You are here: Home> Turkey>TR-REACH>CAS 121-33-5> CAS 121-33-5 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: Budavari S. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: Lewis RJ | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology | Author: KIRK-OTHMER | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Sigma-Aldrich | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Budavari S. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Clayton G.D., Clayton F.E. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Inoue K. Et Al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Numata A. Et Al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Di Biase Et Al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Susuki Et Al. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Budavari S. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Verschueren K. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Weast R.C. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Clayton G.D., Clayton F.E. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology | Author: KIRK-OTHMER | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Clayton G.D., Clayton F.E. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Weast R.C. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Verschueren K. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Budavari S. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Density | Robust Study Summary -- Title: Encyclopedia of Chemical Technology | Author: KIRK-OTHMER | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Clayton G.D., Clayton F.E. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Clayton G.D., Clayton F.E. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Verschueren K. | Year: 1958 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determining the vapour pressures of plants volatiles from gas chromatographic retention data. | Author: Serpinskii et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Hoskovec M. et al. | Year: 1924 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: MANGE EHLER | Year: 1877 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: TIEMAN NAGAI | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Gangolli S. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: No information | Author: LEO A.J. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Using AM1 hamiltonian in prediction of benzaldehydes sorption on soil. | Author: Jin L. et al. | Year: 1998 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | Specialty Operations |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Prediction of partition coeffiicent and toxicity for benzaldehyde compounds by their capacity factors and various molecular descriptors | Author: Dai J. et al. | Year: 2001 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | Specialty Operations |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Prediction of octanol/water partitioning coefficient and sediment sorption coefficient for benzaldehydes by various molecular descriptors. | Author: Dai J., Xu M., Wang L. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: No information | Author: Robinson Kiang | Year: 1955 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: No information | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | Specialty Operations |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Determination of the particle size distribution of diphenols | Author: Masson J.C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | Specialty Operations |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Determination of the particle size distribution of diphenols | Author: Masson J.C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | Specialty Operations |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Epreuve de sensibilité à la friction pour le Rhovanil extra pure (nom chimique usuel Vanilline) | Author: Vicot P. | Year: 2008 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | Specialty Operations |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Epreuve de sensibilité à la friction pour le Rhovanil extra pure (nom chimique usuel Vanilline) | Author: Vicot P. | Year: 2008 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | Specialty Operations |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Flammability | Right to refer to study -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.10-13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.15-16 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of the flash point the auto-ignition temperature explosion properties flammability oxidizing properties of Vanilline. | Author: Vibert M. | Year: 2008 | Guideline: A.15-16 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Test to evaluate the acute toxicity following a single cutaneous application (limit test) in the rat | Author: Lheritier M. | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Test to evaluate the acute toxicity following a single cutaneous application (limit test) in the rat | Author: Lheritier M. | Year: 1991 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Acute eye irritation in rabbits | Author: Rokh N. | Year: 2007 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Eye irritation | Right to refer to study -- Title: Acute eye irritation in rabbits | Author: Rokh N. | Year: 2007 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | Eye irritation | Right to refer to study -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Test to evaluate the sensitizing potential in the guinea pig (Guinea-pig maximization test) | Author: Mercier O. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Test to evaluate the sensitizing potential in the guinea pig (Guinea-pig maximization test) | Author: Mercier O. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Human potency predictions for aldehydes using the local lymph node assay. | Author: Basketter D.A. et al. | Year: 2001 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Development and validation of an alternative dermal sensitization test: The mouse ear swelling test (MEST). | Author: Gad S.C. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Occupational contact dermatitis in manufacture of Vanillin. | Author: Wang Xia-Sheng et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity test on vanillin in Salmonella/mammalian-microsome reverse mutation assay (Ames test) | Author: Lawlor T.E. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity test on vanillin in Salmonella/mammalian-microsome reverse mutation assay (Ames test) | Author: Lawlor T.E. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Recherche de mutagenicité selon la technique de B.N. Ames sur le produit: Vanilline | Author: Marzin D. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Recherche de mutagenicité selon la technique de B.N. Ames sur le produit: Vanilline | Author: Marzin D. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals | Author: Mortelman K. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity testing in the Salmonella typhimurium assay of phenolic compounds and phenolic fractions obtained from smokehouse smoke condensates | Author: Pool B.L., Lin P.Z. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Primary mutagenicity screening of food additives currently used in Japan | Author: Ishidate M. et al. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Genotoxicity of flavouring agents | Author: Kasamaki A. et al. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Inhibitory effects of flavourings on mutagenesis induced by chemicals in bacteria | Author: Ohta T. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Antimutagenic effects of benzaldehyde and its derivatives on mutagenesis induced by 4-nitroquinoline 1-oxide in Escherichia coli | Author: Watanabe K., Ohta T., Shirasu Y. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Effect of vanillin on sister chromatid exchanges and chromosome aberrations induced by mitomycin C in cultured Chinese hamster ovary cells | Author: Sasaki Y..F et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Effects of antimutagenic flavourings on SCEs induced by chemical mutagen in culture Chinese hamster cells | Author: Sasaki Y..F et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Vanillin - In an in vitro cytogenetic assay measuring chromosomal aberration frequencies in chinese hamster ovary (CHO) cells | Author: Murli H. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Vanillin - In an in vitro cytogenetic assay measuring chromosomal aberration frequencies in chinese hamster ovary (CHO) cells | Author: Murli H. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Suppressing effect of antimutagenic flavourings on chromosome aberrations induced by UV-light or X-rays in cultured Chinese hamster cells | Author: Sasaki Y..F et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Inhibition of methotrexate-induced chromosomal damage by vanillin and chlorophyllin in V79 cells | Author: Keshava C. et al. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Different modifications by vanillin in cytotoxicity and genetic changes induced by EMS and H2O2 in cultured Chinese hamster cells | Author: Tamai K., Tezuka H., Kuroda Y. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Protective effect of vanillin on radiation-induced micronuclei and chromosomal aberrations in V79 cells | Author: Keshava C. et al. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Protective effect of vanillin on radiation-induced micronuclei and chromosomal aberrations in V79 cells | Author: Keshava C. et al. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Recherche d'une action mutagène par le test du micronucleus chez la souris du produit Vanilline | Author: Marzin D. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Recherche d'une action mutagène par le test du micronucleus chez la souris du produit Vanilline | Author: Marzin D. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Test to evaluate the acute toxicity following a single oral administration (LD50) in the rat | Author: Lheritier M. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Test to evaluate the acute toxicity following a single oral administration (LD50) in the rat | Author: Lheritier M. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Vanillin | Author: Birck M.D. | Year: 1976 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Vanillin: Acute Oral Administration | Author: Elsea J.R. | Year: 1955 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Vanillin: Acute Oral Administration | Author: Elsea J.R. | Year: 1955 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Test to evaluate the acute toxicity following a single cutaneous application (limit test) in the rat | Author: Lheritier M. | Year: 1991 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Test to evaluate the acute toxicity following a single cutaneous application (limit test) in the rat | Author: Lheritier M. | Year: 1991 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Specialty Operations |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Vanillin - FINAL REPORT - Chronic feeding in rats Chronic oral administration in dogs supplement to report dated February 15 1955 | Year: 1955 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Vanillin - FINAL REPORT - Chronic feeding in rats Chronic oral administration in dogs supplement to report dated February 15 1955 | Year: 1955 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Food flavourings and compounds of related structure. II. Subacute and chronic toxicity | Author: Hagan E.C. et al. | Year: 1967 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | Specialty Operations |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Evaluaution of certain food additives and contaminants. WHO Technical report series 909 | Author: WHO (World Health Organization) | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | Specialty Operations |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Contact allergy to balsam of Peru. II. Patch test results in 102 patients with selected balsam of Peru. | Author: Hausen B.M. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Multicentre study of allergic contact cheilitis from toothpastes. | Author: Francalanci S. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Toxicological | Sensitisation data (humans) | Robust Study Summary -- Title: Occupational contact dermatitis in manufacture of Vanillin. | Author: Wang Xia-Sheng et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) | Author: Brooke L.T. et al. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales promelas) | Author: Brooke L.T. et al. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | Specialty Operations |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicity of selected organic compounds to feathed minnows | Author: Mattson V.R. Et Al. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute toxicity in daphnia magna under static conditions | Author: Voltes C. | Year: 2009 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute toxicity in daphnia magna under static conditions | Author: Voltes C. | Year: 2009 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Algal growth inhibition test | Author: Voltes C. | Year: 2009 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Algal growth inhibition test | Author: Voltes C. | Year: 2009 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: CERI. Biodegradation and bioaccumulation of existing chemicals. | Author: MITI | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Tetratox: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. | Author: Schultz T.W. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: QSAR studies of comparative toxicity in aquatic organisms | Author: Cronin M.T.D., Dearden J.C., Dobbs A.J. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Toxicity of substituted benzaldehydes to Photobacterium phosphoreum and quantitative structure-activity relationship. | Author: Jin L. E Al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: The yeast test: an alternative method for the testing of acute toxicity of drug substances and environmental chemicals | Author: Koch H.P., Hofeneder M., Bohne B. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: No information | Author: Sierra-Alvarez R., Lettinga G. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Effect of Vanillin on the reproduction of Daphnia magna | Author: Källqvist T. | Year: 1996 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Specialty Operations |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Effect of Vanillin on the reproduction of Daphnia magna | Author: Källqvist T. | Year: 1996 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Borregaard |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and bioaccumulation of existing chemicals | Author: MITI | Year: 1993 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | Specialty Operations |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Aerobic biodegradation of Vanillin measured as BOD5/COD. | Author: Källqvist T. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | Specialty Operations |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Aerobic biodegradation of Vanillin measured as BOD5/COD. | Author: Källqvist T. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | Borregaard |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: The biological purification of waste products from olive oil extraction. | Author: Martinez N.L. Et Al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Specialty Operations |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Anaerobic biodegradation of eleven aromatic compounds to methane. | Author: Healy J.B., Young L.Y. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | Specialty Operations |