You are here: Home> Turkey>TR-REACH>CAS 1065336-91-5> CAS 1065336-91-5 | Data Package > 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Analytical Method | Author: Ciba SC Inc | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Analytical Method | Author: Ciba SC Inc | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Analysenbericht: Bestimmung des Erstarrungspunktes mittes DSC-Analyse | Author: Ciba Inc. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Analysenbericht: Bestimmung des Erstarrungspunktes mittes DSC-Analyse | Author: Ciba Inc. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Sidepunkt Siedebereich | Author: Ciba-Geigy Ltd | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Sidepunkt Siedebereich | Author: Ciba-Geigy Ltd | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Relative Density of Test Item | Author: BASF- The Chemical Company | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Relative Density of Test Item | Author: BASF- The Chemical Company | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Tinuvin 292 | Author: Ciba-Geigy Ltd. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Tinuvin 292 | Author: Ciba-Geigy Ltd. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of Water Solubility of Test Item according to OECD TG 105 | Author: TAOH | Year: 2007 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of Water Solubility of Test Item according to OECD TG 105 | Author: TAOH | Year: 2007 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Report on Partition Coefficient | Author: Ciba-Geigy Ltd. | Year: 1981 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Report on Partition Coefficient | Author: Ciba-Geigy Ltd. | Year: 1981 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Calculation | Author: No author provided | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: QSAR: Dissociation Constant on Test Item | Author: Ciba S.p.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Title: QSAR: Dissociation Constant on Test Item | Author: Ciba S.p.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: Calculation of Dissociation Constant on Test Item | Author: Ciba S.p.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Title: Calculation of Dissociation Constant on Test Item | Author: Ciba S.p.A. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Bestimmung der Oberflächenspannung gemäss Vorschrift KB-45/8 und der Viskosität | Author: Ciba SC | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Bestimmung der Oberflächenspannung gemäss Vorschrift KB-45/8 und der Viskosität | Author: Ciba SC | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Report on Skin Irritation in the Rabbit After Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Report on Skin Irritation in the Rabbit After Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Report on Skin Irritation in the Rabbit after Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Report on Skin Irritation in the Rabbit after Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Report on Eye Irritation in the Rabbit After Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report on Eye Irritation in the Rabbit After Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Report on Eye Irritation in the Rabbit after Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report on Eye Irritation in the Rabbit after Single Application of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: FAT 75314/A SKIN SENSITIZATION TEST IN THE GUINEA PIG MAXIMIZATION TEST | Author: Ciba-Geigy | Year: 1988 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: FAT 75314/A SKIN SENSITIZATION TEST IN THE GUINEA PIG MAXIMIZATION TEST | Author: Ciba-Geigy | Year: 1988 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 Maximization Test | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 41556-26-7) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 Maximization Test | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 41556-26-7) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs | Author: Ciba-Geigy | Year: 1983 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs | Author: Ciba-Geigy | Year: 1983 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 41556-26-7) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Report on Skin Sensitizing (Contact Allergenic) Effect in Guinea Pigs of TK 12576 | Author: Ciba-Geigy | Year: 1982 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 41556-26-7) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella and Escherichia/Liver Microsome Test | Author: Ciba-Geigy | Year: 1980 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella and Escherichia/Liver Microsome Test | Author: Ciba-Geigy | Year: 1980 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In-vitro chromosome aberration assay in V79 cells | Author: BASF SE | Year: 2010 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In-vitro chromosome aberration assay in V79 cells | Author: BASF SE | Year: 2010 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Gene mutation assay in chinese hamster V79 cells in-vitro with TINUVIN 770 (TK 10665) | Author: Harlan | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Gene mutation assay in chinese hamster V79 cells in-vitro with TINUVIN 770 (TK 10665) | Author: Harlan | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella/Mammalian-microsome mutagenicity test with TK 10665 | Author: Ciba-Geigy | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella/Mammalian-microsome mutagenicity test with TK 10665 | Author: Ciba-Geigy | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella and Escherichia coli/Liver micorsome test (Test for mutagenic properties in bacteria) | Author: Hattori M | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Salmonella and Escherichia coli/Liver micorsome test (Test for mutagenic properties in bacteria) | Author: Hattori M | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Evaluation of the ability of TK 10665 (Tinuvin 770) to induce chromosome aberrations in cultured peripheral human lymphocytes. | Author: Notox | Year: 2007 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Evaluation of the ability of TK 10665 (Tinuvin 770) to induce chromosome aberrations in cultured peripheral human lymphocytes. | Author: Notox | Year: 2007 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Tinuvin 292 (TK 12576) Micronucleus Assay in Bone Marrow Cells of the Mouse Oral Administration | Author: Harlan | Year: 2013 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Tinuvin 292 (TK 12576) Micronucleus Assay in Bone Marrow Cells of the Mouse Oral Administration | Author: Harlan | Year: 2013 | Guideline: 474 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Report on Acute Oral LD50 in the Rat of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report on Acute Oral LD50 in the Rat of TK 12576 | Author: Ciba-Geigy | Year: 1981 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Report on Acute Oral LD50 in the Rat of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Report on Acute Oral LD50 in the Rat of TK 12576 | Author: Ciba-Geigy | Year: 1979 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute dermal LD50 in the rat of TK 10655 | Author: Ciba-Geigy | Year: 1975 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute dermal LD50 in the rat of TK 10655 | Author: Ciba-Geigy | Year: 1975 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Extended One Generation Reproductive Toxicity Study including Cohorts 1 2 and 3 of Bis(2266-tetramethyl-4-piperidyl) Sebacate by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 443 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Extended One Generation Reproductive Toxicity Study including Cohorts 1 2 and 3 of Bis(2266-tetramethyl-4-piperidyl) Sebacate by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 443 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 90 Day dietary toxicity study in dogs with compound TK 10665 | Author: Geigy Pharmaceuticals | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: 90 Day dietary toxicity study in dogs with compound TK 10665 | Author: Geigy Pharmaceuticals | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: TK 10665 Toxicity to rats dietary administration for 13 weeks | Author: Huntingdon | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: TK 10665 Toxicity to rats dietary administration for 13 weeks | Author: Huntingdon | Year: 1974 | Guideline: 408 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of TINUVIN® 292 by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of TINUVIN® 292 by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Repeated dose 28-day toxicity study with a recovery period of 2 weeks in Wistar rats administration by gavage | Author: BASF SE | Year: 2010 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Repeated dose 28-day toxicity study with a recovery period of 2 weeks in Wistar rats administration by gavage | Author: BASF SE | Year: 2010 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of Bis(2266-tetramethyl-4-piperdyl) sebacate by Dietary Administration in Rats | Author: Charles River | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of Bis(2266-tetramethyl-4-piperdyl) sebacate by Dietary Administration in Rats | Author: Charles River | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Preparation TK 10655 Report on the 28-day toxicity study oral administration - rat | Author: Ciba-Geigy | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Preparation TK 10655 Report on the 28-day toxicity study oral administration - rat | Author: Ciba-Geigy | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: TK 10665 Oral toxicity study in rats (daily administration for 4 weeks) | Author: Huntingdon | Year: 1972 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: TK 10665 Oral toxicity study in rats (daily administration for 4 weeks) | Author: Huntingdon | Year: 1972 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal Developmental Toxicity Study of TINUVIN® 292 by Oral Gavage in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal Developmental Toxicity Study of TINUVIN® 292 by Oral Gavage in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal Developmental Toxicity Study of Bis(2266-tetramethyl-4- piperidyl) sebacate by Oral Gavage in Rabbits | Author: Charles River Laboratories | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal Developmental Toxicity Study of Bis(2266-tetramethyl-4- piperidyl) sebacate by Oral Gavage in Rabbits | Author: Charles River Laboratories | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Extended One Generation Reproductive Toxicity Study including Cohorts 1 2 and 3 of Bis(2266-tetramethyl-4-piperidyl) Sebacate by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 443 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Extended One Generation Reproductive Toxicity Study including Cohorts 1 2 and 3 of Bis(2266-tetramethyl-4-piperidyl) Sebacate by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2020 | Guideline: 443 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of TINUVIN® 292 by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of TINUVIN® 292 by Dietary Administration in Rats | Author: Charles River Laboratories Den Bosch BV | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of Bis(2266-tetramethyl-4-piperdyl) sebacate by Dietary Administration in Rats | Author: Charles River | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined 28-Day Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test of Bis(2266-tetramethyl-4-piperdyl) sebacate by Dietary Administration in Rats | Author: Charles River | Year: 2021 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: A one-generation reproduction toxicity study of TK 10665 (Tinuvin 770) in rats by oral gavage | Author: Notox | Year: 2007 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: A one-generation reproduction toxicity study of TK 10665 (Tinuvin 770) in rats by oral gavage | Author: Notox | Year: 2007 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 52829-07-9 | EC 258-207-9 | bis(2,2,6,6-tetramethylpiperidin-4-yl) sebacate) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Report on the Test for Acute Toxicity of TK 12576 to Bluegill | Author: Ciba Geigy Ltd. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Report on the Test for Acute Toxicity of TK 12576 to Bluegill | Author: Ciba Geigy Ltd. | Year: 1984 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Tinuvin 292 (TK 12576) - Acute Toxicity Study with the Zebrafish (Danio rerio) | Author: BASF SE | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Tinuvin 292 (TK 12576) - Acute Toxicity Study with the Zebrafish (Danio rerio) | Author: BASF SE | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Tinuvin 292 (TK 12576) - Growth inhibition study in unicellular green algae Desmodesmus subspicatus CHODAT | Author: BASF SE | Year: 2010 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Tinuvin 292 (TK 12576) - Growth inhibition study in unicellular green algae Desmodesmus subspicatus CHODAT | Author: BASF SE | Year: 2010 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Report on the test for inhibitory concentration of TK 12576 on aerobic bacteria | Author: Ciba-Geigy Ltd. | Year: 1988 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Report on the test for inhibitory concentration of TK 12576 on aerobic bacteria | Author: Ciba-Geigy Ltd. | Year: 1988 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Tinuvin 292 (TK 12576) - Daphnia magna Reproduction Test | Author: BASF SE | Year: 2010 | Guideline: 211 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Tinuvin 292 (TK 12576) - Daphnia magna Reproduction Test | Author: BASF SE | Year: 2010 | Guideline: 211 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Bioaccumulation test in Fish with TK 12576 | Author: Faculty of Science Gakushuin University | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Right to refer to study -- Title: Bioaccumulation test in Fish with TK 12576 | Author: Faculty of Science Gakushuin University | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis of Tinuvin 292 | Author: Ciba Inc. | Year: 2008 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis of Tinuvin 292 | Author: Ciba Inc. | Year: 2008 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of TK 12576 Modified OECD Screening Test No. 301 E | Author: Ciba-Geigy Ltd. | Year: 1983 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation of TK 12576 Modified OECD Screening Test No. 301 E | Author: Ciba-Geigy Ltd. | Year: 1983 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: SRC PCKOCWIN v2.00 | Author: BASF SE | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 41556-26-7 | EC 255-437-1 | bis(1,2,2,6,6-pentamethylpiperidin-4-yl) sebacate) |
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| Environmental | Adsorption/desorption | Right to refer to study -- Title: SRC PCKOCWIN v2.00 | Author: BASF SE | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 41556-26-7 | EC 255-437-1 | bis(1,2,2,6,6-pentamethylpiperidin-4-yl) sebacate) |
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| Phys-Chem | Stability: thermal, sunlight, metals | Robust Study Summary -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Guideline: 113 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Stability: thermal, sunlight, metals | Right to refer to study -- Title: BASF_SIK-Nr. 09/1198; Evaluation of physical and chemical properties according to Directive 67/548/EC Annex V | Author: BASF - The Chemical Company | Year: 2009 | Guideline: 113 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |