You are here: Home> Turkey>TR-REACH>CAS 37208-53-0> CAS 37208-53-0 | Data Package 100 - 1000 t/a (Affiliates of NLP Polyols Consortium members & ISOPA)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated (NLP-No: 500-094-8) | Author: BASF AG | Klimisch score: 4 - Not assignable | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated (NLP-No: 500-094-8) | Author: BASF AG | Klimisch score: 4 - Not assignable | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physicochemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Physicochemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physicochemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Physicochemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Currenta | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Currenta | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of the vapour pressure of 2,2',2''-nitrilotriethanol propoxylated NLP#15 according to OECD 104 resp. EU A.4 | Author: LAUS GmbH | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of the vapour pressure of 2,2',2''-nitrilotriethanol propoxylated NLP#15 according to OECD 104 resp. EU A.4 | Author: LAUS GmbH | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation of key physical-chemical properties for fifteen No-Longer-Polymer (NLP) polyether polyol substances | Author: West RJ | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Estimation of key physical-chemical properties for fifteen No-Longer-Polymer (NLP) polyether polyol substances | Author: West RJ | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Characterization and assessment of physico-chemical properties of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: EPIsuite 4.10 calculation with Ethylenediamine-N,N,N',N'-tetra-2-propanol | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Title: EPIsuite 4.10 calculation with Ethylenediamine-N,N,N',N'-tetra-2-propanol | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Currenta | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Currenta | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Explosive properties | Waiver | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Keldenich H.P. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of Safety-Relevant Data of 2,2',2''-Nitrilotriethanol propoxylated | Author: Keldenich H.P. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of the safety-relevant data of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of the safety-relevant data of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Stability in organic solvents and identity of relevant degradation products | Waiver | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute dermal irritation in the rabbit | Author: ISOPA Brussels | Year: 2002 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute dermal irritation in the rabbit | Author: ISOPA Brussels | Year: 2002 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute eye irritation in the rabbit | Author: ISOPA Brussels | Year: 2002 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute eye irritation in the rabbit | Author: ISOPA Brussels | Year: 2002 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: NLP #15 (2,2',2''-Nitrilotriethanol propoxylated) - Contact Hypersensitivity in Albino Guinea Pigs Maximization-Test | Author: Arcelin G. | Year: 2009 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: NLP #15 (22'2''-Nitrilotriethanol propoxylated) - Contact Hypersensitivity in Albino Guinea Pigs Maximization-Test | Author: Arcelin G. | Year: 2009 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: the local lymph node assay in the mouse | Author: ISOPA Brussels | Year: 2002 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: the local lymph node assay in the mouse | Author: ISOPA Brussels | Year: 2002 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: reverse mutation assay "Ames test" using Salmonella typhimurium | Author: ISOPA Brussels | Year: 2002 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: reverse mutation assay "Ames test" using Salmonella typhimurium | Author: ISOPA Brussels | Year: 2002 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: NLP#15 2,2',2''-Nitrilotriethanol propoxylated CAS#37208-53-0: Chromosome Aberration Test in Human Lymphocytes in vitro | Author: Wright N.P. | Year: 2006 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: NLP#15 2,2',2''-Nitrilotriethanol propoxylated CAS#37208-53-0: Chromosome Aberration Test in Human Lymphocytes in vitro | Author: Wright N.P. | Year: 2006 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated (NLP#15): V79/HPRT-Test in vitro for the detection of induced forward mutations | Author: Entian G. | Year: 2009 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated (NLP#15): V79/HPRT-Test in vitro for the detection of induced forward mutations | Author: Entian G. | Year: 2009 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute oral toxicity in the rat - acute toxic class method | Author: ISOPA Brussels | Year: 2002 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute oral toxicity in the rat - acute toxic class method | Author: ISOPA Brussels | Year: 2002 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Waiver | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute dermal irritation in the rat | Author: ISOPA Brussels | Year: 2002 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: 2,2',2''-Nitrilotriethanol propoxylated: acute dermal irritation in the rat | Author: ISOPA Brussels | Year: 2002 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Grouping of NLP 'Polyols' and their Toxicokinetics Assessments | Author: Paul Illing Consultancy Services Ltd. and Marlin Consultancy | Year: 2007 | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Grouping of NLP 'Polyols' and their Toxicokinetics Assessments | Author: Paul Illing Consultancy Services Ltd. and Marlin Consultancy | Year: 2007 | Adequacy: weight of evidence. | - |
| Toxicological | Repeated dose toxicity: oral | Waiver | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: 22'2"-Nitrilotriethanol propoxylated; Subacute Oral Toxicity Study in Wistar Rats (4 Weeks Administration by Gavage) | Author: Schladt L. | Year: 2005 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: 22'2"-Nitrilotriethanol propoxylated; Subacute Oral Toxicity Study in Wistar Rats (4 Weeks Administration by Gavage) | Author: Schladt L. | Year: 2005 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Waiver | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: 2,2',2''Nitrilotriethanol propoxylated Reproduction/Developmental Toxicity Screening Test in Rats after Oral Administration | Author: Bayer HealthCare AG | Year: 2005 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: 2,2',2''Nitrilotriethanol propoxylated Reproduction/Developmental Toxicity Screening Test in Rats after Oral Administration | Author: Bayer HealthCare AG | Year: 2005 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Waiver | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: Incident report of workers exposed to D40 | Author: Smith D.H. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Right to refer to study -- Title: Incident report of workers exposed to D40 | Author: Smith D.H. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Fish Toxicity of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute Fish Toxicity of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Daphnia Toxicity of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute Daphnia Toxicity of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Alga growth inhibition test of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Alga growth inhibition test of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Toxicity to bacteria of 2,2',2''-Nitrilotrietanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Toxicity to bacteria of 2,2',2''-Nitrilotrietanol propoxylated | Author: ISOPA Brussels | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia magna reproduction test | Author: ISOPA | Year: 2005 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 26316-40-5 | EC 500-047-1 | Ethylenediamine, ethoxylated and propoxylated) |
- |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Daphnia magna reproduction test | Author: ISOPA | Year: 2005 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 26316-40-5 | EC 500-047-1 | Ethylenediamine, ethoxylated and propoxylated) |
- |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Waiver | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of the hydrolysis of Polyether V 531 | Author: Bayer Material Science AG | Year: 2009 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 50586-59-9 | EC 500-110-3 | Propylidynetrimethanol, ethoxylated) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of the hydrolysis of Polyether V 531 | Author: Bayer Material Science AG | Year: 2009 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 50586-59-9 | EC 500-110-3 | Propylidynetrimethanol, ethoxylated) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation of 2,2',2''-Nitrilotriethanol propoxylated | Author: ISOPA | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Environmental | Biodegradation in soil | Waiver | - |
| Environmental | Bioaccumulation: aquatic/sediment | Waiver | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: EPIsuite 4.10 calculation with Ethylenediamine-N,N,N',N'-tetra-2-propanol | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: EPIsuite 4.10 calculation with Ethylenediamine-N,N,N',N'-tetra-2-propanol | Author: BASF SE | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Determination of adsorption coefficient | Author: ISOPA | Year: 2008 | Guideline: 121 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Determination of adsorption coefficient | Author: ISOPA | Year: 2008 | Guideline: 121 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |