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CAS 75-78-5 | Data Package 10 - 100 t/a

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Includes:

Study name Short Description Data Owner
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Repeated dose toxicity: oral Right to refer to study -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Dimethyldichlorsilan: Untersuchungen zur akuten oralen toxizität an männlichen und weiblichen Wistar-ratten | Author: Bayer AG | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: Dimethyldichlorsilan: Untersuchungen zur akuten oralen toxizität an männlichen und weiblichen Wistar-ratten | Author: Bayer AG | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Zündpunktbestimmung von M2 Silan | Author: Bimsner F | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Auto-ignition temperature Right to refer to study -- Title: Zündpunktbestimmung von M2 Silan | Author: Bimsner F | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Right to refer to study -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Hydrolysis Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer AG | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer AG | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Revised report The effect of dimethyldichlorosilane on the incidence of chromosome breaks and aberrations in rat bone marrow cells. | Author: Bioassay systems corporation | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Flash point Robust Study Summary -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Flash point Right to refer to study -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Dermal absorption Robust Study Summary -- Title: In vitro percutaneous absorption of 14C-dimethylsilanediol (14C-DMSD) applied in aqueous solution to human skin. | Author: Dow Corning Corporation | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Dermal absorption Right to refer to study -- Title: In vitro percutaneous absorption of 14C-dimethylsilanediol (14C-DMSD) applied in aqueous solution to human skin. | Author: Dow Corning Corporation | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol)
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Toxicological | Toxicity to reproduction Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol)
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Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | trimethoxy(methyl)silane)
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Eco-Tox | Toxicity to microorganisms Right to refer to study -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | Trimethoxy(methyl)silane)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol)
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Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol)
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Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol)
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Toxicological | Toxicity to reproduction Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol)
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Phys-Chem | Density Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions, version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Density Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions, version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution Waiver -
Phys-Chem | Oxidising properties Waiver -
Phys-Chem | Partition coefficient Waiver -
Toxicological | Repeated dose toxicity: inhalation Waiver -
Toxicological | Skin sensitisation Waiver -
Phys-Chem | Surface tension Waiver -
Toxicological | Toxicity to reproduction Waiver -
Phys-Chem | Water solubility Waiver -
Phys-Chem | Flammability Waiver -
Toxicological | Eye irritation Waiver -
Environmental | Adsorption/desorption Waiver -
Environmental | Biodegradation in water and sediment: simulation tests Waiver -
Phys-Chem | Explosive properties Waiver -
Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Houghton J S | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Hydrolysis Right to refer to study -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Houghton J S | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Phys-Chem | Flammability Robust Study Summary -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Flammability Right to refer to study -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Auto-ignition temperature Right to refer to study -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies. | Author: Bushy Run Research Center | Year: 1982 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies. | Author: Bushy Run Research Center | Year: 1982 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Hydrolysis Robust Study Summary -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane)
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Environmental | Hydrolysis Right to refer to study -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane)
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Dimethyldichlorsilan salmonella/mikrosomen test zur untersuchung auf punktmutagene wirkung | Author: Bayer | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Dimethyldichlorsilan salmonella/mikrosomen test zur untersuchung auf punktmutagene wirkung | Author: Bayer | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Right to refer to study -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: No information | Author: Weast RC | Year: 1969 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Phys-Chem | Appearance/physical state/colour Right to refer to study -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Appearance/physical state/colour Right to refer to study -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: Safety Data Sheet: Wacker Silane M2 version 2.10 | Author: Wacker-Chemie GmbH | Year: 2003 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Appearance/physical state/colour Right to refer to study -- Title: Safety Data Sheet: Wacker Silane M2 version 2.10 | Author: Wacker-Chemie GmbH | Year: 2003 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Explosive properties Robust Study Summary -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane)
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Phys-Chem | Explosive properties Right to refer to study -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane)
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Environmental | Hydrolysis Right to refer to study -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolysis Determination of Dimethoxydimethylsilane at Different pH Values | Author: Weissenfeld, M. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Hydrolysis Right to refer to study -- Title: Hydrolysis Determination of Dimethoxydimethylsilane at Different pH Values | Author: Weissenfeld, M. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol)
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Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol)
-
Environmental | Hydrolysis Robust Study Summary -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 675-62-7 | EC 211-623-4 | Dichloro(methyl)(3,3,3-trifluoropropyl)silane)
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Environmental | Hydrolysis Right to refer to study -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 675-62-7 | EC 211-623-4 | Dichloro(methyl)(3,3,3-trifluoropropyl)silane)
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Environmental | Hydrolysis Robust Study Summary -- Title: DOW Corning non-regulated technical report | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 80-10-4 | EC 201-251-0 | Dichloro(diphenyl)silane)
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Environmental | Hydrolysis Right to refer to study -- Title: DOW Corning non-regulated technical report | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 80-10-4 | EC 201-251-0 | Dichloro(diphenyl)silane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane)
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Environmental | Hydrolysis Right to refer to study -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-79-6 | EC 200-902-6 | Trichloro(methyl)silane )
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Environmental | Hydrolysis Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-79-6 | EC 200-902-6 | Trichloro(methyl)silane )
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Phys-Chem | Partition coefficient Robust Study Summary -- Title: Temperature Dependence of Air/Water, 1-Octanol/Air, 1-Octanol/Water Partitioning Coefficients of Dimethylsilanediol (DMSD) (CAS No: 1066-42-8) | Author: Shihe Xu | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol)
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Phys-Chem | Partition coefficient Right to refer to study -- Title: Temperature Dependence of Air/Water, 1-Octanol/Air, 1-Octanol/Water Partitioning Coefficients of Dimethylsilanediol (DMSD) (CAS No: 1066-42-8) | Author: Shihe Xu | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol)
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Phys-Chem | Vapour pressure Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: BEILSTEIN Database | Author: Phys Prop | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -