You are here: Home> Turkey>TR-REACH>CAS 26447-40-5> CAS 26447-40-5 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Summary on the vapour pressures of BASF own MDI substances and MDI modified substances (Prepolymers) | Author: BASF Polyurethanes GmbH | Year: 2018 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Summary on the vapour pressures of BASF own MDI substances and MDI modified substances (Prepolymers) | Author: BASF Polyurethanes GmbH | Year: 2018 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor pressure of MDi MI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapor pressure of MDi MI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Yakabe Y. | Year: 1997 | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: No information | Author: Yakabe Y. | Year: 1997 | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Waiver | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of 1-octanol/water partition coefficients of isocyanate compounds by an HPLC method | Author: Yakabe Y. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Waiver | - |
| Phys-Chem | Surface tension | Waiver | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: 114 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.12 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.12 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Pyrophoric Properties | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Pyrophoric Properties | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.13 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Explosive properties | Waiver | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Stability in organic solvents and identity of relevant degradation products | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Phys/Chem. Testing on a Sample of Suprasec 3050 | Author: Baker D. | Year: 2010 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Physico-chemical Properties Testing on a Sample of MDI Mixed Isomers (EC Number: 905-806-4) | Author: Shajad Younis | Year: 2019 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Stability: Dissociation constant | Waiver | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T. | Year: 1991 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T. | Year: 1991 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T. | Year: 1991 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Desmodur VP PU 1806: study for skin and eye irritation/corrosion in rabbits | Author: Märtins T. | Year: 1991 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Waiver | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI MDI p-TMXDI IPDI m-TMXDI HMDI and m-TMI (modified Buehler method) | Author: Davis R.A. et al. | Year: 1984 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: A Closed-Patch repeated insult dermal sensitization study in guinea pigs with TDI MDI p-TMXDI IPDI m-TMXDI HMDI and m-TMI (modified Buehler method) | Author: Davis R.A. et al. | Year: 1984 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Guinea Pig Sensitization - Maximization Test (Magnusson-Kligman Method) with Suprasec 2449 | Author: Mallory V.T. | Year: 2009 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Guinea Pig Sensitization - Maximization Test (Magnusson-Kligman Method) with Suprasec 2449 | Author: Mallory V.T. | Year: 2009 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Guinea Pig Sensitization - Maximization Test (Magnusson-Kligman Method) with Suprasec 2020 | Author: Mallory V.T. | Year: 2009 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Guinea Pig Sensitization - Maximization Test (Magnusson-Kligman Method) with Suprasec 2020 | Author: Mallory V.T. | Year: 2009 | Adequacy: weight of evidence. | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B. et al. | Year: 1998 | Guideline: EU B.13/14 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Waiver | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Waiver | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: An In Vivo Alkaline Comet Assay of 4,4'-Diphenylmethane Diisocyanate by Nose-Only Inhalation in Male Wistar Rats | Author: Randazzo J. | Year: 2017 | Adequacy: weight of evidence. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: An In Vivo Alkaline Comet Assay of 4,4'-Diphenylmethane Diisocyanate by Nose-Only Inhalation in Male Wistar Rats | Author: Randazzo J. | Year: 2017 | Adequacy: weight of evidence. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Bone marrow micronucleus assay in Brown-Norway rats exposed to diphenyl-methane-4,4'-diisocyanate | Author: Pauluhn J. et al. | Year: 2001 | Adequacy: weight of evidence. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: MDI: bone marrow micronucleus assay following inhalation exposure to the rat | Author: Pauluhn J. & Gollapudi B. | Year: 2001 | Adequacy: weight of evidence. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: MDI: bone marrow micronucleus assay following inhalation exposure to the rat | Author: Pauluhn J. & Gollapudi B. | Year: 2001 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E. | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Desmodur VP PU 1806: acute oral toxicity study in male and female Wistar rats | Author: Bomhard E. | Year: 1990 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Diphenylmethane 4,4'-diisocyanate (4,4'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Diphenylmethane 4,4'-diisocyanate (4,4'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: OECD Guideline 403 acute inhalation toxicity study for the no-longer-polymer (NLP) reaction product of 4,4'-MDI and diproplylene glycol (4,4'-MDI/DPG; EC 701-041-3). | Author: Hotchkiss J. A. and Weidemoyer L. J. | Year: 2020 | Guideline: 403 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: OECD Guideline 403 acute inhalation toxicity study for the no-longer-polymer (NLP) reaction product of 4,4'-MDI and diproplylene glycol (4,4'-MDI/DPG; EC 701-041-3). | Author: Hotchkiss J. A. and Weidemoyer L. J. | Year: 2020 | Guideline: 403 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute inhalation toxicity of an MDI pre-polymer in rats according to OECD Test Guideline 403. | Author: Kopf J. | Year: 2016 | Guideline: 403 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Acute inhalation toxicity of an MDI pre-polymer in rats according to OECD Test Guideline 403. | Author: Kopf J. | Year: 2016 | Guideline: 403 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Interrelating the acute and chronic mode of action of inhaled methylenediphenyl diisocyanate (MDI) in rats assisted by computational toxicology. | Author: Pauluhn J. | Year: 2011 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: MDI PIR: Acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2012 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: MDI PIR: Acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2012 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Desmodur 44 V 20 L: acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Desmodur 44 V 20 L: acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Diphenylmethane 22'-diisocyanate (22'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Diphenylmethane 22'-diisocyanate (22'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Diphenylmethane 24'-diisocyanate (24'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Diphenylmethane 24'-diisocyanate (24'-MDI): acute inhalation toxicity in rats (exposure 1x4 hours followed by a postexposure period of 2 weeks). | Author: Pauluhn J. | Year: 2008 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit. | Author: Wazeter F. X. Buller R. H. and Geil R. G. | Year: 1964 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute dermal toxicity studies (LD50) in the albino rabbit. | Author: Wazeter F. X. Buller R. H. and Geil R. G. | Year: 1964 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toxicological investigation of Mondur PF. | Author: Birch M. D. | Year: 1977 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Toxicological investigation of Mondur PF. | Author: Birch M. D. | Year: 1977 | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Project 705: In Silico Investigation of absorption and bioavailability of MDI prepolymers and major GSH conjugates after dermal or inhalation exposures using GastroPlus® in Support of the EU-REACH MDI Substance Grouping | Author: Bartels M. | Year: 2021 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Project 705: In Silico Investigation of absorption and bioavailability of MDI prepolymers and major GSH conjugates after dermal or inhalation exposures using GastroPlus® in Support of the EU-REACH MDI Substance Grouping | Author: Bartels M. | Year: 2021 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Chronic toxicity/carcinogenicity inhalation study of polymeric methylenediphenyl diisocyanate aerosol in rats. 3 vols | Author: Reuzel P.G.J. et al. | Year: 1990 | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Chronic toxicity/carcinogenicity inhalation study of polymeric methylenediphenyl diisocyanate aerosol in rats. 3 vols | Author: Reuzel P.G.J. et al. | Year: 1990 | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Chronic inhalation toxicity and carcinogenicity study of respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol in rats | Author: Reuzel P.G.J. et al. | Year: 1994 | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats: combination of findings from two bioassays | Author: Feron V.J. et al. | Year: 2001 | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Band 1 - 3 | Author: Hoymann H.G. et al. | Year: 1995 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal toxicity if inhaled polymeric methylenediphenyl diisocyanate (MDI) aerosols in pregnant Wistar rats. | Author: Gamer A. et al. | Year: 2000 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal toxicity of polymeric MDI in rats. Aerosol inhalation. 3 vols | Author: Gamer A.O. | Year: 1994 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal toxicity of polymeric MDI in rats. Aerosol inhalation. 3 vols | Author: Gamer A.O. | Year: 1994 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Untersuchungen zur chronischen Toxizität/Kanzerogenität von 4,4'-Methylendiphenyl-Diisocyanat (MDI). Band 1 - 3 | Author: Hoymann H.G. et al. | Year: 1995 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratogenicity study of monomeric 4,4'-methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats | Author: Buschmann J. | Year: 1994 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Embryotoxicity study of monomeric 4,4'-methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats | Author: Buschmann J. et al. | Year: 1996 | Adequacy: weight of evidence. | - |
| Toxicological | Developmental toxicity/teratogenicity | Waiver | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI | Author: Spoo-Klöppel M. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with Desmodur PF re-written 2010 | Author: CURRENTA | Year: 2010 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with Desmodur PF re-written 2010 | Author: CURRENTA | Year: 2010 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI/DPG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI/DPG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted) | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with 4,4'-MDI/DPG/HMWP (Monomer depleted) | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Fish Acute Toxicity Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Fish Acute Toxicity Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with MDI Polyisocyanurate | Author: Neuhahn A. | Year: 2021 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with MDI Polyisocyanurate | Author: Neuhahn A. | Year: 2021 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI Homopolymer | Author: Neuhahn A. | Year: 2021 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI Homopolymer | Author: Neuhahn A. | Year: 2021 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted) | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP (Monomer depleted) | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with MDI mixed isomers/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with MDI mixed isomers/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with Polymeric MDI | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with Polymeric MDI | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI/DPG/HMWP | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with MDI Polyisocyanurate | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with MDI Polyisocyanurate | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI Homopolymer | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia sp. Acute Immobilisation Test with 4,4'-MDI Homopolymer | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with 4,4'-MDI | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with (4,4'-) MDI/DPG | Author: Spoo-Klöppel M. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with MDI PIR | Author: Neuhahn A. | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with 4,4'-MDI/13-BD/TPG/PG | Author: Neuhahn A. | Year: 2016 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga Growth Inhibition Test with 4,4'-MDI/DPG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga Growth Inhibition Test with 4,4'-MDI/DPG | Author: Neuhahn A. | Year: 2020 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Effect of pMDI on the growth of the green alga Scenedesmus subspicatus | Author: Blom A.J.M. & Oldersma H. | Year: 1994 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Effect of pMDI on the growth of the green alga Scenedesmus subspicatus | Author: Blom A.J.M. & Oldersma H. | Year: 1994 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Report: 4,4'-MDI Determination of the Inhibition of Oxygen Consumption in the Activated Sludge Respiration Inhibition Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Report: 4,4'-MDI Determination of the Inhibition of Oxygen Consumption in the Activated Sludge Respiration Inhibition Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Report: 4,4'-MDI/DPG - Determination of the Inhibition of Oxygen Consumption in the Activated Sludge Respiration Inhibition Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Report: 4,4'-MDI/DPG - Determination of the Inhibition of Oxygen Consumption in the Activated Sludge Respiration Inhibition Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Activated Sludge Respiration Inhibition Test with MDI PIR | Author: CURRENTA | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Activated Sludge Respiration Inhibition Test with MDI PIR | Author: CURRENTA | Year: 2012 | Adequacy: weight of evidence. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Waiver | - |
| Environmental | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Determination of the LC50 (14 days) of TDI TDA MDI and MDA to the earthworm Eisenia fetida according to OECD guideline no. 207 | Author: van der Hoeven N., Roza P. and Henzen L | Year: 1992 | Guideline: 207 | Adequacy: key study. | - |
| Environmental | Toxicity to soil macro-organisms except arthropods | Right to refer to study -- Title: Determination of the LC50 (14 days) of TDI TDA MDI and MDA to the earthworm Eisenia fetida according to OECD guideline no. 207 | Author: van der Hoeven N., Roza P. and Henzen L | Year: 1992 | Guideline: 207 | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Waiver | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Estimated bioconcentration factor (BCF) values for MDI and TDI | Author: Tury B. | Year: 2010 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Right to refer to study -- Title: Estimated bioconcentration factor (BCF) values for MDI and TDI | Author: Tury B. | Year: 2010 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Biological effects and fate of Desmodur 44 V 20 (polymeric MDI) in artificial ponds by simulating an accidental pollution | Author: Heimbach F. | Year: 1993 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Right to refer to study -- Title: Biological effects and fate of Desmodur 44 V 20 (polymeric MDI) in artificial ponds by simulating an accidental pollution | Author: Heimbach F. | Year: 1993 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Bioconcentration of 4,4'-MDI in Cyprinus carpio: Test Number 50043 | Author: CERI | Year: 2002 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Right to refer to study -- Title: Bioconcentration of 4,4'-MDI in Cyprinus carpio: Test Number 50043 | Author: CERI | Year: 2002 | Adequacy: weight of evidence. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Waiver | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Water Extractability of Mixed Isomers MDI | Author: Neuland M. | Year: 2016 | Guideline: 120 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Water Extractability of Mixed Isomers MDI | Author: Neuland M. | Year: 2016 | Guideline: 120 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Water Extractability of Mixed Isomers MDI | Author: Neuland M. | Year: 2018 | Guideline: 120 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Water Extractability of Mixed Isomers MDI | Author: Neuland M. | Year: 2018 | Guideline: 120 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of hydrolysis behavior of 4,4'-MDI under homogenous reaction conditions | Author: Neluand M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of hydrolysis behavior of 4,4'-MDI under homogenous reaction conditions | Author: Neluand M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of hydrolysis behavior of Polymeric MDI under homogenous reaction conditions | Author: Neuland M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of hydrolysis behavior of Polymeric MDI under homogenous reaction conditions | Author: Neuland M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of hydrolysis behavior of 4,4'-MDI/DPG/HMWP under homogenous reaction conditions | Author: Neuland M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of hydrolysis behavior of 4,4'-MDI/DPG/HMWP under homogenous reaction conditions | Author: Neuland M. | Year: 2021 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of MDI PIR | Author: Richter Chr. | Year: 2012 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation of MDI PIR | Author: Richter Chr. | Year: 2012 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N. et al. | Year: 1986 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Report: 4,4'-MDI Determination of the Biodegradability in the Manometric Respiration Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Report: 4,4'-MDI Determination of the Biodegradability in the Manometric Respiration Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Report: 4,4'-MDI/DPG Determination of the Biodegradability in the Manometric Respiration Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Report: 4,4'-MDI/DPG Determination of the Biodegradability in the Manometric Respiration Test | Author: BASF SE | Year: 2019 | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: QSAR prediction of log Koc for 4,4'-MDI | Author: West B. | Year: 2021 | Adequacy: key study. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: QSAR prediction of log Koc for 4,4'-MDI | Author: West B. | Year: 2021 | Adequacy: key study. | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Rate of Degradation of 4,4'-MDI in Soil | Author: Holzaht-Grimme D. | Year: 2017 | Adequacy: key study. | - |
| Environmental | Biodegradation in soil | Right to refer to study -- Title: Rate of Degradation of 4,4'-MDI in Soil | Author: Holzaht-Grimme D. | Year: 2017 | Adequacy: key study. | - |