You are here: Home> Turkey>TR-REACH>CAS 67-64-1> CAS 67-64-1 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: Sax N. I. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals 2nd ed. | Author: Verschueren | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: Riddick J.A. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: The Merck Index | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: The Merck Index | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: Riddick J.A. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: Riddick J.A. et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Author: The Merck Index | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Acetone. Handbook of Chemistry and Physics 76th ed. | Author: Lide DR (ed.) | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: The Merck Index | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Partition coefficients and their uses | Author: Leo A. et al. | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: The partition of organic compounds between higher alcohols and water. | Author: Collander R. | Year: 1951 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Prediction of octanol-water partition coefficients using a group contribution solvation model | Author: Lin S.-T. et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals 2nd ed. | Author: Verschueren | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Acetone | Author: Sifniades S | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: No information | Author: Riddick JA et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Acetone | Author: Sifniades S. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: Riddick JA et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: No information | Author: CRC | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Kirk-Othmer encyclopedia of chemical technology 3rd ed | Author: Grayson M | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Acetone | Author: Sifniades S | Year: 1985 | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Acetone | Author: The Merck Index | Year: 1996 | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Organic Solvents - Physical properties and methods of purification. 4th Ed. | Author: Riddick JA et al. | Year: 1986 | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: The application of dissolved inorganic carbon measurements to the study of aerobic biodegradability | Author: Birch R; Fletcher R | Year: 1991 | Guideline: 301B | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: BOD and COD of some petrochemicals | Author: Bridié AL et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Acclimation and degradation of petrochemical wastewater components by methane fermentation | Author: Chou WL et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Brine shrimp bioassay and seawater BOD of petrochemicals | Author: Price KS et al. | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: An improved tool for measuring biodegradability | Author: Young RHF et al. | Year: 1968 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Anaerobic degradation of acetone by Desulfococcus biacutus spec. nov. | Author: Platen H et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Adsorption of organic pollutants on montmorillonite treated with amines | Author: Wolfe T et al. | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: The fate of toluene acetone and 12-dichloroethane in a laboratory-scale simulated landfill | Author: Sanin FD et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas) Vol. 1. | Author: Brooke LT et al. | Year: 1984 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates | Author: Johnson WW; Finley MT | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The acute toxicity of 78 chemicals and pesticide formulations against two brackish water organisms the bleak (Alburnus alburnus) and the harpacticoid Nitocra spinipes | Author: Linden E et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute lethality and sub-lethal effects of acetone ethanol and propylene glycol on the cardiovascular and respiratory systems of rainbow trout (Salmo gairdneri) | Author: Majewski HS | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Quantitative structure-activity relationship in fish toxicity studies. Part 1: Relationship for 50 industrial pollutants. | Author: Koenemann H | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Comparison of the susceptability of 22 fresh water species to 15 chemical compounds I. (sub)acute toxicity tests | Author: Slooff W et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Reproducibility of short-term and reproduction toxicity experiments with Daphnia magna and comparison of the sensitivity of Daphnia magna with Daphnia pulex and Daphnia cucullata in short term experiments | Author: Canton JH; Adema DMM | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Brine shrimp bioassay and seawater BOD of petrochemicals. | Author: Price KS et al. | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The acute and chronic toxicity of acetone dimethyl formamide and triethylene glycol to Daphnia magna (Straus) | Author: LeBlanc GA; Surprenant DC | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Ergebnisse der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna in einem weiterentwickelten standardisierten Testverfahren | Author: Bringmann G; Kühn R | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The acute toxicity of 78 chemicals and pesticide formulations against two brackish water organisms the bleak (Alburnus alburnus) and the harpacticoid Nitocra spinipes | Author: Linden E et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Comparison of the susceptability of 22 freshwater species to 15 chemical compounds. I. (Sub)acute toxicity tests. | Author: Slooff W et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Blaualgen (Microcystis aeroginosa) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G Kuehn R | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Toxicity of selected RCRA compounds to activated sludge microorganisms. | Author: Volskay VT et al. | Year: 1988 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: The toxicity of four organic solvents commonly used in the pharmaceutical industry to activated slugde | Author: Kilroy AC et al. | Year: 1992 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Comparative toxicites of selected industrial chemicals to microorganisms and other aquatic organisms | Author: Vaishnav DD et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Resistenz autochthoner Mirkoorganismen gegen grundwassergefährdende Chemikalien | Author: Dippell G et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Bakterien (Pseudomonas putida) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G et al. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: A database of chemical toxicity to environmental bacteria and its use in interspecies comparisons and correlations | Author: Blum DJW et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Comparison of the toxicity thresholds of water pollutants to bacteria algae and protozoa in the cell multiplication inhibition test | Author: Bringmann G et al. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Cytotoxicity of certain organic solvents and organophosphorus insecticides to the ciliated protozoan Paramecium caudatum | Author: Rajini PS et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Acute and chronic toxicity toward the bacteria Vibrio fischeri of organic narcotics and epoxides: Structural alerts for epoxide excess toxicity. | Author: Blaschke U et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Uptake of highly soluble gases in the epithelium of the conducting airways | Author: Schrikker ACM et al. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Urinary elimination of acetone in experimental and occupational exposure | Author: Pezzagno G et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicokinetic interactions between orally ingested chlorzoxazone and inhaled acetone or toluene in male volunteers | Author: Ernstgard L et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Exposure to acetone | Author: Wigaeus E et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The effects of physical effort on pulmonary uptake of selected organic compound vapours | Author: Jakubowski M; Wieczorek H | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Initial uptake of organic solvents in the human body by short-term exposure | Author: Teramoto K et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acute acetone intoxication in a pediatric patient | Author: Gamis AS; Wasserman GS | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition of acetone following acute acetone intoxication | Author: Ramu A et al. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Blood acetone concentration in "normal people" and in exposed workers 16 h after the end of the workshift | Author: Wang G et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Experimental studies for determining the MAC value of acetone. 2. Biological reactions in the "six-day exposure" to acetone | Author: Matsushita T et al. | Year: 1969 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Experimental studies for determining the MAC value of acetone. 1. Biological reactions in the "one-day exposure" to acetone (in Japanese) | Author: Matsushita T et al. | Year: 1969 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Neurobehavioural effects of short duration exposures to acetone and methyl ethyl ketone | Author: Dick RB et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Body burden profiles of single and mixed solvent exposures | Author: Brown WD et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acute experimental exposures to acetone and ethyl acetate | Author: Vangala RR et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Combined exposure to organic solvents: an experimental approach using acetone and ethyl acetate | Author: Seeber A et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acetone metabolism in humans during diabetic ketoacidosis | Author: Reichard GA et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acetone metabolism during diabetic ketoacidosis | Author: Owen OE et al. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Plasma acetone metabolism in the fasting human | Author: Reichard GA et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: A method for the estimation of acetone radioactivity and concentration in blood and urine | Author: Haff A Reichard G | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Patologia professionale da acetone: manifestazioni cliniche indagini negli ambienti di lavoro e ricerche fisiopathologiche (Occupational poisoning from acetone: clinical disturbances investigations in work rooms and physiological researches) (Italian) | Author: Parmeggiani L; Sassi C | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acetone excretion into urine of workers exposed to acetone in acetate fiber plants | Author: Satoh T et al. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Biological monitoring of workers exposed to acetone in acetate fiber plants | Author: Fujino A et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Relationship between acetone exposure concentration and health effects in acetate fiber plant workers | Author: Satoh T et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Species differences in upper respiratory tract deposition of acetone and ethanol vapors | Author: Morris JB et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Deposition of ethanol and acetone vapors in the upper respiratory tract of the rat | Author: Morris JB; Cavanagh DG | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and deposition of propanol and acetone vapors in the upper respiratory tract of the hamster | Author: Morris JB; Cavanagh DG | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Deposition of acetone vapor in the upper respiratory tract of the B6C3F1 mouse | Author: Morris JB | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Deposition of dibasic esters in the upper respiratory tract of the male and female Sprague-Dawley rat | Author: Morris JB et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Distribution and elimination of 2-[14C]-acetone in mice after inhalation exposure | Author: Wigaeus E et al. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Inhalation Developmental Toxicology Studies: Teratology Studies of Acetone in Mice and Rats | Author: National Toxicology Program (NTP) | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Inhalation pharmacokinetics based on gas uptake studies | Author: Hallier E et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Correlation between acetone-potentiated CCl4-induced liver injury and blood concentrations after inhalation or oral administration | Author: Charbonneau M et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Inhalation versus oral administrationof acetone: effect of the vehicle on the potentiation of CCl4-induced liver injury | Author: Charbonneau M et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetics of and CYP1A induction by pyridine and acetone in the rat: interactions and effects of the route of exposure | Author: Scholl HR Iba MM | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Isopropanol and acetone potentiation of carbon tetrachloride-induced hepatotoxicity: single versus repetitive pretreatments in rats. | Author: Plaa GL et al. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acetone and acetol inhibition of insulin-stimulated glucose oxidation in adipose tissue and isolated adipocytes | Author: Skutches CL et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Studies on the mechanism of induction of N-nitrosodimethylamine demethylase by fasting acetone and ethanol | Author: Miller KW Yang CS | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Serum acetone and liver acetone monooxygenase in pregnant rats fetuses and neonates: Reversible pretranslational reduction of cytochrome P450IIE1 (P450IIE1) during pregnancy | Author: Casazza JP et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Acetone levels in plasma and tissues: effect of pregnancy and fasting | Author: López-Soriano FJ; Argilés JM | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acetone potentiation of acute acetonitrile toxicity | Author: Freeman JJ; Hayes EP | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute toxicity and limits of solvent residue for sixteen organic solvents | Author: Kimura ET et al. | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A new protocol and criteria for quantitative determination of sensitization potencies of chemicals by guinea pig maximization test | Author: Nakamura A et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Identification of contact allergens: the mouse ear sensitization assay | Author: Descotes J | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals | Author: Zeiger E et al. | Year: 1992 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Acetone CAS Number: 67-64-1 Study type: Salmonella Study ID: 230717 | Author: National Toxicology Program (NTP) | Year: 1986 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. V: Results with 46 chemicals | Author: Loveday KS et al. | Year: 1990 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Acetone CAS Number: 67-64-1 Study type: chromosome aberrations Study ID: 197425 | Author: National Toxicology Program (NTP) | Year: 1986 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells. II. Test validation and interpretation | Author: Amacher DE et al. | Year: 1980 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |