You are here: Home> Turkey>TR-REACH>CAS 111-84-2> CAS 111-84-2 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: Halterman Products | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: No information | Author: Halterman Products | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Waiver | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products, Site Speyer, Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products Site Speyer Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products, Site Speyer, Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products, Site Speyer, Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products Site Speyer Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products Site Speyer, Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Explosive properties | Waiver | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Stability in organic solvents and identity of relevant degradation products | Waiver | - |
| Phys-Chem | Stability: Dissociation constant | Waiver | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products Site Speyer Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Data collection sheet 'Erfassung_Category_7' | Author: Haltermann Products Site Speyer Branch of Dow Olefinverbung GmbH | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Handbook of chemistry and physics. 86 th ed. | Author: Lide D.R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Waiver | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of gasoline: kinetics, mass balance and fate of individual hydrocarbons | Author: Solano-Serena et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Test Material: MRD-96-562 and MRD-96-587. 'Ready Biodegradability: 'Manometric Respiratory Test'. Final Report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1998 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Test Material: MRD-96-562 and MRD-96-587. 'Ready Biodegradability: 'Manometric Respiratory Test'. Final Report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1998 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Test Material: MRD-96-562 and MRD-96-587. 'Ready Biodegradability: 'Manometric Respiratory Test'. Final Report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1998 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
- |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Test Material: MRD-96-562 and MRD-96-587. 'Ready Biodegradability: 'Manometric Respiratory Test'. Final Report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1998 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: SBP 80/95 LNH: An assessment of 'ready' biodegradability | Author: Shell Chemicals Europe BV | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% hexane) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: SBP 80/95 LNH: An assessment of 'ready' biodegradability | Author: Shell Chemicals Europe BV | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% hexane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Photo-oxidation of crude oils. | Author: Nagata S. and Kondo G. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Microbial degradation of high-molecular-weight alkanes | Author: Haines J.R. and Alexander M. | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Cometabolic biodegradation of methyl tert-butyl ether by a soil consortium: Effect of components present in gasoline. | Author: Garnier P. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of gasoline: kinetics, mass balance and fate of individual hydrocarbons | Author: Solano-Serena et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Microbial degradation of oil and petrochemicals in the sea. | Author: McKenzie P. and Hughes D. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Oxidative abilities of benzene acclimated activated sludge | Author: Malaney G. and Mckinney R. | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Structural determinants in the oxidation of aliphatic compounds by activated sludge | Author: Gerhold R. and Malaney G. | Year: 1966 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Environmental | Biodegradation in soil | Waiver | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Quantitative structure-activity relationships for the effect of hydrophobic organic chemicals on rate of feeding by mussels (Mytilus edulis) | Author: Donkin P. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Prediction of the Sorption of Organic Compounds into Soil Organic Matter from Molecular Structure | Author: Schüürmann et al | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish, Acute Toxicity Test. Test Substance: MRD-00-624 | Author: ExxonMobil Chemical | Year: 2004 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 927-510-4 | Hydrocarbons, C7, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish, Acute Toxicity Test. Test Substance: MRD-00-624 | Author: ExxonMobil Chemical | Year: 2004 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS N/A | EC 927-510-4 | Hydrocarbons, C7, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish, Acute Toxicity Test. Rainbow Trout - Renewal | Author: CEFIC | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish, Acute Toxicity Test. Rainbow Trout - Renewal | Author: CEFIC | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish, Acute Toxicity Test | Author: European Chemical Industry Council CEFIC | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish, Acute Toxicity Test | Author: European Chemical Industry Council CEFIC | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 921-728-3 | Hydrocarbons, C7-C9, isoalkanes) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
