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CAS 4109-96-0 | Data Package 10 - 100 t/a

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Includes:

Study name Short Description Data Owner
Phys-Chem | Explosive properties Robust Study Summary -- Title: Explosive properties of the sample “Dichlorosilane” (DCS) (Safety tests according to the EEC-Directive 92/69/EWG, Annex V, method A.14) | Author: Nina Rediske | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Phys-Chem | Explosive properties Right to refer to study -- Title: Explosive properties of the sample “Dichlorosilane” (DCS) (Safety tests according to the EEC-Directive 92/69/EWG, Annex V, method A.14) | Author: Nina Rediske | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Phys-Chem | Flammability Robust Study Summary -- Title: Determination of lower explosion limit according to AQ-AG14-1794 | Author: Mekelburger H. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Phys-Chem | Flammability Right to refer to study -- Title: Determination of lower explosion limit according to AQ-AG14-1794 | Author: Mekelburger H. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Dichlorosilane Acute Vapour Inhalation Toxicity Test | Author: BRRC | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: Dichlorosilane Acute Vapour Inhalation Toxicity Test | Author: BRRC | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Silane A-199 Skin Irritancy Test | Author: BRRC | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Silane A-199 Skin Irritancy Test | Author: BRRC | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: 90-day inhalation toxicity study of hydrogen chloride gas in B6C3F1 mice, Sprague-Dawley rats and Fischer-344 rats. | Author: Toxigenics Inc. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: In Vitro Mammalian Chromosome Aberration test with Trimethoxysilane (CAS Number 2487-90-3) | Author: BioReliance | Year: 2007 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (CAS 2487-90-3 | Trimethoxysilane)
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Toxicological | in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: In Vitro Mammalian Chromosome Aberration test with Trimethoxysilane (CAS Number 2487-90-3) | Author: BioReliance | Year: 2007 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study.
Read-Across (CAS 2487-90-3 | Trimethoxysilane)
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Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Y-4398: Salmonella/Escherichia coli Preincubation Mutagenicity Assay with a Confirmatory Assay. | Author: Microbiological Associates | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Y-4398: Salmonella/Escherichia coli Preincubation Mutagenicity Assay with a Confirmatory Assay. | Author: Microbiological Associates | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Prenatal Toxicity of Synthetic Amorphous Silica Nanomaterial in rats. | Author: Hofmann T., Schneider S., Wolterbeek A., van de Sandt H., Landsiedel R. & van Ravenzwaay B. | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Safety of the metal scavengers sodium metasilicate and sodium polyphosphate. | Author: Saiwai K. et al. | Year: 1980; 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics: A Ready-Reference Book of Chemical and Physical Data | Author: Haynes W. M., Lide D. R. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics, 91st Edition, p4-86 | Author: Haynes W.M. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 75-78-5 | Dichlorodimethylsilane)
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Toxicological | Repeated dose toxicity: inhalation Right to refer to study -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Guideline: 412 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 75-78-5 | Dichlorodimethylsilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Environmental | Hydrolysis Right to refer to study -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Environmental | Hydrolysis Robust Study Summary -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Environmental | Hydrolysis Right to refer to study -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Environmental | Hydrolysis Robust Study Summary -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Environmental | Hydrolysis Right to refer to study -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning Corporation | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Phys-Chem | Flammability Robust Study Summary -- Title: Report on testing of the substance "trichlorosilane" and Expert's Opinion on transport and GHS classification | Author: Dr Heike Michael-Schulz | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 10025-78-2 | EC 233-042-5 | Trichlorosilane)
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Phys-Chem | Flammability Right to refer to study -- Title: Report on testing of the substance "trichlorosilane" and Expert's Opinion on transport and GHS classification | Author: Dr Heike Michael-Schulz | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 10025-78-2 | EC 233-042-5 | Trichlorosilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane)
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Environmental | Hydrolysis Right to refer to study -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane)
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Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Ethyl Silicate -Acute Toxicity to the Freshwater Green Alga, Pseudokirchneriella subcapitata. | Author: Springborn Smithers Laboratories | Year: 2008 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Ethyl Silicate -Acute Toxicity to the Freshwater Green Alga, Pseudokirchneriella subcapitata. | Author: Springborn Smithers Laboratories | Year: 2008 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1). | Author: Hüls A.G. | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1). | Author: Hüls A.G. | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Environmental | Hydrolysis Robust Study Summary -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane)
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Environmental | Hydrolysis Right to refer to study -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane)
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Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Trimethoxysilane Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Trimethoxysilane Acute Toxicity to Rainbow Trout (Oncorhynchus mykiss) Under Static Conditions. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Trimethoxysilane -Toxicity to the Freshwater Green Algae Pseudokirchneriella subcapitata. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Trimethoxysilane -Toxicity to the Freshwater Green Algae Pseudokirchneriella subcapitata. | Author: Springborn Smithers | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity Evaluation of Dow Corning Z-1210 Silane in the Ames bacterial assay | Author: Dow Corning Corporation | Year: 1981 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 10025-78-2 | EC 233-042-5 | Trichlorosilane)
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Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Mutagenicity Evaluation of Dow Corning Z-1210 Silane in the Ames bacterial assay | Author: Dow Corning Corporation | Year: 1981 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 10025-78-2 | EC 233-042-5 | Trichlorosilane)
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Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Evaluation of Trimethoxysilane via acute vapour inhalation in the rodent micronucleus assay | Author: Dow Corning Corporation | Year: 1982 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 2487-90-3 | EC 219-637-2 | Trimethoxysilane)
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Toxicological | Genetic toxicity in vivo Right to refer to study -- Title: Evaluation of Trimethoxysilane via acute vapour inhalation in the rodent micronucleus assay | Author: Dow Corning Corporation | Year: 1982 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 2487-90-3 | EC 219-637-2 | Trimethoxysilane)
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Environmental | Hydrolysis Robust Study Summary -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane)
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Environmental | Hydrolysis Right to refer to study -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Determination of the acute effects of DYNASIL A On the swimming behaviour of Daphnia magna (in accordance with EC 84/449, Nov. 1989) | Author: Hüls A.G. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Determination of the acute effects of DYNASIL A On the swimming behaviour of Daphnia magna (in accordance with EC 84/449, Nov. 1989) | Author: Hüls A.G. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (CAS 78-10-4 | EC 201-083-8 | Tetraethyl orthosilicate)
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Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Trimethoxysilane -Acute Toxicity to Daphnids (Daphnia magna) Under Static|Conditions. | Author: Springborn Smithers | Year: 2004 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Trimethoxysilane -Acute Toxicity to Daphnids (Daphnia magna) Under Static|Conditions. | Author: Springborn Smithers | Year: 2004 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics: A Ready-Reference Book of Chemical and Physical Data | Author: Haynes W. M., Lide D. R. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Density Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics: A Ready-Reference Book of Chemical and Physical Data | Author: Haynes W. M., Lide D. R. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -