You are here: Home> South Korea>K-REACH>CAS 1185-53-1> CAS 1185-53-1 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, Article No.: 108219, Boiling Point A.2 (OECD 103) | Author: T. Paesch | Year: 2015 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, Article No.: 108219, Boiling Point A.2 (OECD 103) | Author: T. Paesch | Year: 2015 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: T. Paesch | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: M. Krack | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: M. Krack | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: M. Krack | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: 2-amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride | Author: M. Krack | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride - Acute immobilization test in Daphnia magna | Author: Heusener, A. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride - Acute immobilization test in Daphnia magna | Author: Heusener, A. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Art. 108219 (TRIS-HCL Emprove Bio Bulk) - In Vitro Skin Irritation Test (Reconstructed Human Epidermis Model) | Author: Gado, A. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Art. 108219 (TRIS-HCL Emprove Bio Bulk) - In Vitro Skin Irritation Test (Reconstructed Human Epidermis Model) | Author: Gado, A. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride GR - Guinea pig maximization test according to Magnusson and Kligman | Author: Heusener, A. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride GR - Guinea pig maximization test according to Magnusson and Kligman | Author: Heusener, A. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride - Bacterial Mutagenicity Assay, Salmonella typhimurium and Escherichia coli | Author: D. Utesch | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro genetic toxicity | Right to refer to study -- Title: Art. 108219 Tris(hydroxymethyl)-aminomethane hydrochloride - Bacterial Mutagenicity Assay, Salmonella typhimurium and Escherichia coli | Author: D. Utesch | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |