You are here: Home> Turkey>TR-REACH>CAS 822-06-0> CAS 822-06-0 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: International Chemical Safety Cards (ICSC) | Author: NIOSH | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: International Chemical Safety Cards (ICSC) | Author: NIOSH | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Isocyanate | Author: Eisenmann K.-H. & Zenner K.-F. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Analytische Methoden zur Prüfung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat Sicherheitstechnische Kenndaten Gefahrenindex chemischer Stoffe | Author: Henschler D. Sorbe | Year: 1988 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Analytische Methoden zur Prüfung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat Sicherheitstechnische Kenndaten Gefahrenindex chemischer Stoffe | Author: Henschler D. Sorbe | Year: 1988 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: International Chemical Safety Cards (ICSC) | Author: NIOSH | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Isocyanate | Author: Eisenmann K.-H. & Zenner K.-F. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Isocyanate | Author: Eisenmann K.-H. & Zenner K.-F. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin | Author: Dr. Brunner | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 124-09-4 | EC 204-679-6 | 1,6-hexanediamine; hexane-1,6-diamine) |
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| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin | Author: Dr. Brunner | Year: 1988 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 124-09-4 | EC 204-679-6 | 1,6-hexanediamine; hexane-1,6-diamine) |
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| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow estimation of hexamethylene diisocyanate (CAS 822-06-0) | Author: Currenta GmbH & Co. OHG | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow estimation of hexamethylene diisocyanate (CAS 822-06-0) | Author: Currenta GmbH & Co. OHG | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test. | Author: Bayer AG | Year: 2000 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test. | Author: Bayer AG | Year: 2000 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Mikrobiologische Untersuchungen von Hexamethylendiisocyanat (Desmodur H) | Author: Bayer AG | Year: 1983 | Guideline: 302C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Mikrobiologische Untersuchungen von Hexamethylendiisocyanat (Desmodur H) | Author: Bayer AG | Year: 1983 | Guideline: 302C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Internal report: Investigation of the ecological properties of Desmodur H rein | Author: Bayer AG | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Internal report: Investigation of the ecological properties of Desmodur H rein | Author: Bayer AG | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with PDI | Author: Spoo-Klöppel M. | Year: 2016 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: Y. Read-Across (CAS 4538-42-5 | EC 807-040-5 | 15-Diisocyanatopentan) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with PDI | Author: Spoo-Klöppel M. | Year: 2016 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: weight of evidence | GLP: Y. Read-Across (CAS 4538-42-5 | EC 807-040-5 | 15-Diisocyanatopentan) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Internal report: Investigation of the ecological properties of Desmodur H rein | Author: Bayer AG | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Internal report: Investigation of the ecological properties of Desmodur H rein | Author: Bayer AG | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range finding tests on 1,6-hexamethylene diisocyanate (HMDI) Range-finding toxicity data: List VII | Author: Striegel JA and Carpenter CP Smyth Jr HF et al. | Year: 1964 1969 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range finding tests on 1,6-hexamethylene diisocyanate (HMDI) Range-finding toxicity data: List VII | Author: Striegel JA and Carpenter CP Smyth Jr HF et al. | Year: 1964 1969 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Desmodur H: Toxikologische Untersuchungen | Author: Kimmerle G et al. | Year: 1970 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Desmodur H: Toxikologische Untersuchungen | Author: Kimmerle G et al. | Year: 1970 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Cutaneous sensitization to some polyisocyanate prepolymers in guinea pigs | Author: Zissu D et al. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Development and validation of an alternative dermal sensitization test: The mouse ear swelling test (MEST) | Author: Gad SC et al. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Contact sensitivity by diisocyanates: Potencies and cross-reactivities | Author: Thorne PS et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Identification of chemical respiratory allergens dose-response relationships in the mouse IgE test | Author: Hilton J et al. | Year: 1995 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut | Author: Schmidt WM and Bomhard E | Year: 1983 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut | Author: Schmidt WM and Bomhard E | Year: 1983 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate Lack of mutagenic activity of 1,6-hexamethylene diisocyanate | Author: Wagner VO and Klug ML Wagner VO et al. | Year: 1998 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate Lack of mutagenic activity of 1,6-hexamethylene diisocyanate | Author: Wagner VO and Klug ML Wagner VO et al. | Year: 1998 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |