You are here: Home> South Korea>K-REACH>CAS 26447-40-5> CAS 26447-40-5 | Data Package 10 - 100 t/a (Affiliates of EU Consortium and III members).
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Boiling point test | Author: Fisk and Langner | Year: 1995 | Guideline: 103 | Klimisch score: 1 Read-across (CAS 32055-14-4) |
MDI-MDA Consortium |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Boiling point test | Author: Fisk and Langner | Year: 1995 | Guideline: 103 | Klimisch score: 1 Read-across (CAS 32055-14-4) |
III |
| Phys-Chem | Density | Robust Study Summary -- Title: Relative density test | Author: Fisk and Langner | Year: 1995 | Guideline: 109 | Klimisch score: 1 Read-across (CAS 101-68-8) |
MDI-MDA Consortium |
| Phys-Chem | Density | Right to refer to study -- Title: Relative density test | Author: Fisk and Langner | Year: 1995 | Guideline: 109 | Klimisch score: 1 Read-across (CAS 101-68-8) |
III |
| Phys-Chem | Water solubility | Robust Study Summary -- Author: West et al | Year: 2008 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions. | MDI-MDA Consortium |
| Phys-Chem | Water solubility | Right to refer to study -- Author: West et al | Year: 2008 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions. | III |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T | Year: 1991 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-across (CAS 101-68-8) |
MDI-MDA Consortium |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T | Year: 1991 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-across (CAS 101-68-8) |
Covestro |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS et al. | Year: 1984 | Adequacy: weight of evidence. | MDI-MDA Consortium |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI, MDI, p-TMXDI, IPDI, m-TMXDI, HMDI and m-TMI (modified Buehler method) | Author: Davis RA, Auletta CS et al. | Year: 1984 | Adequacy: weight of evidence. | American Cyanamid |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B Haas et al. | Year: 1998 | Guideline: B.13/14 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-across (CAS 101-68-8) |
MDI-MDA Consortium |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B Haas et al. | Year: 1998 | Guideline: B.13/14 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-across (CAS 101-68-8) |
Covestro |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | MDI-MDA Consortium |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Covestro |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: short term aquatic toxicity testing on invertebrates (Daphnia) | Author: Caspers et al, | Year: 1986 | Guideline: 202 | Klimisch score: 2 Read-across (CAS 9016-87-9) |
MDI-MDA Consortium |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: short term aquatic toxicity testing on invertebrates (Daphnia) | Author: Caspers et al, | Year: 1986 | Guideline: 202 | Klimisch score: 2 Read-across (CAS 9016-87-9) |
III |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: short term aquatic toxicity testing on fish | Author: Caspers et al, | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions. Read-across (CAS 9016-87-9) |
MDI-MDA Consortium |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: short term aquatic toxicity testing on fish | Author: Caspers et al, | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions. Read-across (CAS 9016-87-9) |
III |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Consortium study | Guideline: A.10 | Klimisch score: 1 | MDI-MDA Consortium |
| Phys-Chem | Flammability | Right to refer to study -- Title: Consortium study | Guideline: A.10 | Klimisch score: 1 | MDI-MDA Consortium |
| Toxicological | Eye irritation test | Robust Study Summary -- Title: in vivo eye irritation test | Author: Martins | Year: 1991 | Guideline: 405 | Klimisch score: 1 Read-across (CAS 101-68-8) |
MDI-MDA Consortium |
| Toxicological | Eye irritation | Right to refer to study -- Title: in vivo eye irritation test | Author: Martins | Year: 1991 | Guideline: 405 | Klimisch score: 1 Read-across (CAS 101-68-8) |
Covestro |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Author: Pauluhn | Year: 2008 | Guideline: 403 | Klimisch score: 1 | MDI-MDA Consortium |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Author: Pauluhn | Year: 2008 | Guideline: 403 | Klimisch score: 1 | Bayer |
| Toxicological | Acute toxicity: dermal (rabbit) | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX, Buller RH & Geil RG | Year: 1964 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. Read-Across (CAS 9016-87-9) |
MDI-MDA Consortium |
| Toxicological | Acute toxicity: dermal (rabbit) | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit | Author: Wazeter FX, Buller RH & Geil RG | Year: 1964 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. Read-Across (CAS 9016-87-9) |
Dow Chemical Company |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis test (as a function of the pH; abiotic degradation) | Author: Yakabe et al | Year: 1994 | Guideline: 111 | Klimisch score: 2 Read-across (CAS 32055-14-4) |
MDI-MDA Consortium |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis test (as a function of the pH; abiotic degradation) | Author: Yakabe et al | Year: 1994 | Guideline: 111 | Klimisch score: 2 Read-across (CAS 32055-14-4) |
III |
| Toxicological | Cytogenicitic assay / chromosomal abberation test (in vivo) | Robust Study Summary -- Title: Cytogenicitic assay / chromosomal abberation test (in vivo) | Author: Pauluhn and Gollapudi [Pauluhn et al] | Year: 2001 | Guideline: 474 | Klimisch score: 1 Read-across (CAS 101-68-8) |
MDI-MDA Consortium |
| Toxicological | Cytogenicitic assay / chromosomal abberation test (in vivo) | Right to refer to study -- Title: Cytogenicitic assay / chromosomal abberation test (in vivo) | Author: Pauluhn and Gollapudi | Year: 2001 | Guideline: 474 | Klimisch score: 1 Read-across (CAS 101-68-8) |
III |
| Eco-Tox | Growth inhibition study aquatic plants (algae) | Robust Study Summary -- Title: growth inhibition study aquatic plants (algae) | Author: Blom and Oldersma, | Year: 1994 | Guideline: 201 | Klimisch score: 2 Read-across (CAS 9016-87-9) |
MDI-MDA Consortium |
| Eco-Tox | Growth inhibition study aquatic plants (algae) | Right to refer to study -- Title: growth inhibition study aquatic plants (algae) | Author: Blom and Oldersma, | Year: 1994 | Guideline: 201 | Klimisch score: 2 Read-across (CAS 9016-87-9) |
III |