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CAS 822-06-0 - Data Package 100 - 1000 t/a + CSR

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Includes:

Product Name Short Description Data Owner
Melting point/freezing point Robust Study Summary - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 102; Klimisch score: 2 public
Melting point/freezing point Right to refer to study - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 102; Klimisch score: 2 public
Boiling point Robust Study Summary - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 103; Klimisch score: 2 public
Boiling point Right to refer to study - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 103; Klimisch score: 2 public
Density Robust Study Summary - Title: Isocyanate; Author: Eisenmann, K.-H. & Zenner, K.-F.; Year: 1977; Guideline: 109; Klimisch score: 2 public
Density Right to refer to study - Title: Isocyanate; Author: Eisenmann, K.-H. & Zenner, K.-F.; Year: 1977; Guideline: 109; Klimisch score: 2 Publication
Vapour pressure Robust Study Summary - Title: Analytische Methoden zur Pr³fung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat; Author: Henschler, D.; Year: 1988; Guideline: 104; Klimisch score: 2 public
Vapour pressure Right to refer to study - Title: Analytische Methoden zur Pr³fung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat; Author: Henschler, D.; Year: 1988; Guideline: 104; Klimisch score: 2 Publication
Water solubility Robust Study Summary - Title: waived public
Water solubility Right to refer to study - Title: waived public
Partition coefficient Robust Study Summary - Title: waived public
Partition coefficient Right to refer to study - Title: waived public
Partition coefficient Robust Study Summary - Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin; Author: Dr. Brunner; Year: 1988; Guideline: 107/117; Klimisch score: 2 Consortium
Partition coefficient Right to refer to study - Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin; Author: Dr. Brunner; Year: 1988; Guideline: 107/117; Klimisch score: 2 BASF AG
Particle size distribution (Granulometry) Robust Study Summary - Title: waived public
Particle size distribution (Granulometry) Right to refer to study - Title: waived public
Acute toxicity: oral Robust Study Summary - Title: Desmodur H: Toxikologische Untersuchungen; Author: Kimmerle G et al.; Year: 1970; Guideline: 420, 423, 425; Klimisch score: 2 Consortium
Acute toxicity: oral Right to refer to study - Title: Desmodur H: Toxikologische Untersuchungen; Author: Kimmerle G et al.; Year: 1970; Guideline: 420, 423, 425; Klimisch score: 2 Covestro Deutschland AG
Acute toxicity: oral Robust Study Summary - Title: Range-finding toxicity data: List VII; Author: Smyth Jr HF et al.; Year: 1969; Guideline: 420, 423, 425; Klimisch score: 2 public
Acute toxicity: oral Right to refer to study - Title: Range-finding toxicity data: List VII; Author: Smyth Jr HF et al.; Year: 1969; Guideline: 420, 423, 425; Klimisch score: 2 Publication
Skin irritation / corrosion Robust Study Summary - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf primõre Hautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 404; Klimisch score: 2 Consortium
Skin irritation / corrosion Right to refer to study - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf primõre Hautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 404; Klimisch score: 2 Covestro Deutschland AG
Skin sensitisation Robust Study Summary - Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut ; Author: Schmidt WM and Bomhard E; Year: 1983; Guideline: 406, 429; Klimisch score: 2 Consortium
Skin sensitisation Right to refer to study - Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut ; Author: Schmidt WM and Bomhard E; Year: 1983; Guideline: 406, 429; Klimisch score: 2 Covestro Deutschland AG
Genetic toxicity in vitro Robust Study Summary - Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate /Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Wagner VO and Klug ML / Wagner VO et al.; Year: 1998 / 2000; Guideline: 471; Klimisch score: 2 Consortium
Genetic toxicity in vitro Right to refer to study - Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate /Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Wagner VO and Klug ML / Wagner VO et al.; Year: 1998 / 2000; Guideline: 471; Klimisch score: 2 "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)"
Genetic toxicity in vitro Robust Study Summary - Title: In vitro mammalian cell gene mutation test with an independent repeat assay using vapor-phase exposure to 1,6-hexamethylene diisocyanate; Author: San RHC and Clarke JJ; Year: 1998; Guideline: 471; Klimisch score: 2 Consortium
Genetic toxicity in vitro Right to refer to study - Title: In vitro mammalian cell gene mutation test with an independent repeat assay using vapor-phase exposure to 1,6-hexamethylene diisocyanate; Author: San RHC and Clarke JJ; Year: 1998; Guideline: 471; Klimisch score: 2 "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)"
Short-term toxicity to fish Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 203; Klimisch score: 2 Consortium
Short-term toxicity to fish Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 203; Klimisch score: 2 Covestro Deutschland AG
Short-term toxicity to aquatic invertebrates Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 202; Klimisch score: 2 Consortium
Short-term toxicity to aquatic invertebrates Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 202; Klimisch score: 2 Covestro Deutschland AG
Biodegradation in water: screening tests Robust Study Summary - Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test.; Author: Bayer AG; Year: 2000; Guideline: 301C; Klimisch score: 1 Consortium
Biodegradation in water: screening tests Right to refer to study - Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test.; Author: Bayer AG; Year: 2000; Guideline: 301C; Klimisch score: 1 Covestro Deutschland AG
Flammability Robust Study Summary - Title: waived public
Flammability Right to refer to study - Title: waived public
Explosiveness Robust Study Summary - Title: waived public
Explosiveness Right to refer to study - Title: waived public
Oxidising properties Robust Study Summary - Title: waived public
Oxidising properties Right to refer to study - Title: waived public
Hydrolysis Robust Study Summary - Title: NCO-Abnahme in Wasser; Author: Bayer AG; Year: 1999; Guideline: 111; Klimisch score: 2 Consortium
Hydrolysis Right to refer to study - Title: NCO-Abnahme in Wasser; Author: Bayer AG; Year: 1999; Guideline: 111; Klimisch score: 2 Covestro Deutschland AG
Hydrolysis Robust Study Summary - Title: Zur Frage der Bedeutung der Stabilitõt von Diisocyanaten in Wasser bei hygienischer Normierung.; Author: Sopac, E.D. & Boltromejuk, L.P.; Year: 1974; Guideline: 111; Klimisch score: 2 public
Hydrolysis Right to refer to study - Title: Zur Frage der Bedeutung der Stabilitõt von Diisocyanaten in Wasser bei hygienischer Normierung.; Author: Sopac, E.D. & Boltromejuk, L.P.; Year: 1974; Guideline: 111; Klimisch score: 2 Publication
Acute toxicity: dermal Robust Study Summary - Title: Akute dermale Toxizitõt von Hexamethylendiisocyanat-1,6 (HDI) f³r Ratten; Author: M³rmann P; Year: 1985; Guideline: 402; Klimisch score: 2 Consortium
Acute toxicity: dermal Right to refer to study - Title: Akute dermale Toxizitõt von Hexamethylendiisocyanat-1,6 (HDI) f³r Ratten; Author: M³rmann P; Year: 1985; Guideline: 402; Klimisch score: 2 Evonik Resource Efficiency GmbH
Acute toxicity: inhalation Robust Study Summary - Title: 1,6-Hexamethylene diisocyanate (Desmodur H): Study on acute inhalation toxicity in rats according to OECD No. 403; Author: Pauluhn J; Year: 1997; Guideline: 403; Klimisch score: 1 Consortium
Acute toxicity: inhalation Right to refer to study - Title: 1,6-Hexamethylene diisocyanate (Desmodur H): Study on acute inhalation toxicity in rats according to OECD No. 403; Author: Pauluhn J; Year: 1997; Guideline: 403; Klimisch score: 1 Covestro Deutschland AG
Eye irritation Robust Study Summary - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf Schleimhautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 405; Klimisch score: 2 Consortium
Eye irritation Right to refer to study - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf Schleimhautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 405; Klimisch score: 2 Covestro Deutschland AG
Genetic toxicity in vitro Robust Study Summary - Title: waived public
Genetic toxicity in vitro Right to refer to study - Title: waived public
Repeated dose toxicity: oral Robust Study Summary - Title: waived public
Repeated dose toxicity: oral Right to refer to study - Title: waived public
Repeated dose toxicity: inhalation Robust Study Summary - Title: 90-day inhalation toxicity study with 1,6-hexamethylene diisocyanate (HDI) in rats; Author: Shiotsuka RN; Year: 1988; Guideline: 413; Klimisch score: 1 Consortium
Repeated dose toxicity: inhalation Right to refer to study - Title: 90-day inhalation toxicity study with 1,6-hexamethylene diisocyanate (HDI) in rats; Author: Shiotsuka RN; Year: 1988; Guideline: 413; Klimisch score: 1 "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)"
Toxicity to reproduction Robust Study Summary - Title: A combined repeated dose toxicity study with the reproduction/developmental toxicity screening test using 1,6-hexamethylene diisocyanate (HDI) in the Sprague-Dawley rat; Author: Astroff AB; Year: 1999; Guideline: 421, 422; Klimisch score: 1 Consortium
Toxicity to reproduction Right to refer to study - Title: A combined repeated dose toxicity study with the reproduction/developmental toxicity screening test using 1,6-hexamethylene diisocyanate (HDI) in the Sprague-Dawley rat; Author: Astroff AB; Year: 1999; Guideline: 421, 422; Klimisch score: 1 "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)"
Toxicity to aquatic algae and cyanobacteria Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 201; Klimisch score: 2 Consortium
Toxicity to aquatic algae and cyanobacteria Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 201; Klimisch score: 2 Covestro Deutschland AG
Dissociation constant Robust Study Summary - Title: waived public
Dissociation constant Right to refer to study - Title: waived public
Viscosity Robust Study Summary - Title: Determination of the viscosity of "1,6-Hexamethylendiisovyanat"; Author: BASF AG; Year: 2010; Guideline: 114; Klimisch score: 2 Consortium
Viscosity Right to refer to study - Title: Determination of the viscosity of "1,6-Hexamethylendiisovyanat"; Author: BASF AG; Year: 2010; Guideline: 114; Klimisch score: 2 BASF
Genetic toxicity in vivo Robust Study Summary - Title: Acute inhalation of hexamethylene diisocyanate for a mouse micronucleus assay / Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Gudi R and Krsmanovic L / Wagner VO et al.; Year: 1998 / 2000; Guideline: 486; Klimisch score: 2 Consortium
Genetic toxicity in vivo Right to refer to study - Title: Acute inhalation of hexamethylene diisocyanate for a mouse micronucleus assay / Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Gudi R and Krsmanovic L / Wagner VO et al.; Year: 1998 / 2000; Guideline: 486; Klimisch score: 2 "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)"
Long-term toxicity to fish Robust Study Summary - Title: waived public
Long-term toxicity to fish Right to refer to study - Title: waived public
Long-term toxicity to aquatic invertebrates Robust Study Summary - Title: waived public
Long-term toxicity to aquatic invertebrates Right to refer to study - Title: waived public
Toxicity to terrestrial plants Robust Study Summary - Title: waived public
Toxicity to terrestrial plants Right to refer to study - Title: waived public
Toxicity to soil macroorganisms except arthropods Robust Study Summary - Title: waived public
Toxicity to soil macroorganisms except arthropods Right to refer to study - Title: waived public
Toxicity to microorganisms Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 209; Klimisch score: 1 Consortium
Toxicity to microorganisms Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 209; Klimisch score: 1 Covestro Deutschland AG
Biodegradation in water: screening tests Robust Study Summary - Title: Mikrobiologische Untersuchungen von Hexamethylendiisocyanat (Desmodur H); Author: Bayer AG; Year: 1983; Guideline: 301C; Klimisch score: 2 Consortium
Biodegradation in water: screening tests Right to refer to study - Title: Mikrobiologische Untersuchungen von Hexamethylendiisocyanat (Desmodur H); Author: Bayer AG; Year: 1983; Guideline: 301C; Klimisch score: 2 Covestro Deutschland AG
Adsorption / desorption Robust Study Summary - Title: QSAR Estimations for HDI (CAS 822-06-1); Author: Bayer MaterialScience AG; Year: 2009; Guideline: 106; Klimisch score: 2 Consortium
Adsorption / desorption Right to refer to study - Title: QSAR Estimations for HDI (CAS 822-06-1); Author: Bayer MaterialScience AG; Year: 2009; Guideline: 106; Klimisch score: 2 Covestro Deutschland AG
CSR CSR Consortium