: The Merck Index - An Encyclopedia of Chemicals Drugs and Biologicals. 13th Edition | Author: O'Neil M.J. (ed.) | Year: 2001 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Vapour pressure Right to refer to study -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 1983 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Vapour pressure Robust Study Summary -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 2006 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Vapour pressure Right to refer to study -- Title: Dampfdruck Maleinsäureanhydrid | Author: BASF AG | Year: 2006 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Water solubility Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Stability: Dissociation constant Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 112 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Flammability Robust Study Summary -- Title: Evaluation ofphysical and chemical properties according to Regulation (EC) No 440/2008 | Author: BASF SE | Year: 2010 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Flammability Right to refer to study -- Title: Evaluation ofphysical and chemical properties according to Regulation (EC) No 440/2008 | Author: BASF SE | Year: 2010 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: Laborbericht Maleinsäureanhydrid Reizversuche am weißen Kaninchen | Author: BASF AG | Year: 1955 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Right to refer to study -- Title: Laborbericht Maleinsäureanhydrid Reizversuche am weißen Kaninchen | Author: BASF AG | Year: 1955 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Skin irritation / corrosion Robust Study Summary -- Title: Skin corrosion potential of maleic anhydride | Author: Chevron Chemical Company | Year: 1976 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin irritation / corrosion Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eye irritation Right to refer to study -- Title: Laborbericht Maleinsäureanhydrid Reizversuche am weißen Kaninchen | Author: BASF AG | Year: 1955 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eye irritation Robust Study Summary -- Title: Primary Eye Irritancy Study of Maleic Anhydride in Rabbits. | Author: Johnson W. | Year: 1991 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eye irritation Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Skin sensitisation Robust Study Summary -- Title: Characterization in mice of the immunological properties of five allergenic acid anhydrides | Author: Dearman R.J. et al. | Year: 2000 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Skin sensitisation Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid | Author: OECD | Year: 2004 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Gene Mutation Assay In Chinese Hamster V79 Cells in vitro (V79 / HPRT) with maleic acid | Author: Wollny H.E. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -
in vitro gene mutation study in mammalian cells Right to refer to study -- Title: Gene Mutation Assay In Chinese Hamster V79 Cells in vitro (V79 / HPRT) with maleic acid | Author: Wollny H.E. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Salmonella mutagenicity test results for 250 chemicals | Author: Haworth S.T. et al. | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: G06: Ames Summary Data Test Compound: Maleic anhydride CAS Number: 108-31-6 | Author: NTP | Year: 1980 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Genetic toxicity in vivo Robust Study Summary -- Title: In vivo Bone Marrow Chromosome study in rats (Inhalation exposure) in Rats Maleic Anhydride | Author: Farrow M.G. | Year: 1983 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Genetic toxicity in vivo Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Acute toxicity: oral Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Acute toxicity: oral Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid | Author: OECD | Year: 2004 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions. | Author: Vernot E.H. et al. | Year: 1977 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth HF et al. | Year: 1962 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Acute toxicity: dermal Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Basic toxicokinetics Robust Study Summary -- Title: Plasma level of maleic anhydride in dogs fed 60 mg/kg/day for 90 days | Author: Braun W. et al. | Year: 1975 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Basic toxicokinetics Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Repeated dose toxicity: oral Robust Study Summary -- Title: 90-Day dietary feeding studies on maleic anhydride in beagle dogs | Author: Humiston C.G et al. | Year: 1975 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Repeated dose toxicity: oral Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: Four-week inhalation study in rats (IRD-77-108) | Author: Goldenthal E.I. et al | Year: 1979 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Repeated dose toxicity: inhalation Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Toxicity to reproduction Robust Study Summary -- Title: Three Generation Reproduction Study in Rats (Modified to a Two Generation Study) | Author: Short R.D. | Year: 1982 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Teratology and multigeneration reproduction studies with maleic anhydride in rats | Author: Short R.D. et al | Year: 1986 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to reproduction Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Maleic acid: Daphnia magna acute immobilisation test | Author: Indrani B.K. | Year: 2010 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Maleic acid: Daphnia magna acute immobilisation test | Author: Indrani B.K. | Year: 2010 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Maleic acid: Alga growth inhibition test | Author: Bopanna MS | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Maleic acid: Alga growth inhibition test | Author: Bopanna MS | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Hydrolysis Robust Study Summary -- Title: The hydrolysis of carboxylic anhydrides. Part III. Reactions in initially neutral solutions | Author: Bunton C. A. et al. | Year: 1963 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Forschungsbericht Bewertung wassergefährdender Stoffe im Hinblick auf Lagerung Umschlag und Transport und Untersichung zur Abklärung substanz- und bewertungsmethodenspezifischer Grenzfälle bei der Bewertung wassergeährdender Stoffe | Author: Trenel J; Kuehn R | Year: 1982 | Guideline: 301 A-F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Maleic acid: Ready Biodegradability CO2 Evolution Test | Author: Department of Safety Assessment Advinus Therapeutics Private Limited | Year: 2010 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Right to refer to study -- Title: Maleic acid: Ready Biodegradability CO2 Evolution Test | Author: Department of Safety Assessment Advinus Therapeutics Private Limited | Year: 2010 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals based on the CSCL Japan | Author: Japan Chemical Industry Ecology-Toxicology & Information Center (JETOC) | Year: 1992 | Guideline: 301 A-F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Partition coefficient Robust Study Summary -- Title: Maleic Anhydride and Maleic Acid SIDS Initial Assessment Report For SIAM 18 | Author: OECD SIDS | Year: 2004 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Hydrolysis Robust Study Summary -- Title: The hydrolysis of carboxylic anhydrides. Part III. Reactions in initially neutral solutions | Author: Bunton C. A. et al. | Year: 1963 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -