You are here: Home> South Korea>K-REACH>CAS 1873-88-7> CAS 1873-88-7 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: 1,1,1,3,5,5,5-Heptamethyltrisiloxane: Acute Toxicity to Daphnia magna in a 48-Hour Immobilization Test | Author: Harlan Laboratories Ltd | Year: 2011 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: 1,1,1,3,5,5,5-Heptamethyltrisiloxane: Acute Toxicity to Daphnia magna in a 48-Hour Immobilization Test | Author: Harlan Laboratories Ltd | Year: 2011 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: 1,1,1,3,5,5,5-Heptamethyltrisiloxane: Acute Toxicity to Zebra Fish (Brachydanio rerio) in a 96-Hour Test | Author: Harlan Laboratories Ltd. | Year: 2011 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: 1,1,1,3,5,5,5-Heptamethyltrisiloxane: Acute Toxicity to Zebra Fish (Brachydanio rerio) in a 96-Hour Test | Author: Harlan Laboratories Ltd. | Year: 2011 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): Characterisation and determination of melting point/melting range and boiling point | Author: O'Connor B J, Woolley S M | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): Characterisation and determination of melting point/melting range and boiling point | Author: O'Connor B J, Woolley S M | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): Characterisation and determination of melting point/melting range and boiling point | Author: O'Connor B J, Woolley S M | Year: 2008 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella typhimurium and Escherichia coli Reverse Mutation Assay with 1,1,1,3,5,5,5-Heptamethyltrisiloxane | Author: Sokolowski, A. | Year: 2008 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella typhimurium and Escherichia coli Reverse Mutation Assay with 1,1,1,3,5,5,5-Heptamethyltrisiloxane | Author: Sokolowski, A. | Year: 2008 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: 1,1,1,3,5,5,5- Heptamethyltrisiloxane: Assessment of Ready Biodegradability | Year: 2010 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: 1,1,1,3,5,5,5- Heptamethyltrisiloxane: Assessment of Ready Biodegradability | Year: 2010 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): determination of vapour pressure | Author: Tremain S P | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): determination of vapour pressure | Author: Tremain S P | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity in the rat (up and down procedure) | Author: RCC | Year: 2008 | Guideline: 425 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity in the rat (up and down procedure) | Author: RCC | Year: 2008 | Guideline: 425 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of the water solubility of 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7) | Author: Tobler N | Year: 2010 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of the water solubility of 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7) | Author: Tobler N | Year: 2010 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Wacker Silicone Fluid AK 1: Contact hypersensitivity in albino guinea pigs maximization test | Author: RCC | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Wacker Silicone Fluid AK 1: Contact hypersensitivity in albino guinea pigs maximization test | Author: RCC | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: In vitro percutaneous penetration of 14C-Decamethyltetrasiloxane (14C-L4) through human skin. | Author: Dow Corning Corporation | Year: 2006 | Guideline: 428 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Dermal absorption | Right to refer to study -- Title: In vitro percutaneous penetration of 14C-Decamethyltetrasiloxane (14C-L4) through human skin. | Author: Dow Corning Corporation | Year: 2006 | Guideline: 428 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Model Reporting Format: Prediction of density based on structural contributions Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Model Reporting Format: Prediction of density based on structural contributions Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 1,1,1,3,5,5,5-heptamethyltrisiloxane (CAS No. 1873-88-7): Characterisation and determination of melting point/melting range and boiling point | Author: O'Connor B J, Woolley S M | Year: 2008 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: WACKER SILICONE FLUID AK 1: Primary skin irritation study in rabbits (4-hour semi-occlusive application) | Author: RCC Ltd | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: WACKER SILICONE FLUID AK 1: Primary skin irritation study in rabbits (4-hour semi-occlusive application) | Author: RCC Ltd | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute Skin Irritation Test (Patch Test) of Siloxan HSI2 in Rabbits | Author: Wacker | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute Skin Irritation Test (Patch Test) of Siloxan HSI2 in Rabbits | Author: Wacker | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Trimethoxysilane - Acute Toxicity to Daphnids (Daphnia magna) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Trimethoxysilane - Acute Toxicity to Daphnids (Daphnia magna) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Trimethoxysilane Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 2487-90-3 | EC 219-637-2 | Trimethoxysilane) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Trimethoxysilane Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 2487-90-3 | EC 219-637-2 | Trimethoxysilane) |
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| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |