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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Waiver | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: FASCAT® 8231 Catalyst Material Safety Data Sheet | Author: Arkema Inc | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: FASCAT® 8231 Catalyst Material Safety Data Sheet | Author: Arkema Inc | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: determination of the boiling temperature of DOTE by differential scanning calorimetry | Author: Baltussen E | Year: 2010 | Guideline: A.2 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: determination of the boiling temperature of DOTE by differential scanning calorimetry | Author: Baltussen E | Year: 2010 | Guideline: A.2 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: EPI Suite Results For CAS 15571-58-1 | Author: EPI-WIN | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: EPI Suite Results For CAS 15571-58-1 | Author: EPI-WIN | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Material Safety Data Sheet THERMOLITE® 890 S STABILIZER | Author: Arkema Canada Inc. | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Material Safety Data Sheet THERMOLITE® 890 S STABILIZER | Author: Arkema Canada Inc. | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Baltussen E | Year: 2010 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Determination of the kinematic viscosity of dioctyltin bis (2-ethylhexylmercaptoacetate) | Author: Baltussen E. | Year: 2011 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Determination of the kinematic viscosity of dioctyltin bis (2-ethylhexylmercaptoacetate) | Author: Baltussen E. | Year: 2011 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Primary Eye Irritation Study of Dioctyltin bis(2-ethyl-hexylmercaptoacetate) in Albino Rabbits. | Author: Varsho B.J. | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Primary Eye Irritation Study of Dioctyltin bis(2-ethyl-hexylmercaptoacetate) in Albino Rabbits. | Author: Varsho B.J. | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary dermal irritation study of dioctyltin bis (2-ethyl-hexylmercaptoacetate) in albino rabbits | Author: Varsho B.J. | Year: 1996 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary dermal irritation study of dioctyltin bis (2-ethyl-hexylmercaptoacetate) in albino rabbits | Author: Varsho B.J. | Year: 1996 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute Dermal Irritation/Corrosion Study in the Rabbit. TK 10315/A (Irgastab 17 MOK-A) | Author: Anonymous | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute Dermal Irritation/Corrosion Study in the Rabbit. TK 10315/A (Irgastab 17 MOK-A) | Author: Anonymous | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Evaluation of skin sensitizing potential of DOTE using local lymph node assay: BrdU:ELISA | Author: Mrs. Kavita Patel | Year: 2016 | Guideline: 442B | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Evaluation of skin sensitizing potential of DOTE using local lymph node assay: BrdU:ELISA | Author: Mrs. Kavita Patel | Year: 2016 | Guideline: 442B | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute Oral Toxicity in the Rat. TK 10315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1992 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute Oral Toxicity in the Rat. TK 10315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1992 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The toxic effects of some di- and mono-n-octyl-tin compounds on white mice | Author: Pelikan Z. and E. Cerny | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute Dermal Toxicity in the Rat. TK 10315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1992 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute Dermal Toxicity in the Rat. TK 10315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1992 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Waiver | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Subchronic (90-day) toxicity studies with two organic tin compounds (Advastab 17 MOK 034 and Advastab 17 MOK 028) in albino rats | Author: Anonymous | Year: 1970 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Subchronic (90-day) toxicity studies with two organic tin compounds (Advastab 17 MOK 034 and Advastab 17 MOK 028) in albino rats | Author: Anonymous | Year: 1970 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 90-day dietary study in rats with compound TK 10 315 | Author: Anonymous | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: 90-day dietary study in rats with compound TK 10 315 | Author: Anonymous | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella/Mammalian-Microsome Mutagenicity Test with TK10 315 | Author: Anonymous | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella/Mammalian-Microsome Mutagenicity Test with TK10 315 | Author: Anonymous | Year: 1979 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Evaluation of Irgastab 17 MOK in the Ames Salmonella/Microsome Plate Test | Author: Anonymous | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Evaluation of Irgastab 17 MOK in the Ames Salmonella/Microsome Plate Test | Author: Anonymous | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella/Mammalian-Microsome Mutagenicity Test. Test Material: TK 10 315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella/Mammalian-Microsome Mutagenicity Test. Test Material: TK 10 315 (Irgastab 17 MOK) | Author: Anonymous | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Gene mutation test at the TK-locus of L5178Y cells with Dioctyltin bis(2-ethylhexylmercaptoacetate) | Author: Steenwinkel MJST and Van der Horst-Groeneveld JML. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Gene mutation test at the TK-locus of L5178Y cells with Dioctyltin bis(2-ethylhexylmercaptoacetate) | Author: Steenwinkel MJST and Van der Horst-Groeneveld JML. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal developmental toxicity study of CD54-0028 administered orally in Swiss albino mice | Author: Raghunatha Reddy KR | Year: 2014 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal developmental toxicity study of CD54-0028 administered orally in Swiss albino mice | Author: Raghunatha Reddy KR | Year: 2014 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal developmental toxicity study of CD54-0028 administered orally in New Zealand white rabbits | Author: Raghunatha Reddy KR | Year: 2014 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal developmental toxicity study of CD54-0028 administered orally in New Zealand white rabbits | Author: Raghunatha Reddy KR | Year: 2014 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Two-generation reproduction toxicity study of MOTTG/DOTTG in rats by administration in the diet | Author: Anonymous | Year: 1997 | Guideline: 416 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Two-generation reproduction toxicity study of MOTTG/DOTTG in rats by administration in the diet | Author: Anonymous | Year: 1997 | Guideline: 416 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Carcinogenicity | Waiver | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: 8-Oxa-3,5-dithia-4-stannatetradecanoic acid 10-ethyl-4,4-dioctyl-7-oxo-, 2-ethylhexyl ester [Dioctyltin bis(2-ethylhexylmercaptoacetate), CAS No. 15571-58-1]: 96-Hour acute toxicity in zebra-fish with DOT(EHMA) (semi-static). | Author: Migchielsen M.H.J. | Year: 2004 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: TNO/NOTOX report amendment. 8-Oxa-3,5-dithia-4-stannatetradecanoic acid 10-ethyl-4,4-dioctyl-7-oxo-, 2-ethylhexyl ester [Dioctyltin bis(2-ethylhexylmercaptoacetate), CAS No. 15571-58-1]: 96-Hour acute toxicity study in zebra-fish with DOT(EHMA) | Author: Migchielsen M.H.J. and de Haan H.P.M. | Year: 2005 | Guideline: 203 | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Immobilisation Test of MOTE on Daphnia magna under static conditions | Author: T.S. Sadananda | Year: 2016 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute Immobilisation Test of MOTE on Daphnia magna under static conditions | Author: T.S. Sadananda | Year: 2016 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: 8-Oxa-3,5-dithia-4-stannatetradecanoic acid 10-ethyl-4,4-dioctyl-7-oxo-, 2-ethylhexyl ester [Dioctyltin bis(2-ethylhexylmercaptoacetate), CAS. No. 15571-58-1]: Daphnia magna reproduction test (semi-static) | Author: de Roode D.F. and H.P.M. de Haan. 2004 | Year: 2004 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Report on the test for inhibitory concentration on aerobic bacteria of Irgastab 17 MOK-A | Author: Baumann W | Year: 1992 | Guideline: Directive 87 / 302 / EEC, part C, p. 118 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Report on the test for inhibitory concentration on aerobic bacteria of Irgastab 17 MOK-A | Author: Baumann W | Year: 1992 | Guideline: Directive 87 / 302 / EEC, part C, p. 118 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Determination of the Biodegradability of TZ 03499 in the Manometric Respirometry Test | Author: Beimborn | Year: 2000 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Determination of the Biodegradability of TZ 03499 in the Manometric Respirometry Test | Author: Beimborn | Year: 2000 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Report on the test for ready biodegradability in the Modified Sturm Test of Irgastab 17 MOK-A | Author: Baumann W. | Year: 1992 | Guideline: 84 / 449 / EEC C.5 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Report on the test for ready biodegradability in the Modified Sturm Test of Irgastab 17 MOK-A | Author: Baumann W. | Year: 1992 | Guideline: 84 / 449 / EEC C.5 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Report on the test for ready biodegradability in the Modified Sturm Test of Irgastab 17 MOK | Author: Baumann W. | Year: 1992 | Guideline: 84 / 449 / EEC C.5 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Report on the test for ready biodegradability in the Modified Sturm Test of Irgastab 17 MOK | Author: Baumann W. | Year: 1992 | Guideline: 84 / 449 / EEC C.5 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: DOTE- Hydrolysis as a Function of pH value | Author: Dr. Hans Naẞhan | Year: 2017 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: DOTE- Hydrolysis as a Function of pH value | Author: Dr. Hans Naẞhan | Year: 2017 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Balthussen | Year: 2010 | Guideline: A.9. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of physico-chemical properties of dioctylin bis(2-ethylhexylmercaptroacetate) | Author: Balthussen | Year: 2010 | Guideline: A.9. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Micronucleus test on ZK 30 434 | Author: Hossack D.J.N, Richold M. and Richardson J.C. | Year: 1980 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: -. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Micronucleus test on ZK 30 434 | Author: Hossack D.J.N Richold M. and Richardson J.C. | Year: 1980 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: -. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Acute Immobilisation Test of DOTE on Daphnia magna under static conditions | Author: T.S. Sadananda | Year: 2016 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Acute Immobilisation Test of DOTE on Daphnia magna under static conditions | Author: T.S. Sadananda | Year: 2016 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |