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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: GESTIS - Substance database | Author: GESTIS | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Knovel Solvents - A Properties Database | Author: Wypych George | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Handbuch der gefährlichen Güter | Author: Günter Hommel | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Dampfdruck 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Dampfdruck 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: No information | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Dampfdruck von 1-Ethylpyrrolidon | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Dampfdruck von 1-Ethylpyrrolidon | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: FLÜSSIGDICHTE 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: FLÜSSIGDICHTE 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: FLUESSIGDICHTE N-Ethylpyrrolidon | Author: BASF AG | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: FLUESSIGDICHTE N-Ethylpyrrolidon | Author: BASF AG | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruck von 1-Ethylpyrrolidon | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruck von 1-Ethylpyrrolidon | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physico-chemical properties of "N-Ethyl-2-pyrroiidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physico-chemical properties of "N-Ethyl-2-pyrroiidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruck 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruck 1-Ethyl-2-pyrrolidon | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Final Report Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Final Report Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Guideline: 115 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Physico-chemical properties of "N-Ethyl-2-pyrrolidon" | Author: BASF AG | Year: 2005 | Guideline: 115 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Industrial Solvents Handbook (5th Edition) | Author: Flick E.W | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Flammpunkt nach DIN EN 22719 Zündtemperatur | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Flammpunkt nach DIN EN 22719 Zündtemperatur | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Dampfdruck Explosionspunkte Flammpunkt nach DIN EN 22719 Zündtemperatur Dynamische Differenzkalorimetrie (DSC | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Dampfdruck Explosionspunkte Flammpunkt nach DIN EN 22719 Zündtemperatur Dynamische Differenzkalorimetrie (DSC | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Dampfdruck Explosionspunkte Flammpunkt nach DIN EN 22719 Zündtemperatur Dynamische Differenzkalorimetrie (DSC | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Dampfdruck Explosionspunkte Flammpunkt nach DIN EN 22719 Zündtemperatur Dynamische Differenzkalorimetrie (DSC | Author: BASF AG | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Flammpunkt nach DIN EN 22719 Zündtemperatur | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Flammpunkt nach DIN EN 22719 Zündtemperatur | Author: BASF AG | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: SRC EpiSuite v3.20 | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: SRC EpiSuite v3.20 | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Determination of the Biodegradability in the DOC Die-Away Test | Author: BASF SE | Year: 2005 | Guideline: 301A | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Determination of the Biodegradability in the DOC Die-Away Test | Author: BASF SE | Year: 2005 | Guideline: 301A | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: EPI Suite calculation for CAS 2687-91-4 | Author: BASF SE | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: EPI Suite calculation for CAS 2687-91-4 | Author: BASF SE | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Estimation of the log Pow | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Estimation of the log Pow | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: N-ethyl-2-pyrrolidon acute fish toxicity test | Author: BASF SE | Year: 1998 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: N-ethyl-2-pyrrolidon acute fish toxicity test | Author: BASF SE | Year: 1998 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: N-ethyl-2-pyrrolidon acute Daphnia toxicity test | Author: BASF SE | Year: 2005 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: N-ethyl-2-pyrrolidon acute Daphnia toxicity test | Author: BASF SE | Year: 2005 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: N-ethyl-2-pyrrolidon Determination of the inhibitory effect on the cell multiplication of unicellular green algae | Author: BASF SE | Year: 2005 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: N-ethyl-2-pyrrolidon Determination of the inhibitory effect on the cell multiplication of unicellular green algae | Author: BASF SE | Year: 2005 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: N-ethylpyrrolidon respiration inhibition test | Author: BASF SE | Year: 1990 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: N-ethylpyrrolidon respiration inhibition test | Author: BASF SE | Year: 1990 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Report on the study of the acute oral toxicity of N-ethyl pyrrolidone in rats. English translation of the original German report (Oct. 10 2005). | Author: BASF AG | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report on the study of the acute oral toxicity of N-ethyl pyrrolidone in rats. English translation of the original German report (Oct. 10 2005). | Author: BASF AG | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidon - Acute inhalation toxicity study in Wistar rats; 4-hour exposure to a mixture of liquid aerosol and vapor. | Author: BASF AG | Year: 2005 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: N-Ethyl-2-pyrrolidon - Acute inhalation toxicity study in Wistar rats; 4-hour exposure to a mixture of liquid aerosol and vapor. | Author: BASF AG | Year: 2005 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidon - Acute dermal toxicity study in rats. | Author: BASF AG | Year: 2005 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: N-Ethyl-2-pyrrolidon - Acute dermal toxicity study in rats. | Author: BASF AG | Year: 2005 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Report on the acute dermal irritation/corrosivity to the intact dorsal skin of the white rabbit based on OECD. | Author: BASF AG | Year: 1986 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Report on the acute dermal irritation/corrosivity to the intact dorsal skin of the white rabbit based on OECD. | Author: BASF AG | Year: 1986 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Report on the acute irritation to the eye of the white rabbit based on OECD. | Author: BASF AG | Year: 1986 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report on the acute irritation to the eye of the white rabbit based on OECD. | Author: BASF AG | Year: 1986 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidon - Acute eye irritation in rabbits. | Author: BASF AG | Year: 2005 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: N-Ethyl-2-pyrrolidon - Acute eye irritation in rabbits. | Author: BASF AG | Year: 2005 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidon - Murine Local Lymph Node Assay (LLNA). | Author: BASF AG | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: N-Ethyl-2-pyrrolidon - Murine Local Lymph Node Assay (LLNA). | Author: BASF AG | Year: 2005 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Amendment No. 1 to the report. | Author: BASF AG | Year: 2006 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 4-Week repeated dose oral toxicity study of N-ethyl-2-pyrrolidone in Sprague Dawley rats | Author: A.M. Saillenfait et al. | Year: 2016 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: N-Ethyl-2-pyrrolidone in vitro gene mutation test in CHO cells (HPRT locus assay) | Author: BASF SE | Year: 2008 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: N-Ethyl-2-pyrrolidone in vitro gene mutation test in CHO cells (HPRT locus assay) | Author: BASF SE | Year: 2008 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Study of N-Ethyl-2-pyrrolidon in the Ames Salmonella/Mammalian-Microsome Mutagenicity Test and Escherichia coli/Mammalian-Microsome Reverse Mutation Assay (Standard Plate Test and Preincubation Test). | Author: BASF AG | Year: 1998 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Study of N-Ethyl-2-pyrrolidon in the Ames Salmonella/Mammalian-Microsome Mutagenicity Test and Escherichia coli/Mammalian-Microsome Reverse Mutation Assay (Standard Plate Test and Preincubation Test). | Author: BASF AG | Year: 1998 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and elimination of N-ethyl-2-pyrrolidone (NEP) in human males after oral dosage | Author: H. M. Koch et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |