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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: GESTIS Substance Database Polymeric diphenylmethane diisocyanate CAS: 9016-87-9 | Author: Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA) | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Polymeric diphenylmethane 4,4'-diisocyanate (PMDI): determination of physicochemical properties | Author: Fisk PR & Langner EJ | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Polymeric diphenylmethane 4,4'-diisocyanate (PMDI): determination of physicochemical properties | Author: Fisk PR & Langner EJ | Year: 1995 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Monographs on the Evaluation of the Carcinogenic Risk of Chemicals | Author: IARC | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor pressure of PMDI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Vapor pressure of PMDI | Author: BASF Polyurethanes GmbH | Year: 2016 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: Yakabe | Year: 1997 | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: No information | Author: Yakabe | Year: 1997 | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B et al. | Year: 1998 | Guideline: EU Method B.12/B.13 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Studies on the effect of the solvents dimethylsulphoxide and ethyleneglycoldimethylether on the mutagenicity of four types of diisocyanates in the salmonella/microsome test | Author: Herbold B et al. | Year: 1998 | Guideline: EU Method B.12/B.13 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toluene diisocyanate (TDI) and polymethylene polyphenylisocyanate (PAPI): acute toxicity studies (LD50) in male albino rats | Author: Wazeter FX et al. | Year: 1964 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N et al. | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Ecotoxicity of toluenediisocyanate (TDI), diphenylmethanediisocyanate (MDI), toluenediamine (TDA), diphenylmethanediamine (MDA) | Author: Caspers N et al. | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |