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| Study name | Short Description | Data Owner |
|---|---|---|
| Melting point/freezing point | Robust Study Summary - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 102; Klimisch score: 2 | public |
| Melting point/freezing point | Right to refer to study - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 102; Klimisch score: 2 | public |
| Boiling point | Robust Study Summary - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 103; Klimisch score: 2 | public |
| Boiling point | Right to refer to study - Title: International Chemical Safety Cards (ICSC) ; Author: NIOSH; Year: 1993; Guideline: 103; Klimisch score: 2 | public |
| Density | Robust Study Summary - Title: Isocyanate; Author: Eisenmann, K.-H. & Zenner, K.-F.; Year: 1977; Guideline: 109; Klimisch score: 2 | public |
| Density | Right to refer to study - Title: Isocyanate; Author: Eisenmann, K.-H. & Zenner, K.-F.; Year: 1977; Guideline: 109; Klimisch score: 2 | Publication |
| Vapour pressure | Robust Study Summary - Title: Analytische Methoden zur Pr³fung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat; Author: Henschler, D.; Year: 1988; Guideline: 104; Klimisch score: 2 | public |
| Vapour pressure | Right to refer to study - Title: Analytische Methoden zur Pr³fung gesundheitsschaedlicher|Arbeitsstoffe: Hexamethylendiiosocyanat; Author: Henschler, D.; Year: 1988; Guideline: 104; Klimisch score: 2 | Publication |
| Water solubility | Robust Study Summary - Title: waived | public |
| Water solubility | Right to refer to study - Title: waived | public |
| Partition coefficient | Robust Study Summary - Title: waived | public |
| Partition coefficient | Right to refer to study - Title: waived | public |
| Partition coefficient | Robust Study Summary - Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin; Author: Dr. Brunner; Year: 1988; Guideline: 107/117; Klimisch score: 2 | Consortium |
| Partition coefficient | Right to refer to study - Title: Octanol-Wasser-Verteilungskoeffizient Pow von Hexamethylendiamin; Author: Dr. Brunner; Year: 1988; Guideline: 107/117; Klimisch score: 2 | BASF AG |
| Particle size distribution (Granulometry) | Robust Study Summary - Title: waived | public |
| Particle size distribution (Granulometry) | Right to refer to study - Title: waived | public |
| Acute toxicity: oral | Robust Study Summary - Title: Desmodur H: Toxikologische Untersuchungen; Author: Kimmerle G et al.; Year: 1970; Guideline: 420, 423, 425; Klimisch score: 2 | Consortium |
| Acute toxicity: oral | Right to refer to study - Title: Desmodur H: Toxikologische Untersuchungen; Author: Kimmerle G et al.; Year: 1970; Guideline: 420, 423, 425; Klimisch score: 2 | Covestro Deutschland AG |
| Acute toxicity: oral | Robust Study Summary - Title: Range-finding toxicity data: List VII; Author: Smyth Jr HF et al.; Year: 1969; Guideline: 420, 423, 425; Klimisch score: 2 | public |
| Acute toxicity: oral | Right to refer to study - Title: Range-finding toxicity data: List VII; Author: Smyth Jr HF et al.; Year: 1969; Guideline: 420, 423, 425; Klimisch score: 2 | Publication |
| Skin irritation / corrosion | Robust Study Summary - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf primõre Hautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 404; Klimisch score: 2 | Consortium |
| Skin irritation / corrosion | Right to refer to study - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf primõre Hautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 404; Klimisch score: 2 | Covestro Deutschland AG |
| Skin sensitisation | Robust Study Summary - Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut ; Author: Schmidt WM and Bomhard E; Year: 1983; Guideline: 406, 429; Klimisch score: 2 | Consortium |
| Skin sensitisation | Right to refer to study - Title: Hexamethylen-1,6-diisocyanat (HDI): Untersuchungen zur sensibilisierenden Wirkung an der Meerschweinchenhaut ; Author: Schmidt WM and Bomhard E; Year: 1983; Guideline: 406, 429; Klimisch score: 2 | Covestro Deutschland AG |
| Genetic toxicity in vitro | Robust Study Summary - Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate /Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Wagner VO and Klug ML / Wagner VO et al.; Year: 1998 / 2000; Guideline: 471; Klimisch score: 2 | Consortium |
| Genetic toxicity in vitro | Right to refer to study - Title: Bacterial reverse mutation assay using vapor-phase exposure for 1,6-hexamethylene diisocyanate /Lack of mutagenic activity of 1,6-hexamethylene diisocyanate; Author: Wagner VO and Klug ML / Wagner VO et al.; Year: 1998 / 2000; Guideline: 471; Klimisch score: 2 | "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)" |
| Genetic toxicity in vitro | Robust Study Summary - Title: In vitro mammalian cell gene mutation test with an independent repeat assay using vapor-phase exposure to 1,6-hexamethylene diisocyanate; Author: San RHC and Clarke JJ; Year: 1998; Guideline: 471; Klimisch score: 2 | Consortium |
| Genetic toxicity in vitro | Right to refer to study - Title: In vitro mammalian cell gene mutation test with an independent repeat assay using vapor-phase exposure to 1,6-hexamethylene diisocyanate; Author: San RHC and Clarke JJ; Year: 1998; Guideline: 471; Klimisch score: 2 | "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)" |
| Short-term toxicity to fish | Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 203; Klimisch score: 2 | Consortium |
| Short-term toxicity to fish | Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 203; Klimisch score: 2 | Covestro Deutschland AG |
| Short-term toxicity to aquatic invertebrates | Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 202; Klimisch score: 2 | Consortium |
| Short-term toxicity to aquatic invertebrates | Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 202; Klimisch score: 2 | Covestro Deutschland AG |
| Biodegradation in water: screening tests | Robust Study Summary - Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test.; Author: Bayer AG; Year: 2000; Guideline: 301C; Klimisch score: 1 | Consortium |
| Biodegradation in water: screening tests | Right to refer to study - Title: Biodegradation of "Desmodur H rein" according to the manometric respiratory test.; Author: Bayer AG; Year: 2000; Guideline: 301C; Klimisch score: 1 | Covestro Deutschland AG |
| Flammability | Robust Study Summary - Title: waived | public |
| Flammability | Right to refer to study - Title: waived | public |
| Explosiveness | Robust Study Summary - Title: waived | public |
| Explosiveness | Right to refer to study - Title: waived | public |
| Oxidising properties | Robust Study Summary - Title: waived | public |
| Oxidising properties | Right to refer to study - Title: waived | public |
| Hydrolysis | Robust Study Summary - Title: NCO-Abnahme in Wasser; Author: Bayer AG; Year: 1999; Guideline: 111; Klimisch score: 2 | Consortium |
| Hydrolysis | Right to refer to study - Title: NCO-Abnahme in Wasser; Author: Bayer AG; Year: 1999; Guideline: 111; Klimisch score: 2 | Covestro Deutschland AG |
| Hydrolysis | Robust Study Summary - Title: Zur Frage der Bedeutung der Stabilitõt von Diisocyanaten in Wasser bei hygienischer Normierung.; Author: Sopac, E.D. & Boltromejuk, L.P.; Year: 1974; Guideline: 111; Klimisch score: 2 | public |
| Hydrolysis | Right to refer to study - Title: Zur Frage der Bedeutung der Stabilitõt von Diisocyanaten in Wasser bei hygienischer Normierung.; Author: Sopac, E.D. & Boltromejuk, L.P.; Year: 1974; Guideline: 111; Klimisch score: 2 | Publication |
| Acute toxicity: dermal | Robust Study Summary - Title: Akute dermale Toxizitõt von Hexamethylendiisocyanat-1,6 (HDI) f³r Ratten; Author: M³rmann P; Year: 1985; Guideline: 402; Klimisch score: 2 | Consortium |
| Acute toxicity: dermal | Right to refer to study - Title: Akute dermale Toxizitõt von Hexamethylendiisocyanat-1,6 (HDI) f³r Ratten; Author: M³rmann P; Year: 1985; Guideline: 402; Klimisch score: 2 | Evonik Resource Efficiency GmbH |
| Acute toxicity: inhalation | Robust Study Summary - Title: 1,6-Hexamethylene diisocyanate (Desmodur H): Study on acute inhalation toxicity in rats according to OECD No. 403; Author: Pauluhn J; Year: 1997; Guideline: 403; Klimisch score: 1 | Consortium |
| Acute toxicity: inhalation | Right to refer to study - Title: 1,6-Hexamethylene diisocyanate (Desmodur H): Study on acute inhalation toxicity in rats according to OECD No. 403; Author: Pauluhn J; Year: 1997; Guideline: 403; Klimisch score: 1 | Covestro Deutschland AG |
| Eye irritation | Robust Study Summary - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf Schleimhautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 405; Klimisch score: 2 | Consortium |
| Eye irritation | Right to refer to study - Title: Bericht ³ber die Pr³fung von Hexamethylen-1,6-diisocyanat auf Schleimhautreizwirkung; Author: Schreiber G; Year: 1981; Guideline: 405; Klimisch score: 2 | Covestro Deutschland AG |
| Genetic toxicity in vitro | Robust Study Summary - Title: waived | public |
| Genetic toxicity in vitro | Right to refer to study - Title: waived | public |
| Repeated dose toxicity: oral | Robust Study Summary - Title: waived | public |
| Repeated dose toxicity: oral | Right to refer to study - Title: waived | public |
| Repeated dose toxicity: inhalation | Robust Study Summary - Title: 90-day inhalation toxicity study with 1,6-hexamethylene diisocyanate (HDI) in rats; Author: Shiotsuka RN; Year: 1988; Guideline: 413; Klimisch score: 1 | Consortium |
| Repeated dose toxicity: inhalation | Right to refer to study - Title: 90-day inhalation toxicity study with 1,6-hexamethylene diisocyanate (HDI) in rats; Author: Shiotsuka RN; Year: 1988; Guideline: 413; Klimisch score: 1 | "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)" |
| Toxicity to reproduction | Robust Study Summary - Title: A combined repeated dose toxicity study with the reproduction/developmental toxicity screening test using 1,6-hexamethylene diisocyanate (HDI) in the Sprague-Dawley rat; Author: Astroff AB; Year: 1999; Guideline: 421, 422; Klimisch score: 1 | Consortium |
| Toxicity to reproduction | Right to refer to study - Title: A combined repeated dose toxicity study with the reproduction/developmental toxicity screening test using 1,6-hexamethylene diisocyanate (HDI) in the Sprague-Dawley rat; Author: Astroff AB; Year: 1999; Guideline: 421, 422; Klimisch score: 1 | "Co-ownership: Covestro LLC, Vencorex France (Study sponsor: Chemical Manufactures Association, Arlington, VA, USA)" |
| Toxicity to aquatic algae and cyanobacteria | Robust Study Summary - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 201; Klimisch score: 2 | Consortium |
| Toxicity to aquatic algae and cyanobacteria | Right to refer to study - Title: Internal report: Investigation of the ecological properties of Desmodur H rein; Author: Bayer AG; Year: 2000; Guideline: 201; Klimisch score: 2 | Covestro Deutschland AG |
| CSR | CSR | Consortium |