You are here: Home> Taiwan>TW-REACH>CAS 4098-71-9> CAS 4098-71-9 | Data Package 100 - 1000 t/a (Affiliates of Evonik)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Bayer isophorone diisocyanate exposure questionnaire (unpublished) | Author: Bayer MaterialScience AG | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Bayer isophorone diisocyanate exposure questionnaire (unpublished) | Author: Bayer MaterialScience AG | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Degussa Corp. isophorone diisocyanate exposure questionnaire (unpublished) | Author: Degussa North America | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Degussa Corp. isophorone diisocyanate exposure questionnaire (unpublished) | Author: Degussa North America | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: TLVs and BEIs, Threshold Limit Values for Chemical Substances and Physical Agents, Biological Exposure Indices - isophorone diisocyanate | Author: ACGIH (American Conference of Governmental Industrial Hygienists) | Year: 2004 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Isophorondiamin, Isophorondiisocyanat / Auer Technikum | Author: Auergesellschaft | Year: 1988 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Isophorondiisocyanat, Merkblatt 917 / Handbuch der gefährlichen Güter | Author: Hommel G | Year: 1991 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Diisocyanate d'isophorone | Author: INRS (Institut national de recherche et de sécurité) Paris | Year: 1988 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Fiche toxicologique No 166: diisocyanate d'isophorone | Author: Morel C, Gendre M, Cavigneaux A and Protois JC | Year: 1982 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Isophorone diisocyanate / Hawley's condensed chemical dictionary, eleventh edition | Author: Sax NI and Lewis RJ sr (Eds.) | Year: 1987 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Isophorondiamin, Isophorondiisocyanat / Auer Technikum | Author: Auergesellschaft | Year: 1988 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Isophorondiamin, Isophorondiisocyanat / Auer Technikum | Author: Auergesellschaft | Year: 1988 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Vestamin IPD - Determination of the partition coefficient (log pow), shake flask method | Author: Hüls Infracor GmbH | Year: 1998 | Guideline: 107/117/123 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Vestamin IPD - Determination of the partition coefficient (log pow), shake flask method | Author: Hüls Infracor GmbH | Year: 1998 | Guideline: 107/117/123 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Isophorone diisocyanate: unpublished calculations using standard methods / equations | Author: Degussa AG | Year: 2006 | Guideline: 107/117/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Isophorone diisocyanate: unpublished calculations using standard methods / equations | Author: Degussa AG | Year: 2006 | Guideline: 107/117/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Löslichkeits- und Abbauverhalten von Isophorondiisocyanat (IPDI) in Wasser | Author: Infracor GmbH | Year: 2000 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Löslichkeits- und Abbauverhalten von Isophorondiisocyanat (IPDI) in Wasser | Author: Infracor GmbH | Year: 2000 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Bestimmung von physikalisch-chemischen Stoffdaten - Dampfdruck | Author: Bayer AG | Year: 1994 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Bestimmung von physikalisch-chemischen Stoffdaten - Dampfdruck | Author: Bayer AG | Year: 1994 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of the flash point of Vestanat IPDI | Author: AQura GmbH | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of the flash point of Vestanat IPDI | Author: AQura GmbH | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of the explosion properties of Vestanat IPDI | Author: AQura GmbH | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of the explosion properties of Vestanat IPDI | Author: AQura GmbH | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Isophorondiamin, Isophorondiisocyanat / Auer Technikum | Author: Auergesellschaft | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Isophorondiisocyanat, Merkblatt 917 / Handbuch der gefährlichen Güter | Author: Hommel G | Year: 1991 | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Diisocyanate d'isophorone | Author: INRS (Institut national de recherche et de sécurité) Paris | Year: 1988 | Adequacy: weight of evidence. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Fiche toxicologique No 166: diisocyanate d'isophorone | Author: Morel C, Gendre M, Cavigneaux A and Protois JC | Year: 1982 | Adequacy: weight of evidence. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Determination of the viscosity of Vestanat IPDI | Author: Fieseler A | Year: 2012 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Determination of the viscosity of Vestanat IPDI | Author: Fieseler A | Year: 2012 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction. | - |
| Phys-Chem | Metal Corrosion | Waiver | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Akute Toxizitätsprüfung von3-Isocyanatomethyl-3.5.5-trimethylcyclohexyl isocyanat nach oraler Applikation an der Ratte | Author: IBR International Bio-Research | Year: 1976 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Akute Toxizitätsprüfung von3-Isocyanatomethyl-3.5.5-trimethylcyclohexyl isocyanat nach oraler Applikation an der Ratte | Author: IBR International Bio-Research | Year: 1976 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Isophorondiisocyanat - study on acute inhalation toxicity in rats according to OECD 403 | Author: Bayer AG | Year: 1995 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Isophorondiisocyanat - study on acute inhalation toxicity in rats according to OECD 403 | Author: Bayer AG | Year: 1995 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: 3-Isocyanatomethyl-3.5.5-trimethylcyclohexylisocyanat - 4-hour acute inhalation toxicity study in rats | Author: RCC Research & Consulting Company Ltd. | Year: 1988 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: 3-Isocyanatomethyl-3.5.5-trimethylcyclohexylisocyanat - 4-hour acute inhalation toxicity study in rats | Author: RCC Research & Consulting Company Ltd. | Year: 1988 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Akute dermale Toxizität von Isophorondiisocyanat (IPDI) für Ratten | Author: Hüls AG | Year: 1985 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Akute dermale Toxizität von Isophorondiisocyanat (IPDI) für Ratten | Author: Hüls AG | Year: 1985 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Isophorondiisocyanat - study for skin irritation/corrosion in rabbits | Author: Krötlinger F | Year: 1994 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Isophorondiisocyanat - study for skin irritation/corrosion in rabbits | Author: Krötlinger F | Year: 1994 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: The evaluation of isophorone diisocyanate for mucous membrane irritation in rabbits | Author: Mobay Chemical Corporation | Year: 1987 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: The evaluation of isophorone diisocyanate for mucous membrane irritation in rabbits | Author: Mobay Chemical Corporation | Year: 1987 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: 3-Isocyanatomethyl-3.5.5-trimethylcyclohexylisocyanat - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäß OECD Richtlinien) | Author: IBR (International Bio-Research), Huels AG | Year: 1983 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: 3-Isocyanatomethyl-3.5.5-trimethylcyclohexylisocyanat - Prüfung auf sensibilisierende Eigenschaften am Meerschweinchen nach B. Magnusson und A.M. Kligman (gemäß OECD Richtlinien) | Author: IBR (International Bio-Research), Huels AG | Year: 1983 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Determination of the mutagenicity of isophorone diisocyanate (IPDI) in the Ames Salmonella/mammalian microsomes mutagenicity test complying with Directive 84/449/EEC B.14 | Author: Hüls AG | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro gene mutation test in CHO cells (HPRT locus assay) with isophorone diisocyanate | Author: Schulz M and Landsiedel R | Year: 2007 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Determination of the mutagenicity of isophorone diisocyanate (IPDI) in the Ames Salmonella/mammalian microsomes mutagenicity test complying with Directive 84/449/EEC B.14 | Author: Hüls AG | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Determination of the mutagenicity of isophorone diisocyanate (IPDI) in the Ames Salmonella/mammalian microsomes mutagenicity test complying with Directive 84/449/EEC B.14 | Author: Hüls AG | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro gene mutation test in CHO cells (HPRT locus assay) with isophorone diisocyanate | Author: Schulz M and Landsiedel R | Year: 2007 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro gene mutation test in CHO cells (HPRT locus assay) with isophorone diisocyanate | Author: Schulz M and Landsiedel R | Year: 2007 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: IPDI chromosome aberrations in Chinese hamster ovary cells in vitro | Author: RTC (Research Toxicology Centre) | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: IPDI chromosome aberrations in Chinese hamster ovary cells in vitro | Author: RTC (Research Toxicology Centre) | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Isophorone diisocyanate - micronucleus test on the male mouse after inhalative exposure for 6 hours | Author: Herbold B | Year: 2006 | Guideline: 483 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Isophorone diisocyanate - micronucleus test on the male mouse after inhalative exposure for 6 hours | Author: Herbold B | Year: 2006 | Guideline: 483 | Klimisch score: 1 - Reliable without restriction. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Test chamber exposure of humans to 1,6-hexamethylene diisocyanate and isophorone diisocyanate | Author: Tinnerberg H, Skarping G, Dalene M and Hagmar L | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions. | - |
| Toxicological | Repeated dose toxicity: oral | Waiver | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Isophorondiisocyanate (IPDI) subacute inhalation toxicity on rats, study no. T0071598 | Author: Bayer AG | Year: 2003 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Isophorondiisocyanate (IPDI) subacute inhalation toxicity on rats, study no. T0071598 | Author: Bayer AG | Year: 2003 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Isophorone diisocyanate (IPDI) 90-day inhalation study with a 4-week recovery period in Wistar rats | Author: Pauluhn J | Year: 2008 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Isophorone diisocyanate (IPDI) 90-day inhalation study with a 4-week recovery period in Wistar rats | Author: Pauluhn J | Year: 2008 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: dermal | Waiver | - |
| Toxicological | Toxicity to reproduction | Waiver | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Isophorondiisocyanat (IPDI) - developmental toxicity study in rats after inhalation | Author: Klaus AM | Year: 2004 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Isophorondiisocyanat (IPDI) - developmental toxicity study in rats after inhalation | Author: Klaus AM | Year: 2004 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Bestimmung der Auswirkungen von Vestanat IPDI auf das Schwimmverhalten von Daphnia magna | Author: Hüls AG | Year: 1995 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Bestimmung der Auswirkungen von Vestanat IPDI auf das Schwimmverhalten von Daphnia magna | Author: Hüls AG | Year: 1995 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Bestimmung der biologischen Abbaubarkeit von Vestamin IPD im DOC-DIE Away test | Author: Hüls AG | Year: 1993 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Bestimmung der biologischen Abbaubarkeit von Vestamin IPD im DOC-DIE Away test | Author: Hüls AG | Year: 1993 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Bestimmung der akuten Wirkungen von Vestanat IPDI gegenüber Fischen (nach EG 92/69 C 1) | Author: Hüls AG | Year: 1996 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Bestimmung der akuten Wirkungen von Vestanat IPDI gegenüber Fischen (nach EG 92/69 C 1) | Author: Hüls AG | Year: 1996 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Decrease of NCO-content in water - Desmodur I | Author: Bayer AG | Year: 1999 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Decrease of NCO-content in water - Desmodur I | Author: Bayer AG | Year: 1999 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Löslichkeits- und Abbauverhalten von Isophorondiisocyanat (IPDI) in Wasser | Author: Infracor GmbH | Year: 2000 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Löslichkeits- und Abbauverhalten von Isophorondiisocyanat (IPDI) in Wasser | Author: Infracor GmbH | Year: 2000 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Investigation of the ecological properties of DESMODUR I Bakterientox., Algentox., Daphnientox., Fischtox., leichte biologische Abbaubarkeit | Author: Bayer AG | Year: 2000 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Isophorone diisocyanate: unpublished calculations using standard methods / equations | Author: Degussa AG | Year: 2006 | Guideline: 106 | Klimisch score: 2 - Reliable with restrictions | Adequacy: QSAR only. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Isophorone diisocyanate: unpublished calculations using standard methods / equations | Author: Degussa AG | Year: 2006 | Guideline: 106 | Klimisch score: 2 - Reliable with restrictions | Adequacy: QSAR only. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Waiver | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Toxicity to microorganisms | Waiver | - |