You are here: Home> Turkey>TR-REACH>CAS 111-90-0> CAS 111-90-0 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Hazardous Substances Databank | Author: National Library of Medicine USA | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Hawley's Condensed Chemical Dictionary 12th ed | Author: Lewis RJ (Ed) | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals 3rd ed | Author: Verschueren K (Ed) | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals 3rd ed | Author: Verschueren K (Ed) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: User's guide for EPIWIN version 3.05 | Author: Meylan W | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Merck Index Online | Author: Merck | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide DR (editor) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Users's guide for EPIWIN version 3.05 | Author: Meylan W | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Organic Solvents Physical Properties and Methods of Purification | Author: Riddick JA, Bunger WB, Sakano TK | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals 3rd ed | Author: Verschueren K (Ed) | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: No information | Author: The Dow Chemical Company | Year: 1950 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide DR (editor) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Merck Index online | Author: No author provided | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals 3rd ed | Author: Verschueren K (Ed) | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Organic Solvents Physical Properties and Methods of Purification | Author: Riddick JA, Bunger WB, Sakano TK | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Diethylene glycol ether: determination of surface tension | Author: Paula MC | Year: 2017 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 75th ed | Author: Lide DR (editor) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: NFPA 325 Guide to Fire Hazard Properties of Flammable Liquids Gases and Volatile Solids | Author: National Fire Protection Association | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Organic solvents: Physical properties and methods of purification 4th ed | Author: Riddick JA et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Merck Index online | Author: No author provided | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Hawley's Condensed Chemical Dictionary 12th ed | Author: Lewis RJ (Ed | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: User's guide for EPIWIN version 3.05 | Author: Meylan W | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: EPISUITE v 4.11 | Author: US EPA | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals 3rd ed | Author: Verschueren K (Ed) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Organic Solvents Physical Properties and Methods of Purification | Author: Riddick JA, Bunger WB, Sakano TK | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Patty's Toxicology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: NFPA 325 Guide to Fire Hazard Properties of Flammable Liquids Gases and Volatile Solids | Author: National Fire Protection Association | Year: 1994 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 1998 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Solvents for Industry | Author: BP Chemicals | Year: 1982 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Hazardous Substances Databank | Author: US National Library of Medicine | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: NFPA 325 Guide to Fire Hazard Properties of Flammable Liquids Gases and Volatile Solids | Author: National Fire Protection Association | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: IUCLID chemical data sheet - 2-(2-ethoxyethoxy)ethanol | Author: No author provided | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Directory of Solvents | Author: Whim BP, Johnson PG (eds) | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Patty's Toxiciology 5th ed chapter 86 | Author: Bingham E, Cohrssen B, Powell CH (eds) | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Carbitol solvent low gravity. Acute toxicity and primary irritancy studies | Author: The Dow Chemical Company | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes | Author: Draize JH et al. | Year: 1944 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Comparative toxicity of nine glycol ethers II. Acute dermal LD50 | Author: Krasavage WJ, Terhaar CJ | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Report No.XV/333 | Author: BASF AG | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Arch Dermatol Syph 45 553-559 cited in VCI BASF Hoechst Existing Substances data for the review of effects on man and environment | Author: Cranch AG et al. | Year: 1942 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Information from a secondary source only. Original study not reviewed. Included for completion purposes only as available data. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Comparison of the toxic hypnotic and irritating properties of eight organic solvents | Author: Latven AR et al. | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Information from a secondary source only. Original study not reviewed. Included for completion purposes only as available data. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: An objective method for the evaluation of eye irritation in vivo | Author: Jacobs G, Martens M | Year: 1989 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Evaluation of the enucleated eye test against in vivo eye irritation test in the rabbit | Author: Jacobs G, Martens M | Year: 1987 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report No.XV/333 | Author: BASF AG | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Chemical burns of the rabbit cornea | Author: Carpenter H.F and Smyth C.P. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Comparison of the toxic hypnotic and irritating properties of eight organic solvents | Author: Latven AR | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Carbitol solvent low gravity. Acute toxicity and primary irritancy studies | Author: The Dow Chemical Company | Year: 1984 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Evaluation of ocular irritation in the rabbit: objective versus subjective assessment | Author: Conquet P | Year: 1977 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Evaluation of ocular irritation in the rabbit: development of an objective method of studying eye irritation | Author: Lailler J | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Arch Gewerbehyg 11 326-344 [Grant's Toxicology of the Eye 3rd Edition 1986] | Author: Walther R | Year: 1942 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: No information | Author: Sanderson DM | Year: 1959 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: No information | Author: Cranch AG | Year: 1942 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: No information | Author: Walther R | Year: 1942 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: No information | Author: Von Oettingen et al. | Year: 1931 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Safety assessment of the pharmacological excipient diethylene glycol monoethyl ether (DEGEE) using in vitro and in vivo systems | Author: Srivastava S et al. | Year: 2019 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Comparative toxicity of nine glycol ethers: I. Acute oral LD50 | Author: Krasavage WJ, Terhaar CJ | Year: 1981 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Comparative toxicity of nine glycol ethers: I. Acute oral LD50 | Author: Krasavage WJ, Terhaar CJ | Year: 1981 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report No.XV/333 | Author: BASF AG | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Further experience with the range finding test in the industrial toxicology laboratory | Author: Smyth H.F. and Carpenter C.P. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Summary of the toxicity of the glycols and their derivatives. 8. Single doses of 'Carbitol' (mono ethyl ether of diethylene glycol) by mouth | Author: The Dow Chemical Company | Year: 1938 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The single dose toxicity of some glycols and derivatives | Author: Smyth HF, Seaton J, Fischer L | Year: 1941 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: In vivo and in vitro toxicity of Carbitol [Boll chim Farm 125 401-403. 1986] | Author: Berte F et al. | Year: 1986 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Data for the substantiation of the maximum permissible concentration of the monoethyl ether of diethylene glycol in reservoir water [Gig Samit (4) 74-76 1981] | Author: Kondratyuk VA et al. | Year: 1981 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The toxicology of some glycols and derivatives | Author: Lang et al. | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute toxicity and general systemic actions of diethyleneglycol monoethylether (Carbitol) | Author: Hanzlik PJ et al. | Year: 1947 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Comparison of the toxic hypnotic and irritating properties of eight organic solvents | Author: Latven AR et al. | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The toxicology of some glycols and derivatives | Author: Lang EP et al. | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: American Scientist 32 103-119 | Author: Calvery HO | Year: 1944 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Data for the substantiation of the maximum permissible concentration of the monoethyl ether of diethylene glycol in reservoir water [Gig Samit (4) 74-76 1981] | Author: Kondratyuk VA et al. | Year: 1981 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Results of range finding toxicological studies on some of the dowanols | Author: The Dow Chemical Company | Year: 1947 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Comparative inhalation teratology of four glycol ether solvents and an amino acid derivative in rats. | Author: Nelson BK et al. | Year: 1984 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The toxicology of some glycols and derivatives | Author: Lang EP et al. | Year: 1939 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Statistics vs safety factor and scientific judgement in the evaluation of safety for man | Author: Weil CS | Year: 1972 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Studies of oral acute toxicities of diethylene glycol monoethyl ether (DEGM) in the rat [Kent Neupo Tokyo Toritsu Eisei Kenkyusho (39) 295-298. 1988.] Chem Abstr 110 (19) 167679. 1989 | Author: Ichikawa H et al. | Year: 1988 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range finding tests on low gravity 'Carbitol' | Author: The Dow Chemical Company | Year: 1951 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Summary of the toxicity of the glycols and their derivatives. 65. Single doses of 'Carbitol' by mouth to rabbits | Author: The Dow Chemical Company | Year: 1940 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Carbitol solvent low gravity acute toxicity and primary irritancy studies | Author: The Dow Chemical Company | Year: 1984 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Report No.XV/333 | Author: BASF AG | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Carbitol solvent low gravity. Acute toxicity and primary irritancy studies | Author: The Dow Chemical Company | Year: 1984 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Diethylene glycol monoethyl ether - acute inhalation study in rats 4 hour exposure | Author: Kenny TJ et al.. | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Comparative toxicity of nine glycol ethers: II acute dermal LD50 | Author: Krasavage WJ, Terhaar CJ | Year: 1981 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Carbitol Solvent low gravity. Acute toxicity and primary irritation studies. | Author: The Dow Chemical Company | Year: 1984 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Summary of the toxicity of the glycols and their derivatives. 14. Single doses of 'carbitol' butyl 'carbitol' and glycerine by skin absorption | Author: The Dow Chemical Company | Year: 1938 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: The effect of 'carbitol' upon the intact external surfaces of the body including some comprisons with glycerine and ethyl alcohol | Author: The Dow Chemical Company | Year: 1940 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Summary of the toxicity of the glycols and their derivatives. 89. Skin absorption of 'Carbitol' | Author: The Dow Chemical Company | Year: 1941 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: American Scientist 32 103-119 | Author: Calvery HO | Year: 1944 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Comparative chronic toxicity of diethylene glycol monoethyl ether (Carbitol) and some related glycols: Results of continued drinking and feeding | Author: Hanzlik PJ et al. | Year: 1947 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: (2-Ethoxyethoxy)acetic acid: an unusual compound found in the gas chromatographic analysis of urinary organic acids | Author: Kamerling et al. | Year: 1977 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Glucuronic acid excretion after diethylene glycol monoethyl ether (Carbitol) and some other glycols | Author: Fellows et al. | Year: 1947 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Excretion and fate of diethylene glycol monoethyl ether (Carbitol) after epidermal and other methods of administration | Author: Luduena et al. | Year: 1947 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: Absorption of some glycol ethers through human skin in vitro | Author: Dugard PH et al. | Year: 1984 | Guideline: 428 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: 2-Methoxyethanol 2-(2-methoxyethoxy)ethanol 2-(2-ethoxyethoxy)ethanol 2-(2-butoxyethoxy)ethanol: absorption through human skin in vitro | Author: Walker M., Scott R.C. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: Evaluation of the transepidermal permeation of diethylene glycol monoethyl ether and skin water loss | Author: Ganem-Quintanar A et al. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Comparative toxicity of nine glycol ethers: III Six weeks repeated dose study | Author: Krasavage WJ, Vlaovic MS | Year: 1982 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Final report: Diethylene glycol monoehtyl ether: Reproduction and fertility assessment in CD-1 mice when administered in the drinking water | Author: National Toxicology Program | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Reproductive effects of diethylene glycol and diethylene glycol monoethyl ether in Swiss CD-1 mice assessed by a continuous breeding protocol | Author: Williams J | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Short-term toxicity of diethyleneglycol monoethylether in the rat mouse and pig. | Author: Gaunt IF et al. | Year: 1968 | Guideline: 409 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: NIOSH NTIS rep PB-83-257600 cited in VCI Hoechst BASF Existing substances data for the review of effects on man and environment | Author: Piccirillo VJ et al. | Year: 1983 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: The toxicology of glycols | Author: Walther R | Year: 1942 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Safety assessment of the pharmacological excipient diethylene glycol monoethyl ether (DEGEE) using in vitro and in vivo systems | Author: Srivastava S et al. | Year: 2019 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Twenty-eight-day repeated-dose inhalation exposure of rats to diethylene glycol monoethyl ether | Author: Hardy CJ et al. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Sanitary-toxicological characteristics of diethylene glycol ethers (Carbitols) used in air pollution control | Author: Krotov YA, Lykova SA, et al. | Year: 1981 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Comparative toxicity of ten organic chemicals to ten common aquatic species | Author: Thurston RV | Year: 1985 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The acute toxicity of 47 industrial chemicals to fresh and salt water fishes | Author: Dawson GW, Jennings AL, Drozdowski D et al. | Year: 1975 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: No information | Author: Lipnick RL et al. | Year: 1987 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Comparative toxicity of ten organic chemicals to ten common aquatic species | Author: Thurston RV | Year: 1985 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The acute toxicity of some petrochemicals to goldfish | Author: Bridie AL, Wolff CJM, Winter M | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Effects of Pollution on Freshwater Fish | Author: Spehar RL et al. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Toxicity of Dowanol DE to freshwater organisms | Author: The Dow Chemical Company | Year: 1979 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: The Pollutional Evaluation of Compounds | Author: The Dow Chemical Company | Year: 1975 | Klimisch score: 3 - Not reliable | Adequacy: disregarded due to major methodological deficiencies. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Environmental impact product analysis acute aquatic toxicity testing | Author: The Dow Chemical Company | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Toxicity of Dowanol DE to freshwater organisms | Author: The Dow Chemical Company | Year: 1979 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Comparative toxicity of ten organic chemicals to ten common aquatic species | Author: Thurston RV | Year: 1985 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: No information | Author: Jackim E | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Ecological fate and effects testing of UCC products and wastewaters during 1987 | Author: Dow Chemicals | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Comparative toxicity of ten organic chemicals to ten common aquatic species | Author: Thurston RV | Year: 1985 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Measurement of baseline toxicity and QSAR analysis of 50 non-polar and 58 polar narcotic chemicals for the algae Pseudokirchneriella subcapitata | Author: Aruoja V et al. | Year: 2014 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Glycol ethers: Summary of available ecological fate and effects data | Author: The Dow Chemical Company | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Ecological fate and effects testing of UCC products and wastewaters during 1987 | Author: The Dow Chemical Company | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Bacterial growth inhibition test | Author: Alsop GM, Waggy GT, Conway RA | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation testing of selected glycol ethers by carbon dioxide evolution test procedures | Author: The Dow Chemical Company | Year: 1998 | Guideline: 301B | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Brine Shrimp bioassay and seawater BOD of petrochemicals | Author: Price KS, Waggy GT, Conway RA | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Environmental Impact analysis product biodegradability testing | Author: Dow Chemicals | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: BOD and COD of some petrochemicals | Author: Bridié AL, Wolff CJM, Winter M | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Prufung der biologischen abbaubarkeit im standversuch - weitere erfahrungen und neue einsatzmoglichkeiten | Author: Zahn R Wellens H | Year: 1980 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biochemical degradation of synthetic detergents. II. Studies on the relation between chemical structure and biochemical oxidation | Author: Bogan RH | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers | Author: OECD | Year: 2005 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: BOD and COD of some petrochemicals | Author: Bridié AL et al. | Year: 1979 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: SIDS Initial Assessment Report for SIAM 21. Diethylene glycol ethers. | Author: OECD | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Glycol ethers: Summary of available ecological fate and effects data. | Author: The Dow Chemical Company | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Environmental impact analysis product biodegradability testing | Author: The Dow Chemical Company | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Robust Studies Summaries | Robust Studies Summaries package for all studies (10-100 tpa). | - |
| Chemical Safety Report | Chemical Safety Report | - |