We're using cookies to improve your experience. Click here to find out more.

You are here: Home> South Korea>K-REACH>CAS 9048-57-1> CAS 9048-57-1 | Data Package > 1000 t/a (Read-Across)

Product Zoom Image

CAS 9048-57-1 | Data Package > 1000 t/a (Read-Across)

Price: POA

Product Features:

Includes:

Study name Short Description Data Owner
Toxicological | Skin sensitisation Robust Study Summary -- Title: Identification of chemical respiratory allergens: dose-response relationships in the mouse IgE test. | Author: Hilton J et al. | Year: 1995 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Characterization of murine immune responses to allergenic diisocyanates. | Author: Dearman RJ Spence LM & Kimber I | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Skin sensitisation Robust Study Summary -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Skin sensitisation Right to refer to study -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS and Friedman MA | Year: 1984 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: An In Vivo Alkaline Comet Assay of 4,4'-Diphenylmethane Diisocyanate by Nose-Only Inhalation in Male Wistar Rats | Author: Randazzo J. | Year: 2017 | Guideline: 489 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Genetic toxicity in vivo Right to refer to study -- Title: An In Vivo Alkaline Comet Assay of 4,4'-Diphenylmethane Diisocyanate by Nose-Only Inhalation in Male Wistar Rats | Author: Randazzo J. | Year: 2017 | Guideline: 489 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: MDI: bone marrow micronucleus assay following inhalation exposure to the rat | Author: Pauluhn J & Gollapudi B | Year: 2001 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Genetic toxicity in vivo Right to refer to study -- Title: MDI: bone marrow micronucleus assay following inhalation exposure to the rat | Author: Pauluhn J & Gollapudi B | Year: 2001 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Diphenylmethane 4,4'-diisocyanate (4,4'-MDI) - Acute inhalation toxicity in rats | Author: Pauluhn J | Year: 2008 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: Diphenylmethane 4,4'-diisocyanate (4,4'-MDI) - Acute inhalation toxicity in rats | Author: Pauluhn J | Year: 2008 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Desmodur 44 V 20 L: acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks) | Author: Pauluhn J | Year: 2008 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: Desmodur 44 V 20 L: acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks) | Author: Pauluhn J | Year: 2008 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: OECD Guideline 403 acute inhalation toxicity study for the no-longer-polymer (NLP) reaction product of 4,4’-MDI and diproplylene glycol (4,4’-MDI/DPG; EC 701-041-3), Study no. Laboratory Project Study ID 181018 | Author: J. A. Hotchkiss, L. J. Weidemoyer, | Year: 2020 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: OECD Guideline 403 acute inhalation toxicity study for the no-longer-polymer (NLP) reaction product of 4,4’-MDI and diproplylene glycol (4,4’-MDI/DPG; EC 701-041-3), Study no. Laboratory Project Study ID 181018 | Author: J. A. Hotchkiss, L. J. Weidemoyer, | Year: 2020 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX Buller RH & Geil RG | Year: 1964 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX Buller RH & Geil RG | Year: 1964 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Report 4,4'-MDI/DPG/HMWP Repeated dose 28-day inhalation toxicity study in Wistar rats liquid aerosol exposure with recovery period, Study no. 40I0338/18I093 | Author: Dr. Lan Ma-Hock et al. | Year: 2021 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Toxicological | Repeated dose toxicity: inhalation Right to refer to study -- Title: Report 4,4'-MDI/DPG/HMWP Repeated dose 28-day inhalation toxicity study in Wistar rats liquid aerosol exposure with recovery period, Study no. 40I0338/18I093 | Author: Dr. Lan Ma-Hock et al. | Year: 2021 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Prenatal toxicity of polymeric MDI in rats. Aerosol inhalation. 3 vols | Author: Gamer AO | Year: 1994 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Prenatal toxicity of polymeric MDI in rats. Aerosol inhalation. 3 vols | Author: Gamer AO | Year: 1994 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Prenatal toxicity if inhaled polymeric methylenediphenyl diisocyanate (MDI) aerosols in pregnant Wistar rats. | Author: Gamer A et al. | Year: 2000 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Embryotoxicity study of monomeric 4,4'-methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats | Author: Buschmann J Koch W Fuhst R & Heinrich U | Year: 1996 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Teratogenicity study of monomeric 4,4'-methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats | Author: Buschmann J | Year: 1994 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Band 1 - 3 | Author: Hoymann HG, Buschmann J, Heinrich U & Bartsch W | Year: 1995 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Chronic toxicity/carcinogenicity inhalation study of polymeric methylenediphenyl diisocyanate aerosol in rats. 3 vols | Author: Reuzel PGJ et al. | Year: 1990 | Guideline: 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Toxicity to reproduction Right to refer to study -- Title: Chronic toxicity/carcinogenicity inhalation study of polymeric methylenediphenyl diisocyanate aerosol in rats. 3 vols | Author: Reuzel PGJ et al. | Year: 1990 | Guideline: 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Acute, Subacute, and Subchronic Inhalation Toxicity Studies of Respirable Polymeric Methylene Diphenyl Diisocyanate (Polymeric MDI) Aerosol in Rats | Author: Reuzel PGJ et al. | Year: 1994 | Guideline: 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 9016-87-9 | Polymeric MDI)		 -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Acute Toxicity Test with 4,4'-MDI/DPG, Study no. 2018/0095/01 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-040-8 / 4,4'-MDI / DPG)		 -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Acute Toxicity Test with 4,4'-MDI/DPG, Study no. 2018/0095/01 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-040-8 / 4,4'-MDI / DPG)		 -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/03 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/03 | Author: Neuhahn, A. | Year: 2020 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2019/0023/02 | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2019/0023/02 | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2018/0095/03DA) | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP, Study no. 2018/0095/03DA) | Author: Neuhahn, A. | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted)Author,Study no. 2019/0023/02 | Author: CURRENTA GmbH & Co. OHG | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Daphnia sp., Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted)Author,Study no. 2019/0023/02 | Author: CURRENTA GmbH & Co. OHG | Year: 2020 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: CURRENTA GmbH & Co. OHG, 2020, Daphnia sp., Acute Immobilisation Test with MDI/PPG4000, Study no. 2020/0030/01 | Author: CURRENTA GmbH & Co. OHG | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: CURRENTA GmbH & Co. OHG, 2020, Daphnia sp., Acute Immobilisation Test with MDI/PPG4000, Study no. 2020/0030/01 | Author: CURRENTA GmbH & Co. OHG | Year: 2021 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Alga Growth Inhibition Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Alga Growth Inhibition Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Alga, Growth Inhibition Test with 4,4'-MDI/DPG, Study no. 2018/0095/02 | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (EC 701-040-8 / 4,4'-MDI / DPG)		 -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Alga, Growth Inhibition Test with 4,4'-MDI/DPG, Study no. 2018/0095/02 | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (EC 701-040-8 / 4,4'-MDI / DPG)		 -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Alga, Growth Inhibition Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/01 | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Alga, Growth Inhibition Test with 4,4'-MDI/DPG/HMWP (Monomer depleted), Study no. 2019/0023/01 | Author: Neuhahn A. | Year: 2020 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y.
Read-Across (EC 701-041-3 | 4,4'-MDI/DPG/HMWP)		 -
Environmental | Hydrolysis Robust Study Summary -- Title: Determination of hydrolysis behavior of 4,4'-MDI under homogenous reaction conditions | Author: Neluand M. | Year: 2021 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Environmental | Hydrolysis Right to refer to study -- Title: Determination of hydrolysis behavior of 4,4'-MDI under homogenous reaction conditions | Author: Neluand M. | Year: 2021 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Environmental | Hydrolysis Robust Study Summary -- Title: Study on the fate of polymeric MDI in water | Author: Yakabe Y Mori E and Tadokoro H | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -
Environmental | Hydrolysis Right to refer to study -- Title: Study on the fate of polymeric MDI in water | Author: Yakabe Y Mori E and Tadokoro H | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 101-68-8 | EC 202-966-0 | 4,4'-MDI)		 -