- |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 919-389-1 | hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 919-389-1 | hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Results of the investigation of 200 compounds for acute fish toxicity with the golden orf test (Ergebnisse der Untersuchung von 200 chemischen Verbindungen auf akute Fishchtoxizitat mit dem Goldorfentest). | Author: Juhnke I. and Luedemann D. | Year: 1978 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Effects of some components of crude oil on young coho salmon | Author: Morrow J. et al. | Year: 1975 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Toxicity to Gambusia affinis of certain pure chemicals in turbid waters | Author: Wallen et al. | Year: 1957 | Klimisch score: 3 - Not reliable | Adequacy: other information. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (EC 919-389-1 | hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (EC 919-389-1 | hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, < 5% n-hexane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A Progress report for 1986. For: Ministry of Housing, Physical Planning and Environment | Author: Adema D.M.M. and van den Bos Bakker G.H. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 565-75-3 | EC 209-292-6 | 2,3,4-trimethylpentane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: A 48-hour static-acute immobilization test with the cladoceran (Daphnia magna). Unpublished study | Author: Shell Chemicals Europe B.V. | Year: 2000 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: A 48-hour static-acute immobilization test with the cladoceran (Daphnia magna). Unpublished study | Author: Shell Chemicals Europe B.V. | Year: 2000 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Quantitative structure-activity relationships for the effect of hydrophobic organic chemicals on rate of feeding by mussels (Mytilus edulis). | Author: Donkin P. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic toxicity of compounds that may be carried by ships (Marpol 1973, Annex II). A Progress report for 1986. For: Ministry of Housing, Physical Planning and Environment | Author: Adema D.M.M. and van den Bos Bakker G.H. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 565-75-3 | EC 209-292-6 | 2,3,4-trimethylpentane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute lethal toxicity of hydrocarbons and chlorinated hydrocarbons to two planktonic crustaceans: The key role of organism-water partitioning. | Author: Abernethy S. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: A predictive correlation for the acute toxicity of hydrocarbons and chlorinated hydrocarbons to the water flea (Daphnia magna) | Author: Bobra A. et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Results of the damaging effect of water pollutants on Daphnia magna (Befunde der Schadwirkung wassergefahrdender Stoffe gegen Daphnia magna). | Author: Bringmann G. and Kühn R. | Year: 1977 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The effect of Alaskan crude oil and selected hydrocarbon compounds on embryonic development of the Pacific oyster, Crassostrea gigas. UMI Dissertation Services, Ann Arbor, MN, USA. | Author: Legore R. | Year: 1974 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: A 96-hour toxicity test with the freshwater alga (Selenastrum capricornutum) | Author: Shell Chemicals Europe B.V. | Year: 2000 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: A 96-hour toxicity test with the freshwater alga (Selenastrum capricornutum) | Author: Shell Chemicals Europe B.V. | Year: 2000 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: OECD SIDS - Category: C7-C9 Aliphatic hydrocarbon solvents | Author: IHSC American Chemistry Council | Year: 2009 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: SBP 80:95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: SBP 100/140: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1995 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: SBP 60/95 LNH: Acute toxicity of water accomodated fractions to Oncorhynchus mykiss, Daphnia magna, and Raphidocelis subcapitata | Author: Shell Chemicals Europe BV | Year: 1994 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS N/A | EC 921-024-6 | Hydrocarbons, C6-C7, n-alkanes, isoalkanes, cyclics, <5% n-hexane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Gulf Underwater Flare Experiment (GUFEX): Effects of Hydrocarbons on Phytoplankton. | Author: Brooks J. | Year: 1977 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. Read-Across (CAS 111-65-9 | EC 203-892-1 | octane) |
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| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Determination and Interpretation of hydrocarbon toxicity to ciliate protozoa. | Author: Rogerson A. | Year: 1983 | Klimisch score: 3 - Not reliable | Adequacy: other information | GLP: N. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman A.D. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman A.D. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Inhalation kinetics of C6 to C10 aliphatic, aromatic and naphthenic hydrocarbons in rat after repeated exposures | Author: Zahlsen K. et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Accumulation and distribution of aliphatic (n-nonane), aromatic (1,2,4-trimethylbenzene) and naphtenic (1,2,4-trimethylcyclohexane) hydrocarbons in the rat after repeated inhalation. | Author: Zahlsen K. et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicity of n-C9 to n-C13 alkanes in the rat on short term inhalation. | Author: Nilsen O.G et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Uptake of 19 hydrocarbon vapor inhaled by F344 rats. | Author: Dahl A.R. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: In vitro dermal absorption rate testing of certain chemicals of interest to the occupational safety and health administration: Summary and evaluation of USEPA's mandated testing. | Author: Fasano W.J. and McDougal J.N. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane / 142-82-5 / 205-563-8; heptane) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute Oral Toxicity Study in Rats. Isooctane. Final Report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute Oral Toxicity Study in Rats. Isooctane. Final Report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Toxicity of n-C9 to n-C13 alkanes in the rat on short term inhalation. | Author: Nilsen O.G et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Petroleum hydrocarbon toxicity studies XVII. Animal response to n-nonane vapor. | Author: Carpenter C.P. et al. | Year: 1978 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute Dermal Toxicity Study in Rabbits. Isooctane. Final Report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute Dermal Toxicity Study in Rabbits. Isooctane. Final Report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary Skin Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary Skin Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane and tetradecane | Author: Babu R.J. et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Washed Primary Eye Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Eye irritation | Right to refer to study -- Title: Washed Primary Eye Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Eye irritation | Robust Study Summary -- Title: Unwashed Primary Eye Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Eye irritation | Right to refer to study -- Title: Unwashed Primary Eye Irritation Study in Rabbits. Isooctane. Final report | Author: Chevron Phillips Chemicals International NV | Year: 1982 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Eye irritation | Waiver | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: The acute toxicity of SBP 100/140 | Author: Shell Chemicals Europe B.V. | Year: 1977 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: The acute toxicity of SBP 100/140 | Author: Shell Chemicals Europe B.V. | Year: 1977 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS N/A | EC 920-750-0 | Hydrocarbons, C7-C9, n-alkanes, isoalkanes, cyclics) |
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| Toxicological | Skin sensitisation | Waiver | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: A Combined Repeated Dose Toxicity Study With The Reproduction/Developmental Toxicity Screening Test In Sprague Dawley Rats By The Oral Route | Author: Sasol | Year: 1995 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 124-18-5 | EC 204-686-4 | decane) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: A Combined Repeated Dose Toxicity Study With The Reproduction/Developmental Toxicity Screening Test In Sprague Dawley Rats By The Oral Route | Author: Sasol | Year: 1995 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 124-18-5 | EC 204-686-4 | decane) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 90-Day Oral Toxicity Study on n-Nonane in Female Fisher 344 Rats and Male C57BL/6 Mice | Author: Dodd D.R. et al. | Year: 2003 | Guideline: 408 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Waiver | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicity evaluation of petroleum blending streams: inhalation subchronic toxicity/neurotoxicity study of a light alkylate naphtha distillate in rats | Author: Schreiner C. et al. | Year: 1998 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 64741-66-8 | EC 265-068-8 | Naphtha (petroleum), light alkylate) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Petroleum hydrocarbon toxicity studies XVII. Animal response to n-nonane vapor | Author: Carpenter C.P. et al. | Year: 1978 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 12 week Inhalation Toxicity Study of MRD-77-44 in the Rat | Author: ExxonMobil | Year: 1978 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. Read-Across (CAS N/A | EC 926-952-5 | Hydrocarbons, C9-C11, isoalkanes, cyclics, < 2% aromatics) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 12 week Inhalation Toxicity Study of MRD-77-44 in the Rat | Author: ExxonMobil | Year: 1978 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. Read-Across (CAS N/A | EC 926-952-5 | Hydrocarbons, C9-C11, isoalkanes, cyclics, < 2% aromatics) |
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| Toxicological | Repeated dose toxicity: dermal | Waiver | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Toxicity studies with hydrocarbon solvents: in vitro genotoxicity studies with heptane. | Author: Shell Chemicals Eurpope B.V. | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Toxicity studies with hydrocarbon solvents: in vitro genotoxicity studies with heptane. | Author: Shell Chemicals Eurpope B.V. | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks T.M. et al. | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks T.M. et al. | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals | Author: Zeiger E. et al. | Year: 1992 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Toxicity studies with hydrocarbon solvents: in vitro genotoxicity studies with heptane. | Author: Shell Chemicals Eurpope B.V. | Year: 1983 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Toxicity studies with hydrocarbon solvents: in vitro genotoxicity studies with heptane. | Author: Shell Chemicals Eurpope B.V. | Year: 1983 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks T.M. et al. | Year: 1988 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks T.M. et al. | Year: 1988 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 142-82-5 | EC 205-563-8 | Heptane) |
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| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Assessment of the genotoxic potential of unleaded gasoline and 2,2,4-trimethylpentane in human lymphoblasts in vitro. | Author: Richardson K. et al. | Year: 1986 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: A Combined Repeated Dose Toxicity Study With The Reproduction/Developmental Toxicity Screening Test In Sprague Dawley Rats By The Oral Route | Author: Sasol | Year: 1995 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: Y. Read-Across (CAS 124-18-5 | EC 204-686-4 | decane) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: A Combined Repeated Dose Toxicity Study With The Reproduction/Developmental Toxicity Screening Test In Sprague Dawley Rats By The Oral Route | Author: Sasol | Year: 1995 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: Y. Read-Across (CAS 124-18-5 | EC 204-686-4 | decane) |
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| Toxicological | Toxicity to reproduction | Waiver | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Inhalation developmental toxicity and reproduction studies with cyclohexane | Author: Kreckmann K.H. et al. | Year: 2000 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 110-82-7 | EC 203-806-2 | cyclohexane) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: A segment II teratology study in rats following inhalation exposure to MRD-78-25 and MRD-78-26. Final report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (hydrocarbons, C7-C9, isoalkanes) |
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| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: A segment II teratology study in rats following inhalation exposure to MRD-78-25 and MRD-78-26. Final report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (hydrocarbons, C7-C9, isoalkanes) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: A segment II teratology study in rats following inhalation exposure to MRD-77-44 | Author: ExxonMobil | Year: 1978 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. Read-Across (CAS N/A | EC 926-952-5 | Hydrocarbons, C9-C11, isoalkanes, cyclics, < 2% aromatics) |
- |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: A segment II teratology study in rats following inhalation exposure to MRD-77-44 | Author: ExxonMobil | Year: 1978 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. Read-Across (CAS N/A | EC 926-952-5 | Hydrocarbons, C9-C11, isoalkanes, cyclics, < 2% aromatics) |
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| Toxicological | Developmental toxicity/teratogenicity | Waiver | - |