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CAS 78-92-2 | Data Package 10 - 100 t/a (Affiliates of MEK-SBA Consortium members)

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Includes:

Study name Short Description Data Owner
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (89th Ed) | Author: Lide DR | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: The Condensed Chemical Dictionary (10th Ed) | Author: Hawley G | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals, Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Boiling point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals, Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Occupational Health Guideline for sec-Butyl Alcohol | Author: Occupational Safety and Health Administration (OSHA) | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Edition) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Exploring QSAR - Hydrophobic Electronic and Steric Constants | Author: Hansch C, Leo A & Hoekman D | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Solubility Data Series | Author: Hefter GT | Year: 1984 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals. 3rd ed. | Author: Verschueren K | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. -
Phys-Chem | Flash point Robust Study Summary -- Title: Directory of Solvents | Author: P.Whim and P.G. Johnson | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Flash point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (11th Edition) | Author: Budavari S | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Fire Protection Guide to Hazardous Materials 13th Edition | Author: Spencer AB & Colonna GR | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Flammability Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: BOD and COD of Some Petrochemicals | Author: Bridié AL, Wolff CJM, & Winter M | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Ergebnisse der Untersuchung von 200 chemischen Verbindungen auf akute Fischtoxizität mit den Goldenorfentest | Author: Juhnke I. and Lüdemann D. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Determination of Acute toxicity to Fish of Shell Chemicals.I. | Author: Bridié AL, Winter M & Wolff CJM | Year: 1973 | Klimisch score: 3 - Not reliable | Adequacy: disregarded due to major methodological deficiencies | GLP: N. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Determination of Acute toxicity to Fish of Shell Chemicals.I. | Author: Bridié AL, Winter M & Wolff CJM | Year: 1973 | Klimisch score: 3 - Not reliable | Adequacy: disregarded due to major methodological deficiencies | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Befunde der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna | Author: Bringmann G and Kühn R | Year: 1977 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Comparison of the Toxicity Thresholds of Water Pollutants to Bacteria Algae and Protozoa in the Cell Multiplication Inhibition Test | Author: Bringmann G & Kühn R | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. II. Bakterienfressende Ciliaten | Author: Bringmann G. and Kühn R. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. III. Saprozoische Flagellaten | Author: Bringmann G., Kühn R., and Winter A. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Bakterien (Pseudomonas putida) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G and Kühn R | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Comparison of the Toxicity Thresholds of Water Pollutants to Bacteria Algae and Protozoa in the Cell Multiplication Inhibition Test | Author: Bringmann G & Kühn R | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. I. Bakterienfressende Flagellaten (Modellorganismus: Entosiphon sulcatum Stein) | Author: Bringmann G. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of 2-butanol and its metabolites in the rat | Author: Dietz FK, Rodriguez-Giaxola M, Traiger GJ et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: RANGE FINDING TOXICITY DATA PT. V (5) | Author: Smyth HF, Carpenter CP, Weil CS et al. | Year: 1954 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Robust Study Summary -- Title: Eye Irritation: Reference chemicals data bank (second edition) | Author: ECETOC | Year: 1998 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Toxicological | Eye irritation Robust Study Summary -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Right to refer to study -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: TOXICOLOGY OF INDUSTRIAL CHEMICALS (SOLVENTS): THE ACUTE ORAL AND PERCUTANEOUS TOXICITY SKIN AND EYE IRRITANCY AND SKIN SENSITIZING POTENTIAL OF SECONDARY BUTYL ALCOHOL (SBA; S1211) | Author: Shell Research Limited | Year: 1986 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: SKIN SENSITIZATION TEST IN GUINEA-PIGS (Maximization method of Magnusson B. and Kligman A.M.) | Author: Centre International de Toxicologie (CIT) | Year: 1997 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | Skin sensitisation Right to refer to study -- Title: SKIN SENSITIZATION TEST IN GUINEA-PIGS (Maximization method of Magnusson B. and Kligman A.M.) | Author: Centre International de Toxicologie (CIT) | Year: 1997 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Gene Mutation in yeast | Author: Microbiological Associates | Year: 1986 | Guideline: 480 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Gene Mutation in yeast | Author: Microbiological Associates | Year: 1986 | Guideline: 480 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Chrom. Aberration | Author: Shell Research Limited | Year: 1986 | Guideline: 473 | Klimisch score: 3 - Not reliable | Adequacy: key study | GLP: N. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Chrom. Aberration | Author: Shell Research Limited | Year: 1986 | Guideline: 473 | Klimisch score: 3 - Not reliable | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: BUTANOL SECONDAIRE TEST DE AMES "essai de mutation réverse sur Salmonella typhimurium" | Author: Sanofi Recherche | Year: 1989 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: BUTANOL SECONDAIRE TEST DE AMES "essai de mutation réverse sur Salmonella typhimurium" | Author: Sanofi Recherche | Year: 1989 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Bacterial Mutagenicity | Author: Shell Research Limited | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Genotoxicity Studies With Secondary Butyl Alcohol (SBA) Bacterial Mutagenicity | Author: Shell Research Limited | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Estimating the Acute Toxicity of Narcotic Industrial Chemicals to Fathead Minnows | Author: Veith GD, Call DJ & Brooke LT | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
Read-Across (CAS 67-63-0 | EC 200-661-7 | Propan-2-ol)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Befunde der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna | Author: Bringmann, G and Kühn R | Year: 1977 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
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Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Comparison of the Toxicity Thresholds of Water Pollutants to Bacteria Algae and Protozoa in the Cell Multiplication Inhibition Test | Author: Bringmann G & Kühn R | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
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Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Disposition and Pharmacokinetics of Isopropanol in F-344 Rats and B6C3F1 Mice. | Author: SLAUTER RW et al. | Year: 1994 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
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Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Characterization of the metabolites of methyl n-butyl ketone methyl iso-butyl ketone and methyl ethyl ketone in guinea pig serum and their clearance. | Author: DiVincenzo GD, Kaplan CJ, Dedinas J | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 78-93-3 | EC 201-159-0 | Butan-2-one)
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Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Kinetics of methyl ethyl ketone in man: absorption distribution and elimination in inhalation exposure. | Author: Liira J, Riihimaki V, Pfaffli P | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 78-93-3 | EC 201-159-0 | Butan-2-one)
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Toxicological | Acute toxicity: oral Robust Study Summary -- Title: FURTHER EXPERIENCE WITH THE RANGE FINDING TEST IN THE INDUSTRIAL TOXICOLOGY LABORATORY | Author: Smyth HF & Carpenter CP | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
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Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: FURTHER EXPERINCE WITH THE RANGE FINDING TEST IN THE INDUSTRIAL TOXICOLOGY LABORATORY | Author: Smyth HF & Carpenter CP | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
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Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Interspecies Comparisons of Skin Irritancy | Author: Nixon G, Tyson C & Wertz W | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
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Toxicological | Eye irritation Robust Study Summary -- Title: OCULAR IRRITATION STUDY IN THE RABBIT | Author: Plutnick RT | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
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Toxicological | Eye irritation Right to refer to study -- Title: OCULAR IRRITATION STUDY IN THE RABBIT | Author: Plutnick RT | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
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Toxicological | Skin sensitisation Robust Study Summary -- Title: Delayed Contact Hypersensitivity Study In Guinea Pig Of Isopropyl alcohol (TSIN-Y0370-01) | Author: Robert L. Doyle | Year: 1980 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
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Toxicological | Skin sensitisation Right to refer to study -- Title: Delayed Contact Hypersensitivity Study In Guinea Pig Of Isopropyl alcohol (TSIN-Y0370-01) | Author: Robert L. Doyle | Year: 1980 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity test on isopropanol in the CHO/HGPRT forward mutation assay with independent repeat | Author: Hazleton Laboratories America | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
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Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Mutagenicity test on isopropanol in the CHO/HGPRT forward mutation assay with independent repeat | Author: Hazleton Laboratories America | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Salmonella Mutagenicity Tests: V. Results from the Testing of 311 Chemicals | Author: Zeiger E, Anderson B, Haworth S, et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: The results of microbial mutation test for forty-three industrial chemicals. | Author: Shimizu H et al. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
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