You are here: Home> Turkey>TR-REACH>CAS 106-89-8> CAS 106-89-8 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals, 4th Edition | Author: Verschueren, K. | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: The Merck index : an encyclopedia of chemicals, drugs, and biologicals | Author: O'Niel M., Smith A., Heckelman | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics. | Author: Weast R., Astle M., Beyer W. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals | Author: Verschueren, Karel | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Organic Solvents: Physical Properties and Methods of Purification | Author: Riddick, J. A. and Bunger, W.B. | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Chlorohydrins | Author: Riesser, G. H. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Physical Properties of Organic Chemicals | Author: Howard P., Meylan W. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: 3648. Epichlorohydrin | Author: Budavari et al. | Year: 1996 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Epichlorohydrin | Author: Verschueren K. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: 3648. Epichlorohydrin | Author: O'Neil, M.J. (ed.). | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: 1-chloro-2,3-epoxypropane | Author: Howard P., Meylan W. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry an Physics | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: No information | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Organic Solvents: Physical Properties and Methods of Purification, 3rd ed. | Author: Riddick, J.A., Bunger, W.B. | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor Pressure of Epichlorohydrin and Glycidyl Methacrylate. | Author: Griffin, K.A. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapor Pressure of Epichlorohydrin and Glycidyl Methacrylate. | Author: Griffin, K.A. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Assessment of the Impact of the Emission of Certain Organochlorine Compounds on the Aquatic Environment. Part III : Epichlorohydrin | Author: Krijgsheld K.R., van der Gen A. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Data compilation tables of properties of pure compounds. | Author: Daubert, T.E. and Danner, R. P. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: DIPPR® Data Compilation of Pure Chemicals Properties | Author: Rowley, R.L., et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Applicability and Limitation of QSARs for the Toxicity of Electrophilic Chemicals | Author: Harder, Angela et al. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: A quantitative structure-activity relationship for the acute toxicity of some epoxy compounds to the guppy | Author: Deneer J.W et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Assessment of the Impact of the Emission of Certain Organochlorine Compounds on the Aquatic Environment. Part III : Epichlorohydrin | Author: Krijgsheld K.R., van der Gen A. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Handbook of Environmental Data on Organic Chemicals | Author: Verschueren K. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Handbook of Physical Properties of Organic Chemicals. | Author: Howard, P.H. and Meylan, W.M. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: AQUASOL Database of Aqueous Solubility. | Author: Yalkowsky, S. et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Organic Solvents: Physical Properties and Methods of Purification, 3rd ed. | Author: Riddick, J.A., Bunger, W.B | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Sicherheitstechnische Kenngroessen reiner Gase und Fluessigkeiten | Author: Brandes, E and Moeller, W. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Sax's dangerous properties of industrial materials, 8th ed. , Vol. II | Author: Lewis, R.J. SR. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: 3658. Epichlorohydrin | Author: O'Niel M., Smith A., Heckelman | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Sicherheitstechnische Kenngroessen | Author: Brandes, Elisabeth and Moeller, Wolfgang | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Epoxy Compounds | Author: Gardiner T., Waechter J., Stevenson D., | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Sicherheitstechnische Kenngroessen reiner Gase und Fluessigkeiten | Author: Brandes, E and Moeller, W.; | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Organic Solvents: Physical Properties and Methods of Purification, 3rd ed. | Author: Riddick, J.A., Bunger, W.B. | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Die Kinetik der Hydrolyses von Epichlorohydrin in verdünnten wässrigen Lösungen | Author: Pringer, V.O. | Year: 1980 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Assessment of the impact of the emission of certain organochlorine compounds on the aquatic environment : Part III: Epichlorohydrin | Author: Krijgsheld, K.R., and van der Gen, A. | Year: 1986 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis of epichlorohydrin at 20 deg C and at 35 deg C | Author: Solvay Pharmaceuticals Int. | Year: 2001 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis of epichlorohydrin at 20 deg C and at 35 deg C | Author: Solvay Pharmaceuticals Int. | Year: 2001 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Environmental Impact Analysis, Product Biodegradability Testing | Author: Union Carbide Corporation | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Environmental Impact Analysis, Product Biodegradability Testing | Author: Union Carbide Corporation | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals based on the CSCL Japan | Author: CITI | Year: 1992 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals based on the CSCL Japan | Author: CITI | Year: 1992 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Determination of the biodegradation rate of epichlorohydrin in Texas Operations wastewater utilizing activated sludges from Texas Operations. | Author: The Dow Chemical Company | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Right to refer to study -- Title: Determination of the biodegradation rate of epichlorohydrin in Texas Operations wastewater utilizing activated sludges from Texas Operations. | Author: The Dow Chemical Company | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Verfahren zur Bestimmung der biologischen Abbaubarkeit wasserloslicher chlororganischer Verbindungen | Author: BASF | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 107-05-1 | EC 203-457-6 | Allyl chloride) |
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| Environmental | Biodegradation in water and sediment: simulation tests | Right to refer to study -- Title: Verfahren zur Bestimmung der biologischen Abbaubarkeit wasserloslicher chlororganischer Verbindungen | Author: BASF | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 107-05-1 | EC 203-457-6 | Allyl chloride) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The acute toxicity of 47 industrial chemicals to fresh and saltwater fishes | Author: GW Dawson et al. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: A study to assess the influence of age on the response of Fathead Minnows in static acute toxicity tests | Author: The Dow Chemical Company | Year: 1982 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: A study to assess the influence of age on the response of Fathead Minnows in static acute toxicity tests | Author: The Dow Chemical Company | Year: 1982 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: A study to assess the influence of age on the response of fathead minnows in static acute toxicity tests | Author: Mayes M.A., Alexander H.C., Dill D.C. | Year: 1983 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The acute toxicity of 47 industrial chemicals to fresh and saltwater fishes | Author: GW Dawson et al. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The precision of daphnid (Daphnia magna Straus, 1820) static acute toxicity tests, | Author: The Dow Chemical Company | Year: 1985 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: The precision of daphnid (Daphnia magna Straus, 1820) static acute toxicity tests, | Author: The Dow Chemical Company | Year: 1985 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The precision of daphnid (Daphnia magna Straus, 1820) static acute toxicity tests | Author: Gersich F.M., et al. | Year: 1986 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: The precision of daphnid (Daphnia magna Straus, 1820) static acute toxicity tests | Author: Gersich F.M., et al. | Year: 1986 | Guideline: ASTM E 729-80 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: The Toxicity of Epichlorohydrin to the Alga Selenastrum Capricornutum | Author: Solvay Pharmaceuticals Int. | Year: 2001 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: The Toxicity of Epichlorohydrin to the Alga Selenastrum Capricornutum | Author: Solvay Pharmaceuticals Int. | Year: 2001 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: The toxicity of chemicals to green alga, Selenastrum capricornutum Printz. | Author: The Dow Chemical Company | Year: 1982 | Guideline: EPA 600/9-78-018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: The toxicity of chemicals to green alga, Selenastrum capricornutum Printz. | Author: The Dow Chemical Company | Year: 1982 | Guideline: EPA 600/9-78-018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Comparison of the toxicity thresholds of water pollution to bacteria, algae, and protozoa in the cell multiplication inhibition test | Author: G Bringmann and R Kuhn | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Comparison of the toxicity thresholds of water pollutants to bacteria, algae, and protozoa in the cell multiplication inhibition test | Author: G Bringmann and R Kuhn | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Epi-chlorohvdrin: d Metabolism and Toxicity in the Rat | Author: Fakhouri, G. and Jones, A.R. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Tissue distribution and excretion of 14C- Epichlorohydrin in male and female rats | Author: Weigel, W.W., Plotnick, H.B. and Conner, W.L. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Preliminary observations on the urinary metabolites of epichlorohydrin and allyl chloride. | Author: The Dow Chemical Company | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Preliminary observations on the urinary metabolites of epichlorohydrin and allyl chloride. | Author: The Dow Chemical Company | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Disposition and metabolism of [2-14C]epichlorohydrin after oral administration to rats | Author: Gingell R., et al. | Year: 1985 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetics of epichlorohydrin (EPI) administered to rats by gavage or inhalation. | Author: The Dow Chemcial Company | Year: 1979 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Pharmacokinetics of epichlorohydrin (EPI) administered to rats by gavage or inhalation. | Author: The Dow Chemcial Company | Year: 1979 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Results of Range finding Toxicological Tests on Epichlorohydrin | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Results of Range finding Toxicological Tests on Epichlorohydrin | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range Finding Tests on Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range Finding Tests on Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Further experience with the range finding test in the industrial toxicology laboratory | Author: Smyth, H.F. and Carpenter, C.P. | Year: 1948 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Further experience with the range finding test in the industrial toxicology laboratory | Author: Smyth, H.F. and Carpenter, C.P. | Year: 1948 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: A comparison of single-dose oral LD50's for SPB: (Sprague-Dawley) rats and CDF (Fischer 344-derived) rats. | Author: The Dow Chemical Company | Year: 1980 | Guideline: EPA OPP 81-1 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: A comparison of single-dose oral LD50's for SPB: (Sprague-Dawley) rats and CDF (Fischer 344-derived) rats. | Author: The Dow Chemical Company | Year: 1980 | Guideline: EPA OPP 81-1 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Results of rangefinding toxicological tests on epichlorohydrin. | Author: The Dow Chemcial Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Results of rangefinding toxicological tests on epichlorohydrin. | Author: The Dow Chemcial Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Epichlorohydrin: 1-hour LC50 determination in Fischer 344 rats. | Author: The Dow Chemical Company | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Epichlorohydrin: 1-hour LC50 determination in Fischer 344 rats. | Author: The Dow Chemical Company | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute Percutaneous Absorption Potential of Epichlorohydrin. | Author: The Dow Chemical Company | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute Percutaneous Absorption Potential of Epichlorohydrin. | Author: The Dow Chemical Company | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Results of rangefinding toxicological tests on epichlorohydrin. | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Results of rangefinding toxicological tests on epichlorohydrin. | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Range Finding Tests of Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Range Finding Tests of Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Further experience with the range finding test in the industrial toxicology laboratory | Author: Smyth, Jr. H.F. and Carpenter, C.P | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Further experience with the range finding test in the industrial toxicology laboratory | Author: Smyth, Jr. H.F. and Carpenter, C.P | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Results of range finding toxicological tests on epichlorohydrin. | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Results of range finding toxicological tests on epichlorohydrin. | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Etude experimentale de l'intoxication par l'epichlorhydrine | Author: Pallade S., Dorobantu M., Gabrielescu E. | Year: 1967 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Toxicology Studies | Author: Union Carbide Corporation | Year: 1958 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Range Finding Tests on Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Range Finding Tests on Epichlorohydrin | Author: Mellon Institute of Industrial Research | Year: 1945 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Experimental carcinogenicity and acute toxicity of representative epoxides | Author: Weil C.S., et al. | Year: 1963 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Chemical burns of the rabbit cornea | Author: Carpenter, C.P. and Smyth Jr., H.F. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 107-05-1 | EC 203-457-6 | Allyl chloride) |
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| Toxicological | Eye irritation | Right to refer to study -- Title: Chemical burns of the rabbit cornea | Author: Carpenter, C.P. and Smyth Jr., H.F. | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 107-05-1 | EC 203-457-6 | Allyl chloride) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Allergenicity of epoxy resins in the guinea pig | Author: Thorgeirsson A., Fregert S. | Year: 1977 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: toxicological properties and industrial handling hazards of guinea pig skin sensitization study on epichlorohydrin | Author: The Dow Chemical Company | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: toxicological properties and industrial handling hazards of guinea pig skin sensitization study on epichlorohydrin | Author: The Dow Chemical Company | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A series of Guinea pig sensitization tests for structure-activity correlation-epoxides. | Author: The Dow Chemical Company | Year: 1986 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: A series of Guinea pig sensitization tests for structure-activity correlation-epoxides. | Author: The Dow Chemical Company | Year: 1986 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicity studies of epichlorohydrin in Sprague-Dawley rats. | Author: Daniel, F.B., et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Epicholorohydrin - Subchronic studies. I. A 90-day inhalation study in laboratory rodents, (Fischer 344 rats, Sprague-Dawley rats and B6C3F1 mice.) | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Epicholorohydrin - Subchronic studies. I. A 90-day inhalation study in laboratory rodents, (Fischer 344 rats, Sprague-Dawley rats and B6C3F1 mice.) | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 90-day inhalation toxicity study of epichlorohydrin in laboratory rodents | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 90-day inhalation toxicity study of epichlorohydrin in laboratory rodents | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Epicholorohydrin - Subchronic studies. I. A12 Day Inhalation Study In Laboratory Rodents (Fischer 344 rats, Sprague-Dawley rats and B6C3F1 mice.) | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Epicholorohydrin - Subchronic studies. I. A12 Day Inhalation Study In Laboratory Rodents (Fischer 344 rats, Sprague-Dawley rats and B6C3F1 mice.) | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenic action of aromatic epoxy resins | Author: Andersen, M., et al. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Comparison of the mutagenic potency of 2-chloroethanol, 2-bromoethanol, 1,2-epoxybutane, epichlorohydrin and glycidaldehyde in Klebsiella pneumoniae, Drosophila melanogaster and L5178Y mouse lymphoma cells | Author: Knaap, A.G.A.C., Voogd, C.E. and Kramers, P.G.N. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Evaluation of epichlorohydrin for mutagenicity in the bacterial assay system. I. Tests with epichlorohydrin and with urine from epichlorohydrin -exposed and non-exposed workers. | Author: The Dow Chemical Company | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Evaluation of epichlorohydrin for mutagenicity in the bacterial assay system. I. Tests with epichlorohydrin and with urine from epichlorohydrin -exposed and non-exposed workers. | Author: The Dow Chemical Company | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Effects of a-chlorohydrin and related compounds on the reproductive organs and fertility of the male rat | Author: E. R. A. Cooper, A. R. Jones And H. Jackson | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Effects of epichlorohydrin on male and female reproduction in Long-Evans rats | Author: Toth G.P., Zenick H., Smith M.K. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Inhalation toxicity of epichlorohydrin : Effects on fertility in rats and rabbits | Author: John J.A., et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: THE EFFECTS OF INHALED EPICHLOROHYDRIN ON THE SEMEN OF RABBITS AND ON THE FERTILITY OF MALE AND FEMALE RATS | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: THE EFFECTS OF INHALED EPICHLOROHYDRIN ON THE SEMEN OF RABBITS AND ON THE FERTILITY OF MALE AND FEMALE RATS | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Inhalation toxicity of epichlorohydrin : Effects on fertility in rats and rabbits | Author: John J.A., et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: The effects of inhaled epichlorohydrin on the semen of rabbitsand on the fertility of male and female rats | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: The effects of inhaled epichlorohydrin on the semen of rabbitsand on the fertility of male and female rats | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Epichlorohydrin - Subchronic Studies IV. The effects of maternally inhaled epichlorohydrin on rat and rabbit embryonal and fetal development. | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Epichlorohydrin - Subchronic Studies IV. The effects of maternally inhaled epichlorohydrin on rat and rabbit embryonal and fetal development. | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic evaluation of inhaled epichlorohydrin and allyl chloride in rats and rabbits | Author: John J.A., et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Teratologic evaluation of inhaled epichlorohydrin and allyl chloride in rats and rabbits | Author: John J.A., et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Epichlorohydrin - Subchronic Studies IV. The effects of maternally inhaled epichlorohydrin on rat and rabbit embryonal and fetal development. | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Epichlorohydrin - Subchronic Studies IV. The effects of maternally inhaled epichlorohydrin on rat and rabbit embryonal and fetal development. | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic evaluation of inhaled epichlorohydrin and allyl chloride in rats and rabbits | Author: John J.A., et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Teratologic evaluation of inhaled epichlorohydrin and allyl chloride in rats and rabbits | Author: John J.A., et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratogenic evaluation of epichlorohydrin in the mouse and rat and glycidol in the mouse | Author: Marks, T.A., Gerling, F.S. and Staples, R.E. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: The Effects of Inhaled Epichlorohydrin on the semen of Rabbits and on the fertility of male and female Rats | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: The Effects of Inhaled Epichlorohydrin on the semen of Rabbits and on the fertility of male and female Rats | Author: The Dow Chemical Company | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |