You are here: Home> South Korea>K-REACH>CAS 75277-39-3> CAS 75277-39-3 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: "HEPES sodium salt": Melting Temperature | Author: Pamela Schlegl | Year: 2015 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: "HEPES sodium salt": Melting Temperature | Author: Pamela Schlegl | Year: 2015 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: "HEPES sodium salt": Melting Temperature | Author: Pamela Schlegl | Year: 2015 | Guideline: 102 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: "HEPES sodium salt": Melting Temperature | Author: Pamela Schlegl | Year: 2015 | Guideline: 102 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: "HEPES sodium salt": Relative Density | Author: Pamela Schlegl | Year: 2015 | Guideline: 109 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: "HEPES sodium salt": Relative Density | Author: Pamela Schlegl | Year: 2015 | Guideline: 109 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: Determination of the Particle Size Distribution of HEPES Sodium Salt | Author: Christian Bär | Year: 2016 | Guideline: 110 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: Determination of the Particle Size Distribution of HEPES Sodium Salt | Author: Christian Bär | Year: 2016 | Guideline: 110 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: "HEPES sodium salt: Vapour Pressure | Author: Pamela Schlegl | Year: 2015 | Guideline: 104 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: "HEPES sodium salt: Vapour Pressure | Author: Pamela Schlegl | Year: 2015 | Guideline: 104 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: "HEPES sodium salt": Partition Coefficient | Author: Pamela Schlegl | Year: 2015 | Guideline: 107 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: "HEPES sodium salt": Partition Coefficient | Author: Pamela Schlegl | Year: 2015 | Guideline: 107 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: "HEPES sodium salt": Water Solubility | Author: Pamela Schlegl | Year: 2015 | Guideline: 105 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: "HEPES sodium salt": Water Solubility | Author: Pamela Schlegl | Year: 2015 | Guideline: 105 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: "HEPES sodium salt": Surface Tension | Author: Pamela Schlegl | Year: 2015 | Guideline: 115 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: "HEPES sodium salt": Surface Tension | Author: Pamela Schlegl | Year: 2015 | Guideline: 115 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: "HEPES sodium slat": Relative Self-Ignition Temperature | Author: Pamela Schlegl | Year: 2015 | Guideline: A.16 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: "HEPES sodium slat": Relative Self-Ignition Temperature | Author: Pamela Schlegl | Year: 2015 | Guideline: A.16 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: "HEPES sodium salt": Flammability | Author: Pamela Schlegl | Year: 2015 | Guideline: A.10 | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: "HEPES sodium salt": Flammability | Author: Pamela Schlegl | Year: 2015 | Guideline: A.10 | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Art. 110110 - Determination of pH-dependent Hydrolysis in Water of the test substance according to OECD Guideline 111 | Author: Brinkmann | Year: 2012 | Guideline: 111 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Environmental | Hydrolysis | Right to refer to study -- Title: Art. 110110 - Determination of pH-dependent Hydrolysis in Water of the test substance according to OECD Guideline 111 | Author: Brinkmann | Year: 2012 | Guideline: 111 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ready Biodegradability of the test substance in a Closed Bottle Test | Author: Dr. Johannes Hertl | Year: 2001 | Guideline: 301D | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ready Biodegradability of the test substance in a Closed Bottle Test | Author: Dr. Johannes Hertl | Year: 2001 | Guideline: 301D | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Art. 110110 - Acute Toxicity of the test substance on Zebrafish (Brachydanio rerio) | Author: Agh | Year: 2013 | Guideline: 203 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Art. 110110 - Acute Toxicity of the test substance on Zebrafish (Brachydanio rerio) | Author: Agh | Year: 2013 | Guideline: 203 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Immobilization Test to Daphnia magna, Static, 48 hours | Author: Dr. Volker Klix | Year: 2018 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute Immobilization Test to Daphnia magna, Static, 48 hours | Author: Dr. Volker Klix | Year: 2018 | Guideline: 202 | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Growth Inhibition Test on Algae (Pseudokirchneriella subcapitata) | Author: Agh | Year: 2013 | Guideline: 201 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Growth Inhibition Test on Algae (Pseudokirchneriella subcapitata) | Author: Agh | Year: 2013 | Guideline: 201 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicokinetic Assessment | Author: SCC Scientific Consulting GmbH | Year: 2022 | Adequacy: key study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Toxicokinetic Assessment | Author: SCC Scientific Consulting GmbH | Year: 2022 | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute toxicity study in rats after oral administration (ATC-method) | Author: Heusener, A. | Year: 2000 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute toxicity study in rats after oral administration (ATC-method) | Author: Heusener, A. | Year: 2000 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: In Vitro Skin Irritation Test with HEPES sodium salt in the EPISKIN Model | Author: István Buda | Year: 2016 | Guideline: 439 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: In Vitro Skin Irritation Test with HEPES sodium salt in the EPISKIN Model | Author: István Buda | Year: 2016 | Guideline: 439 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: HEPES sodium salt: In vitro test for eye corrosives and sever irritants in isolated chocken eyes | Author: István Buda | Year: 2016 | Guideline: 438 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: HEPES sodium salt: In vitro test for eye corrosives and sever irritants in isolated chocken eyes | Author: István Buda | Year: 2016 | Guideline: 438 | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: (2-[4-(2-Hydroxyethyl)-l-piperazinyl]-ethanesulfonic acid = HEPES) - Guinea pig maximization test according to Magnusson and Kligman | Author: Heusener, A. | Year: 2002 | Guideline: 406 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: (2-[4-(2-Hydroxyethyl)-l-piperazinyl]-ethanesulfonic acid = HEPES) - Guinea pig maximization test according to Magnusson and Kligman | Author: Heusener, A. | Year: 2002 | Guideline: 406 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: HEPES sodium salt: Salmonella typhimurium and Escherichia coli reverse mutation assay | Author: Dr. Steffi Chang | Year: 2017 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: HEPES sodium salt: Salmonella typhimurium and Escherichia coli reverse mutation assay | Author: Dr. Steffi Chang | Year: 2017 | Guideline: 471 | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: In Vitro Mammalian Cell Gene Mutation Test (L5178Y/TK+/- Mouse Lymphoma Assay) | Author: Clarke, J. | Year: 2013 | Guideline: 476 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: In Vitro Mammalian Cell Gene Mutation Test (L5178Y/TK+/- Mouse Lymphoma Assay) | Author: Clarke, J. | Year: 2013 | Guideline: 476 | Adequacy: key study | GLP: Y. Read-Across (CAS 7365-45-9 | EC 230-907-9 | HEPES) |
- |
| Read Across Justification | Read Across Justification -- Title: Read-across hypothesis and justification for sodium 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonate.. | - |