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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Certificate of Analysis | Author: Sigma Aldrich | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Physical Properties of Organic Chemicals | Author: Howard P. H., Meylan W. M. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Boatman R. in Patty's Toxicology Fifth Edition. Glycols and Glycol Ethers. | Author: Bingham E., Cohrssen B. and Powell C. H. (Eds.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Patty's Toxicology Fifth Edition. Glycols and Glycol Ethers. | Author: Bingham E., Cohrssen B. and Powell C. H. (Eds.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Density and Vapor Pressure Data for Propylene glycol monopropyl ether and Dipropylene glycol n-propyl ether | Author: The Dow Chemical Company | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Boatman R. in Patty's Toxicology Fifth Edition. Glycols and Glycol Ethers. | Author: Bingham E., Cohrssen B. and Powell C. H. (Eds.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Density and Vapor Pressure Data for Propylene glycol monopropyl ether and Dipropylene glycol n-propyl ether | Author: The Dow Chemical Company | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Boatman R. in Patty's Toxicology Fifth Edition. Glycols and Glycol Ethers. | Author: Bingham E., Cohrssen B. and Powell C. H. (Eds.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Density and Vapor Pressure Data for Propylene glycol monopropyl ether and Dipropylene glycol n-propyl ether | Author: The Dow Chemical Company | Year: 1993 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Temperature dependence of industrial propylene glycol alkyl ether/water mixtures | Author: P. Bauduin et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Mutual Solubility and Lower Critical Solution Temperature for Water + Glycol Ether Systems | Author: Christensen S. et. al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: An examination of the physical properties fate ecotoxicity and potential environmental risks for a series of propylene glycol ethers | Author: Staples C. A., Davis J. W. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Handbook of Physical Properties of Organic Chemicals | Author: Howard P. H., Meylan W. M. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: SRC - KOW for Microsoft Windows v1.54b Octanol/water partition coefficient estimating software. | Author: Meylan W | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Industrial Solvents Handbook | Author: Flick E. W. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: DIPPR Project 801 | Author: No author provided | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Density and Viscosity of Mixtures of Alkoxypropanols with Ethanol at T = (298.15 308.15 and 318.15) K | Author: Su-Chen Ku et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: DIPPR - Reference: (3031) Shebeko Yu.N., Ivanov A.V., Dmitrieva T.M., 'Methods of Calculation of Lower Concentration Limits of Combustion of Gases and Vapors in Air', Sov. Chem. Ind., 15 3, 311-314 (1983) | Author: Design Institute for Physical Properties | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: DIPPR - Reference: (3172) Danner R.P. Daubert T.E. 'Manual for Predicting Chemical Process Design Data', AIChE, New York, NY (1990) | Author: Design Institute for Physical Properties | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Boatman R. in Patty's Toxicology Fifth Edition. Glycols and Glycol Ethers. | Author: Bingham E., Cohrssen B. and Powell C. H. (Eds.) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Reactive Chemicals Analysis | Author: The Dow Chemical Company | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Reactive Chemicals Hazard Data | Author: The Dow Chemical Company | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Propylene Glycol Propyl Ether: Acute Toxicological Properties | Author: The Dow Chemical Company | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: PROPASOL Solvent P Acute Toxicity and Primary Irritancy Studies | Author: The Dow Chemical Company | Year: 1986 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Results Of range Finding Toxicological Tests On Propylene Glycol-n-Propyl Ether | Author: The Dow Chemical Company | Year: 1959 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: PROPASOL Solvent P Acute Toxicity and Primary Irritancy Studies | Author: The Dow Chemical Company | Year: 1986 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Propylene Glycol Propyl Ether: Acute Toxicological Properties | Author: The Dow Chemical Company | Year: 1984 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Results Of Range Finding Toxicological Tests On Propylene Glycol-n-Propyl Ether | Author: The Dow Chemical Company | Year: 1959 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: DOWANOL™ PNP: LOCAL LYMPH NODE ASSAY IN CBA/J MICE | Author: The Dow Chemical Company | Year: 2009 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Test On Propylene Glycol n-Propyl Ether (DOWANOL PnP): Salmonella-Escherichia Coli/Mammalian-Microsome Reverse Mutation | Author: The Dow Chemical Company | Year: 1996 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Evaluation Of Propylene Glycol n-Propyl Ether (DOWANOL PnP) In An In Vitro Chromosomal Aberration Assay Utilizing Rat Lymphocytes | Author: The Dow Chemical Company | Year: 1996 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Evaluation Of Propylene Glycol n-Propyl Ether (DOWANOL PnP) In The Chinese Hamster Ovary Cell/ Hypoxanthine-Guanine-Phosphoribosyl Transferase (CHO/HGPRT) Forward Mutation Assay | Author: The Dow Chemical Company | Year: 1996 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: PROPASOL Solvent P Acute Toxicity and Primary Irritancy Studies | Author: The Dow Chemical Company | Year: 1986 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Miscellaneous Toxicity Studies | Author: The Dow Chemical Company | Year: 1977 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Propylene Glycol Propyl Ether: Acute Toxicological Properties | Author: The Dow Chemical Company | Year: 1984 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Results Of Range Finding Toxicological Tests On Propylene Glycol-n-Propyl Ether | Author: The Dow Chemical Company | Year: 1959 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: PROPASOL Solvent P | Author: The Dow Chemical Company | Year: 1986 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Miscellaneous Toxicity Studies | Author: The Dow Chemical Company | Year: 1977 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Propylene Glycol Propyl Ether: An Acute Vapor Inhalation Study With Rats | Author: The Dow Chemical Company | Year: 1985 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Propylene Glycol Propyl Ether: Acute Toxicological Properties | Author: The Dow Chemical Company | Year: 1984 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: PROPASOL Solvent P | Author: The Dow Chemical Company | Year: 1986 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Miscellaneous Toxicity Studies | Author: The Dow Chemical Company | Year: 1977 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: PROPASOL Solvent P: Additional Two-Week Vapor Exposure Study with Male Fischer 344 and Sprague-Dawley Rats | Author: The Dow Chemical Company | Year: 1989 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: PROPASOL Solvent P: Nine-Day Vapor Exposure Study on Rats | Author: The Dow Chemical Company | Year: 1987 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: PROPASOL Solvent P: Fourteen-Week Vapor Inhalation Study with Fischer 344 and Sprague-Dawley Rats | Author: The Dow Chemical Company | Year: 1990 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: PROPASOL Solvent P: Nine-Day Vapor Exposure Study on Male Rats Rabbits and Guinea Pigs with Particular Reference to Ocular Effects | Author: The Dow Chemical Company | Year: 1987 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Developmental Toxicity Study of PROPASOL Solvent P Vapor in New Zealand White Rabbits | Author: The Dow Chemical Company | Year: 1992 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Developmental Toxicity Study of PROPASOL Solvent P Vapor in CD (Sprague-Dawley) Rats | Author: The Dow Chemical Company | Year: 1992 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Propylene glycol monomethyl ether: Two-generation inhalation reproduction study in Sprague-Dawley rats. | Author: The Dow Chemical Company | Year: 1997 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 107-98-2 | EC 203-539-1 | 1-methoxypropan-2-ol) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Assessment of adult and neonatal reprouctive parameters in Sprague-Dawley rats exposed to propylene glycol monomehtyl ehter vapors for two generations. | Author: Carney E.W. et al. | Year: 1999 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 107-98-2 | EC 203-539-1 | 1-methoxypropan-2-ol) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: DOWANOL PnP: Acute Toxicity To Rainbow Trout (Oncorhynchus mykiss Walbaum) And Daphnia (Daphnia magna Straus) | Author: The Dow Chemical Company | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: DOWANOL PnP: Acute Toxicity To Rainbow Trout (Oncorhynchus mykiss Walbaum) And Daphnid (Daphnia magna Straus) | Author: The Dow Chemical Company | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: DOWANOL PnP: Acute Toxicity To The Green Algae Selenastrum capricornutum Printz | Author: The Dow Chemical Company | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Aerobic Biodegradation Of Propylene Glycol N-Propyl Ether (DOWANOL PnP) In The DOC Die-Away Test OECD Method 301 A | Author: The Dow Chemical Company | Year: 1995 | Guideline: 301A | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Dipropylene Glycol N-Propyl Ether (DPnP): Reproduction/Developmental Toxicity Screening Test in CRL:CD(SD) Rats | Author: The Dow Chemical Company | Year: 2007 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 29911-27-1 | EC 249-949-4 | 1-(1-methyl-2-propoxyethoxy)propan-2-ol) |
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| Robust Studies Summaries | Robust Study Summary -- Title: Robust Studies Summaries package for all studies (>1000 tpa). | - |
| Chemical Safety Report | Title: Chemical Safety Report. | - |